Aberrant Salience, Information Processing, and Dopaminergic Signaling in People at Clinical High Risk for Psychosis

The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain’s abil...

Full description

Saved in:
Bibliographic Details
Published inBiological psychiatry (1969) Vol. 88; no. 4; pp. 304 - 314
Main Authors Howes, Oliver D., Hird, Emily J., Adams, Rick A., Corlett, Philip R., McGuire, Philip
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 15.08.2020
Subjects
Bayes Theorem
Cognition
Computational psychiatry
Dopamine
Humans
Imaging
Prodrome
Psychiatric/Mental Health
Psychosis
Psychotic Disorders
Reward
Risk
Schizophrenia
Psychosis
Schizophrenia
Prodrome
Risk
Computational psychiatry
Imaging
Online AccessGet full text
ISSN0006-3223
1873-2402
1873-2402
DOI10.1016/j.biopsych.2020.03.012

Cover

Abstract The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain’s ability to predict and make inferences about the world (predictive processing) provide a new perspective on this hypothesis. We review these and summarize the evidence for dopamine dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychosis (CHR) relative to findings in patients with psychosis. This review identifies consistent evidence for dysregulated subcortical dopamine function in people at CHR, but also indicates a number of areas where neurobiological processes are different in CHR subjects relative to patients with psychosis, particularly in reward processing. We then consider how predictive processing models may explain psychotic symptoms in terms of alterations in prediction error and precision signaling using Bayesian approaches. We also review the potential role of environmental risk factors, particularly early adverse life experiences, in influencing the prior expectations that individuals have about their world in terms of computational models of the progression from being at CHR to frank psychosis. We identify a number of key outstanding questions, including the relative roles of prediction error or precision signaling in the development of symptoms and the mechanism underlying dopamine dysfunction. Finally, we discuss how the integration of computational psychiatry with biological investigation may inform the treatment for people at CHR of psychosis.
AbstractList The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain’s ability to predict and make inferences about the world (predictive processing) provide a new perspective on this hypothesis. We review these and summarize the evidence for dopamine dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychosis (CHR) relative to findings in patients with psychosis. This review identifies consistent evidence for dysregulated subcortical dopamine function in people at CHR, but also indicates a number of areas where neurobiological processes are different in CHR subjects relative to patients with psychosis, particularly in reward processing. We then consider how predictive processing models may explain psychotic symptoms in terms of alterations in prediction error and precision signaling using Bayesian approaches. We also review the potential role of environmental risk factors, particularly early adverse life experiences, in influencing the prior expectations that individuals have about their world in terms of computational models of the progression from being at CHR to frank psychosis. We identify a number of key outstanding questions, including the relative roles of prediction error or precision signaling in the development of symptoms and the mechanism underlying dopamine dysfunction. Finally, we discuss how the integration of computational psychiatry with biological investigation may inform the treatment for people at CHR of psychosis.
The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain's ability to predict and make inferences about the world (predictive processing) provide a new perspective on this hypothesis. We review these and summarize the evidence for dopamine dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychosis (CHR) relative to findings in patients with psychosis. This review identifies consistent evidence for dysregulated subcortical dopamine function in people at CHR, but also indicates a number of areas where neurobiological processes are different in CHR subjects relative to patients with psychosis, particularly in reward processing. We then consider how predictive processing models may explain psychotic symptoms in terms of alterations in prediction error and precision signaling using Bayesian approaches. We also review the potential role of environmental risk factors, particularly early adverse life experiences, in influencing the prior expectations that individuals have about their world in terms of computational models of the progression from being at CHR to frank psychosis. We identify a number of key outstanding questions, including the relative roles of prediction error or precision signaling in the development of symptoms and the mechanism underlying dopamine dysfunction. Finally, we discuss how the integration of computational psychiatry with biological investigation may inform the treatment for people at CHR of psychosis.The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain's ability to predict and make inferences about the world (predictive processing) provide a new perspective on this hypothesis. We review these and summarize the evidence for dopamine dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychosis (CHR) relative to findings in patients with psychosis. This review identifies consistent evidence for dysregulated subcortical dopamine function in people at CHR, but also indicates a number of areas where neurobiological processes are different in CHR subjects relative to patients with psychosis, particularly in reward processing. We then consider how predictive processing models may explain psychotic symptoms in terms of alterations in prediction error and precision signaling using Bayesian approaches. We also review the potential role of environmental risk factors, particularly early adverse life experiences, in influencing the prior expectations that individuals have about their world in terms of computational models of the progression from being at CHR to frank psychosis. We identify a number of key outstanding questions, including the relative roles of prediction error or precision signaling in the development of symptoms and the mechanism underlying dopamine dysfunction. Finally, we discuss how the integration of computational psychiatry with biological investigation may inform the treatment for people at CHR of psychosis.
AbstractThe aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain’s ability to predict and make inferences about the world (predictive processing) provide a new perspective on this hypothesis. We review these and summarize the evidence for dopamine dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychosis (CHR) relative to findings in patients with psychosis. This review identifies consistent evidence for dysregulated subcortical dopamine function in people at CHR, but also indicates a number of areas where neurobiological processes are different in CHR subjects relative to patients with psychosis, particularly in reward processing. We then consider how predictive processing models may explain psychotic symptoms in terms of alterations in prediction error and precision signaling using Bayesian approaches. We also review the potential role of environmental risk factors, particularly early adverse life experiences, in influencing the prior expectations that individuals have about their world in terms of computational models of the progression from being at CHR to frank psychosis. We identify a number of key outstanding questions, including the relative roles of prediction error or precision signaling in the development of symptoms and the mechanism underlying dopamine dysfunction. Finally, we discuss how the integration of computational psychiatry with biological investigation may inform the treatment for people at CHR of psychosis.
Author McGuire, Philip
Howes, Oliver D.
Adams, Rick A.
Hird, Emily J.
Corlett, Philip R.
Author_xml – sequence: 1
  givenname: Oliver D.
  orcidid: 0000-0002-2928-1972
  surname: Howes
  fullname: Howes, Oliver D.
  email: oliver.howes@kcl.ac.uk
  organization: Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
– sequence: 2
  givenname: Emily J.
  orcidid: 0000-0001-6599-7292
  surname: Hird
  fullname: Hird, Emily J.
  organization: Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
– sequence: 3
  givenname: Rick A.
  orcidid: 0000-0002-7661-8881
  surname: Adams
  fullname: Adams, Rick A.
  organization: Centre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom
– sequence: 4
  givenname: Philip R.
  surname: Corlett
  fullname: Corlett, Philip R.
  organization: Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut
– sequence: 5
  givenname: Philip
  surname: McGuire
  fullname: McGuire, Philip
  organization: Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32430200$$D View this record in MEDLINE/PubMed
BookMark eNqNkl9r2zAUxcXoWNNuX6HocQ-1dyU5lgNjrGR_WiisLH0XsnLtKrUlT3IK-faTm-SlD-uehMQ5R5fzu2fkxHmHhFwwyBmw8tMmr60f4s485Bw45CByYPwNmbFKiowXwE_IDADKTHAuTslZjJt0lZyzd-RU8EIkF8xIvKoxBO1GutKdRWfwkt64xodej9Y7ehe8wRitay-pdmv6zQ-6tw5Daw1d2dYll2upTUr0Q4dUj3SZnqzRHb227QP9beMjTYH0bprWRxvfk7eN7iJ-OJzn5P7H9_vldXb76-fN8uo2M_OiGDPBjOQLzRopGBbVAqtKQl2VyGSpNTaIBkpYNDUD3hgpa7nA5KwrDZpBLc7Jx33sEPyfLcZR9TYa7Drt0G-jSiXNBczLqkzSi4N0W_e4VkOwvQ47dewpCT7vBSb4GAM2ytjxuaExaNspBmrCojbqiEVNWBQIlbAke_nCfvzhVePXvRFTT08Wg4rmmdLaBjSjWnv7esSXFxHmwOcRdxg3fhsSxKiYilyBWk1LM-0MB8FEJYp_B_zPBH8BWHDV0A
CitedBy_id crossref_primary_10_1038_s41598_024_53468_4
crossref_primary_10_1016_j_pnpbp_2024_111206
crossref_primary_10_1038_s41537_025_00578_1
crossref_primary_10_3389_fpsyt_2024_1309868
crossref_primary_10_1016_j_neubiorev_2020_11_021
crossref_primary_10_1038_s41380_022_01554_2
crossref_primary_10_1093_schbul_sbad170
crossref_primary_10_1159_000520331
crossref_primary_10_1016_j_pscychresns_2020_111215
crossref_primary_10_1093_schbul_sbac163
crossref_primary_10_1038_s41380_023_02043_w
crossref_primary_10_1007_s00213_025_06753_7
crossref_primary_10_1007_s00406_022_01528_z
crossref_primary_10_3389_fpsyt_2023_1143315
crossref_primary_10_1016_j_jad_2024_10_054
crossref_primary_10_1038_s41598_024_68004_7
crossref_primary_10_1093_schbul_sbad169
crossref_primary_10_1093_schbul_sbad129
crossref_primary_10_1017_S003329172400326X
crossref_primary_10_3389_fnins_2021_640502
crossref_primary_10_3389_fpsyt_2024_1371763
crossref_primary_10_3390_brainsci12101338
crossref_primary_10_1093_schbul_sbad084
crossref_primary_10_1038_s41380_024_02495_8
crossref_primary_10_3389_fpsyt_2021_685390
crossref_primary_10_1038_s41537_023_00339_y
crossref_primary_10_1016_j_neubiorev_2022_104713
crossref_primary_10_1111_sjop_12806
crossref_primary_10_1038_s41582_023_00904_0
crossref_primary_10_1523_ENEURO_0270_21_2021
crossref_primary_10_1016_j_biopsych_2022_09_029
crossref_primary_10_1016_j_schres_2024_08_007
crossref_primary_10_1038_s41386_022_01451_w
crossref_primary_10_1016_j_clinph_2024_11_015
crossref_primary_10_1124_pharmrev_121_000514
crossref_primary_10_1016_j_neubiorev_2021_06_020
crossref_primary_10_1017_S0033291724003209
crossref_primary_10_1016_j_biopsych_2020_06_008
crossref_primary_10_1038_s41598_024_55359_0
crossref_primary_10_1016_j_schres_2024_07_025
crossref_primary_10_1016_j_schres_2022_02_002
crossref_primary_10_1186_s12888_024_06176_2
crossref_primary_10_3390_jcm10184126
crossref_primary_10_1093_schizbullopen_sgab054
crossref_primary_10_1111_sjp_12592
crossref_primary_10_1016_j_neubiorev_2024_105699
crossref_primary_10_1080_08039488_2021_1942547
crossref_primary_10_1093_schizbullopen_sgac074
crossref_primary_10_1016_j_biopsych_2022_06_017
crossref_primary_10_1080_15265161_2024_2416140
crossref_primary_10_1002_jmri_27924
crossref_primary_10_1016_j_jpsychires_2023_01_014
crossref_primary_10_1038_s41398_021_01720_0
crossref_primary_10_1016_j_bpsc_2021_01_006
crossref_primary_10_1038_s41386_023_01779_x
crossref_primary_10_3389_fpsyt_2023_1170168
crossref_primary_10_1038_s41380_022_01861_8
crossref_primary_10_1093_braincomms_fcab026
crossref_primary_10_1093_schizbullopen_sgac039
crossref_primary_10_1002_hbm_26649
Cites_doi 10.1093/schbul/sbz089
10.1016/S0140-6736(13)62036-X
10.1093/schbul/sby015.204
10.1016/j.schres.2014.06.041
10.1016/j.biopsych.2016.07.014
10.1523/JNEUROSCI.0200-14.2014
10.1016/j.tins.2018.12.004
10.3389/fpsyt.2013.00047
10.1073/pnas.0811507106
10.1016/j.schres.2013.07.004
10.1111/j.1600-0447.2011.01805.x
10.1016/j.biopsych.2012.11.017
10.1016/j.euroneuro.2012.04.015
10.1001/jamapsychiatry.2014.2414
10.1016/j.neuroimage.2005.07.051
10.1016/j.tins.2007.03.006
10.1126/science.1077349
10.1093/schbul/sbx042
10.1007/s00213-009-1561-0
10.1177/0269881107077716
10.1016/j.neuron.2010.11.022
10.1016/j.neuropsychologia.2012.09.045
10.1159/000337130
10.1093/schbul/sbs147
10.1038/npp.2010.126
10.1093/schbul/sbq031
10.1016/j.biopsych.2018.05.015
10.1038/mp.2009.108
10.1001/jamapsychiatry.2015.2196
10.1017/S0033291716002439
10.1073/pnas.1809298115
10.1093/schbul/sbp006
10.1016/j.cub.2017.02.026
10.1038/mp.2011.20
10.1093/brain/awm173
10.1001/jamapsychiatry.2017.2943
10.1016/j.pscychresns.2011.07.003
10.1016/j.pscychresns.2012.06.003
10.1093/schbul/sbx180
10.1176/appi.ajp.162.1.12
10.1162/jocn.2009.21233
10.1016/j.ijdevneu.2010.08.002
10.1016/j.biopsych.2013.02.016
10.1371/journal.pcbi.1004622
10.1073/pnas.97.14.8104
10.1073/pnas.1117636108
10.1016/j.schres.2007.11.009
10.1038/tp.2017.174
10.1152/jn.1992.67.1.145
10.1016/j.biopsych.2004.01.018
10.1038/s41380-018-0042-4
10.1016/j.tics.2018.12.001
10.1371/journal.pcbi.1006319
10.1016/j.biopsych.2008.12.007
10.1001/archgenpsychiatry.2010.77
10.1523/JNEUROSCI.3839-08.2008
10.1523/JNEUROSCI.0909-12.2012
10.1038/sj.npp.1300730
10.1098/rstb.2013.0481
10.1176/appi.ajp.160.1.13
10.1093/schbul/sbu105
10.1001/archgenpsychiatry.2012.169
10.1093/oxfordjournals.schbul.a007038
10.1162/neco_a_01023
10.1152/jn.1994.72.2.1024
10.1016/S0166-4328(98)00102-8
10.1093/schbul/sbv190
10.1073/pnas.91.24.11651
10.1016/j.neuron.2016.04.019
10.1016/S0306-4522(00)00019-1
10.1038/sj.mp.4002058
10.1038/nrn3289
10.1016/S2215-0366(18)30268-2
10.1016/j.biopsych.2008.12.016
10.1016/j.tics.2009.04.005
10.1007/s00213-006-0405-4
10.3389/fncom.2015.00136
10.1038/sj.npp.1301437
10.1016/j.biopsych.2011.10.009
10.1093/schbul/sbs107
10.1111/j.1471-4159.1989.tb09224.x
10.1001/archpsyc.63.6.611
10.1016/S0165-0173(98)00019-8
10.3389/fnhum.2010.00239
10.1016/j.neuroimage.2018.05.074
10.1098/rstb.2008.0152
10.1002/wps.20526
10.1093/schbul/sbt134
10.1038/nature02581
10.1038/nrn.2015.26
10.1016/j.tins.2009.02.005
10.1093/schbul/sbi060
10.1016/j.schres.2016.06.005
10.1016/j.biopsych.2016.05.021
10.1002/wps.20213
10.3346/jkms.2001.16.1.88
10.1038/nature05051
10.1176/appi.ajp.2010.10020165
10.1016/j.biopsych.2013.02.029
10.1001/archgenpsychiatry.2010.10
10.1038/s41386-018-0056-2
10.3389/fnhum.2016.00502
10.1093/schbul/sby076
10.3389/fpsyt.2018.00187
10.1001/archpsyc.63.12.1386
10.1038/s41598-019-50138-8
10.1016/j.euroneuro.2019.06.004
10.1016/S2215-0366(14)70275-5
10.1093/schbul/sbs050
10.1002/hbm.23480
10.1177/0269881116650087
10.1503/jpn.090169
10.1001/jamapsychiatry.2016.1135
10.1001/archgenpsychiatry.2010.169
10.3389/fnbeh.2014.00382
10.1038/npp.2008.214
10.1016/S0924-9338(02)00628-4
10.1192/bjp.bp.113.138578
10.1093/brain/awt264
10.1038/mp.2011.75
10.1016/j.psyneuen.2014.03.010
10.1126/science.aan3458
10.3389/fnhum.2010.00215
10.1001/archgenpsychiatry.2008.514
10.1038/npp.2013.347
10.1523/JNEUROSCI.1778-13.2013
10.1038/tp.2016.278
10.1503/jpn.110181
10.1038/s41562-017-0129
10.1038/sj.npp.1301373
10.1176/appi.ajp.2011.11010160
10.1016/j.cub.2017.12.059
10.1016/j.schres.2015.04.036
10.1016/j.biopsych.2012.02.007
10.1523/JNEUROSCI.20-06-02369.2000
10.3389/fnhum.2015.00521
ContentType Journal Article
Copyright 2020 Society of Biological Psychiatry
Society of Biological Psychiatry
Copyright © 2020 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
Copyright_xml – notice: 2020 Society of Biological Psychiatry
– notice: Society of Biological Psychiatry
– notice: Copyright © 2020 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
DOI 10.1016/j.biopsych.2020.03.012
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList
MEDLINE - Academic

MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Biology
EISSN 1873-2402
EndPage 314
ExternalDocumentID 32430200
10_1016_j_biopsych_2020_03_012
S0006322320313834
1_s2_0_S0006322320313834
Genre Review
Research Support, Non-U.S. Gov't
Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: Medical Research Council
  grantid: MC_PC_17214
– fundername: Medical Research Council
  grantid: MR/S007806/1
– fundername: Wellcome Trust
  grantid: 094849/Z/10/Z
– fundername: Medical Research Council
  grantid: MR/T045302/1
GroupedDBID ---
--K
--M
-DZ
.1-
.FO
.~1
0R~
1B1
1P~
1RT
1~.
1~5
23N
4.4
457
4G.
5GY
5RE
5VS
6J9
7-5
71M
8P~
9JM
AABNK
AAEDT
AAEDW
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AATTM
AAXKI
AAXLA
AAXUO
AAYWO
ABBQC
ABCQJ
ABCQX
ABFNM
ABFRF
ABIVO
ABJNI
ABLJU
ABMAC
ABMZM
ACDAQ
ACGFO
ACIEU
ACIUM
ACNCT
ACRLP
ACVFH
ADBBV
ADCNI
ADEZE
AEBSH
AEFWE
AEIPS
AEKER
AENEX
AEUPX
AEVXI
AFPUW
AFRHN
AFTJW
AFXIZ
AGCQF
AGHFR
AGUBO
AGWIK
AGYEJ
AIEXJ
AIIUN
AIKHN
AITUG
AJRQY
AJUYK
AKBMS
AKRWK
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
ANKPU
ANZVX
APXCP
AXJTR
BKOJK
BLXMC
BNPGV
CS3
DU5
EBS
EFJIC
EFKBS
EO8
EO9
EP2
EP3
F5P
FDB
FIRID
FNPLU
FYGXN
G-Q
GBLVA
IHE
J1W
KOM
L7B
M29
M2V
M39
M41
MO0
MOBAO
N9A
O-L
O9-
OAUVE
OH0
OU-
OZT
P-8
P-9
P2P
PC.
Q38
ROL
RPZ
SAE
SCC
SDF
SDG
SDP
SEL
SES
SPCBC
SSH
SSN
SSZ
T5K
UNMZH
UPT
UV1
WH7
Z5R
ZCA
~G-
.GJ
3O-
53G
AAQXK
ABDPE
ABWVN
ABXDB
ACRPL
ADMUD
ADNMO
AFFNX
AFJKZ
AGQPQ
AHHHB
AIGII
ASPBG
AVWKF
AZFZN
EFLBG
EJD
FEDTE
FGOYB
G-2
HEG
HMK
HMO
HMQ
HVGLF
HZ~
H~9
R2-
SNS
UAP
WUQ
XJT
XOL
ZGI
ZKB
ZXP
~HD
AACTN
AADPK
AAIAV
ABLVK
ABYKQ
AFCTW
AFKWA
AJOXV
AMFUW
LCYCR
ZA5
AAYXX
CITATION
AGRNS
CGR
CUY
CVF
ECM
EIF
NPM
7X8
ACLOT
ID FETCH-LOGICAL-c544t-31c729a1f731e489e8870b86e176aaefeec0609fb102fc77b79ec54b8a0a10b3
IEDL.DBID AIKHN
ISSN 0006-3223
1873-2402
IngestDate Thu Sep 25 09:02:40 EDT 2025
Mon Jul 21 06:06:30 EDT 2025
Thu Apr 24 23:12:47 EDT 2025
Thu Sep 18 00:16:21 EDT 2025
Fri Feb 23 02:46:42 EST 2024
Sat Sep 20 19:12:28 EDT 2025
Tue Aug 26 17:00:49 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords Psychosis
Schizophrenia
Prodrome
Risk
Computational psychiatry
Imaging
Language English
License Copyright © 2020 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c544t-31c729a1f731e489e8870b86e176aaefeec0609fb102fc77b79ec54b8a0a10b3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ORCID 0000-0002-2928-1972
0000-0002-7661-8881
0000-0001-6599-7292
PMID 32430200
PQID 2405305686
PQPubID 23479
PageCount 11
ParticipantIDs proquest_miscellaneous_2405305686
pubmed_primary_32430200
crossref_citationtrail_10_1016_j_biopsych_2020_03_012
crossref_primary_10_1016_j_biopsych_2020_03_012
elsevier_sciencedirect_doi_10_1016_j_biopsych_2020_03_012
elsevier_clinicalkeyesjournals_1_s2_0_S0006322320313834
elsevier_clinicalkey_doi_10_1016_j_biopsych_2020_03_012
PublicationCentury 2000
PublicationDate 2020-08-15
PublicationDateYYYYMMDD 2020-08-15
PublicationDate_xml – month: 08
  year: 2020
  text: 2020-08-15
  day: 15
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Biological psychiatry (1969)
PublicationTitleAlternate Biol Psychiatry
PublicationYear 2020
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Beedie, St. Clair, Benson (bib96) 2011; 36
Mirenowicz, Schultz (bib4) 1994; 72
Jensen, Willeit, Zipursky, Savina, Smith, Menon (bib30) 2008; 33
Corlett, Honey, Fletcher (bib70) 2016; 30
Chen, Lee, Yeh, Chiu, Chen, Yang (bib64) 2012; 201
Egerton, Valmaggia, Howes, Day, Chaddock, Allen (bib122) 2016; 176
Lataster, Myin-Germeys, Lieb, Wittchen, van Os (bib108) 2012; 125
Egerton, Chaddock, Winton-Brown, Bloomfield, Bhattacharyya, Allen (bib59) 2013; 74
Sariaslan, Larsson, D’Onofrio, Långström, Fazel, Lichtenstein (bib109) 2015; 41
Abi-Dargham, van de Giessen, Slifstein, Kegeles, Laruelle (bib47) 2009; 65
Zenon, Filali, Duhamel, Olivier (bib126) 2010; 22
Katthagen, Mathys, Deserno, Walter, Kathmann, Heinz, Schlagenhauf (bib39) 2018; 14
Krabbendam, Van Os (bib111) 2005; 31
Cassidy, Balsam, Weinstein, Rosengard, Slifstein, Daw (bib97) 2018; 28
Brischoux, Chakraborty, Brierley, Ungless (bib10) 2009; 106
Mikhael, Kim, Uchida, Gershman (bib24) 2019
Mizrahi, Addington, Rusjan, Suridjan, Ng, Boileau (bib46) 2012; 71
Egerton, Howes, Houle, McKenzie, Valmaggia, Bagby (bib121) 2017; 43
Cathy, Cipriani, Ioannidis, Radua, Stahl, Provenzani (bib142) 2018; 17
Gershman (bib26) 2017; 29
Brunelin, d’Amato, van Os, Cochet, Suaud-Chagny, Saoud (bib119) 2008; 100
Corlett, Horga, Fletcher, Alderson-Day, Schmack, Powers (bib94) 2019; 23
Berridge, Robinson (bib73) 1998; 28
Bromberg-Martin, Matsumoto, Hikosaka (bib11) 2010; 68
Millman, Gallagher, Demro, Schiffman, Reeves, Gold (bib78) 2019
Lak, Nomoto, Keramati, Sakagami, Kepecs (bib21) 2017; 27
Roiser, Howes, Chaddock, Joyce, McGuire (bib82) 2013; 39
Lancaster, Linden, Tansey, Banaschewski, Bokde, Bromberg (bib85) 2016; 73
Adams, Stephan, Brown, Frith, Friston (bib28) 2013; 4
Dang, O’Neil, Jagust (bib137) 2012; 32
Lloyd, Dayan (bib23) 2015; 11
Vilares, Kording (bib19) 2017; 1
Corcoran, Walker, Huot, Mittal, Tessner, Kestler, Aalaspina (bib120) 2003; 29
Winton-Brown, Schmidt, Roiser, Howes, Egerton, Fusar-Poli (bib77) 2017; 7
Wand, Oswald, McCaul, Wong, Johnson, Zhou (bib118) 2007; 32
Modinos, Allen, Zugman, Dima, Azis, Samson (bib83) 2020; 46
Day, Valmaggia, Mondelli, Papadopoulos, Papadopoulos, Pariante, McGuire (bib115) 2014; 158
Fiorillo, Tobler, Schultz (bib145) 2003; 299
Powers, Mathys, Corlett (bib98) 2017; 357
de Lafuente, Romo (bib20) 2011; 108
Sterzer, Adams, Fletcher, Frith, Lawrie, Muckli (bib86) 2018; 84
Cantor-Graae, Selten (bib110) 2005; 162
Kirschner, Hager, Muff, Bischof, Hartmann-Riemer, Kluge (bib84) 2018; 44
Kapur (bib71) 2003; 160
Feldman, Friston (bib93) 2010; 4
Howes, Kapur (bib105) 2009; 35
Howes, Murray (bib68) 2014; 383
McCutcheon, Reis Marques, Howes (bib134) 2019
Fitzgerald, Dolan, Friston (bib17) 2015; 9
Corlett, Murray, Honey, Aitken, Shanks, Robbins (bib29) 2007; 130
Schultz (bib14) 2016; 17
Ćurčić-Blake, Liemburg, Vercammen, Swart, Knegtering, Bruggeman, Aleman (bib99) 2013; 39
Guarraci, Kapp (bib6) 1999; 99
Abercrombie, Keefe, DiFrischia, Zigmond (bib123) 1989; 52
Seymour, O’Doherty, Dayan, Koltzenburg, Jones, Dolan (bib3) 2004; 429
Tagore, Schifani, Rao, Tseng, Zakzanis, Rusjan (bib135) 2019; 29
Selten, Van Der Ven, Rutten, Cantor-Graae (bib104) 2013; 39
Nour, Dahoun, Schwartenbeck, Adams, FitzGerald, Coello (bib15) 2018; 115
Bach, Dolan (bib16) 2012; 13
Fusar-Poli, Howes, Allen, Broome, Valli, Asselin (bib62) 2010; 67
Corlett, Frith, Fletcher (bib88) 2009; 206
Rebec (bib12) 1998; 22
Schlagenhauf, Sterzer, Schmack, Ballmaier, Rapp, Wrase (bib33) 2009; 65
Howes, Kambeitz, Kim, Stahl, Slifstein, Abi-Dargham, Kapur (bib44) 2012; 69
Howes, Bose, Turkheimer, Valli, Egerton, Stahl (bib58) 2011; 16
Howes, McCutcheon, Owen, Murray (bib107) 2017; 81
Bloemen, de Koning, Gleich, Meijer, de Haan, Linszen (bib60) 2012; 23
Smieskova, Roiser, Chaddock, Schmidt, Harrisberger, Bendfeldt (bib81) 2015; 166
Horga, Schatz, Abi-Dargham, Peterson (bib100) 2014; 34
Horvitz (bib13) 2000; 96
Kim, Hwu, Zhang, Lu, Park, Hwang (bib106) 2001; 16
Heinz, Schlagenhauf (bib101) 2010; 36
Anstrom, Woodward (bib9) 2005; 30
Jauhar, Veronese, Nour, Rogdaki, Hathway, Turkheimer (bib67) 2019; 24
Jauhar, Nour, Veronese, Rogdaki, Bonoldi, Azis (bib54) 2017; 74
Abi-Dargham, Kegeles, Zea-Ponce, Mawlawi, Martinez, Mitropoulou (bib52) 2004; 55
Mirza, Adams, Friston, Parr (bib95) 2019; 9
Heinz (bib72) 2002; 17
Corlett, Fletcher (bib103) 2012; 50
Diaconescu, Jensen, Wang, Willeit, Menon, Kapur, McIntosh (bib38) 2011; 4
Song, Lee (bib25) 2019
Reininghaus, Kempton, Valmaggia, Craig, Garety, Onyejiaka (bib114) 2016; 42
Maia, Frank (bib69) 2016; 81
Wotruba, Heekeren, Michels, Buechle, Simon, Theodoridou (bib76) 2014; 8
Ermakova, Knolle, Justicia, Bullmore, Jones, Robbins (bib79) 2018; 43
Corlett, Honey, Fletcher (bib127) 2007; 21
Friston, Stephan, Montague, Dolan (bib89) 2014; 1
Düzel, Bunzeck, Guitart-Masip, Wittmann, Schott, Tobler (bib43) 2009; 32
Schmack, Rössler, Sekutowicz, Brandl, Müller, Petrovic, Sterzer (bib102) 2015; 9
Nestler EJ, Human SE, Malenka RC (2014): Widely projecting systems: Monoamines, acetylcholine, and orexin. In: Sydor A, Brown RY, editors. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, 3rd ed. New York: McGraw-Hill, pp 147–148, 154–157.
Howes, McCutcheon (bib139) 2017; 7
Howes, Williams, Ibrahim, Leung, Egerton, McGuire, Turkheimer (bib48) 2013; 136
Sterzer, Voss, Schlagenhauf, Heinz (bib92) 2019; 190
Waltz, Schweitzer, Gold, Kurup, Ross, Salmeron (bib34) 2009; 34
Corlett, Honey, Aitken, Dickinson, Shanks, Absalom (bib128) 2006; 63
Romaniuk, Honey, King, Whalley, McIntosh, Levita (bib31) 2010; 67
Schmack, Gomez-Carrillo de Castro, Rothkirch, Sekutowicz, Rossler, Haynes (bib129) 2013; 33
Nielsen, Rostrup, Wulff, Bak, Lublin, Kapur, Glenthøj (bib41) 2012; 71
Kaar, Natesan, McCutcheon, Howes (bib144) 2019; 9
Schultz, Dayan, Montague (bib2) 1997; 275
Diederen, Spencer, Vestergaard, Fletcher, Schultz (bib27) 2016; 90
Cullen, Zunszain, Dickson, Roberts, Fisher, Pariante, Laurens (bib116) 2014; 46
Abi-Dargham, Rodenhiser, Printz, Zea-Ponce, Gil, Kegeles (bib51) 2000; 97
Pessiglione, Seymour, Flandin, Dolan, Frith (bib7) 2006; 442
Mizrahi, Kenk, Suridjan, Boileau, George, McKenzie (bib66) 2014; 39
Schmack, Rothkirch, Priller, Sterzer (bib130) 2017; 38
Schmidt, Antoniades, Allen, Egerton, Chaddock, Borgwardt (bib80) 2017; 47
Reith, Benkelfat, Sherwin, Yasuhara, Kuwabara, Andermann (bib53) 1994; 91
Björklund, Dunnett (bib55) 2007; 30
McCutcheon, Abi-Dargham, Howes (bib56) 2019; 42
Howes, Montgomery, Asselin, Murray, Valli, Tabraham (bib57) 2009; 66
Suridjan, Rusjan, Addington, Wilson, Houle, Mizrahi (bib61) 2013; 38
Mishara, Sterzer (bib91) 2015; 14
Varese, Smeets, Drukker, Lieverse, Lataster, Viechtbauer (bib112) 2012; 38
Tseng, Watts, Kiang, Suridjan, Wilson, Houle (bib45) 2018; 44
Howes, Bose, Turkheimer, Valli, Egerton, Valmaggia (bib63) 2011; 168
Fusar-Poli, Howes, Allen, Broome, Valli, Asselin (bib131) 2011; 16
Moran, Tagamets, Sampath, O’Donnell, Stein, Kochunov, Hong (bib138) 2013; 74
McCutcheon, Beck, Jauhar, Howes (bib49) 2018; 44
Morris, Vercammen, Lenroot, Moore, Langton, Short (bib40) 2012; 17
Friston, Schwartenbeck, FitzGerald, Moutoussis, Behrens, Dolan (bib18) 2014; 369
Ljungberg, Apicella, Schultz (bib5) 1992; 67
Gradin, Waiter, O’Connor, Romaniuk, Stickle, Matthews (bib35) 2013; 211
Juckel, Schlagenhauf, Koslowski, Wüstenberg, Villringer, Knutson (bib32) 2006; 29
Boileau, Dagher, Leyton, Gunn, Baker, Diksic, Benkelfat (bib124) 2006; 63
Lodge, Grace (bib136) 2011; 29
Van Der Gaag, Smit, Bechdolf, French, Linszen, Yung (bib143) 2013; 149
Radua, Schmidt, Borgwardt, Heinz, Schlagenhauf, McGuire, Fusar-Poli (bib74) 2015; 72
Woodward, Cowan, Park, Ansari, Baldwin, Li (bib65) 2011; 168
Schultz, Preuschoff, Camerer, Hsu, Fiorillo, Tobler, Bossaerts (bib22) 2008; 363
Waltz, Schweitzer, Ross, Kurup, Salmeron, Rose (bib37) 2010; 35
Jauhar, McCutcheon, Borgan, Veronese, Nour, Pepper (bib140) 2018; 5
Davies, Radua, Cipriani, Stahl, Provenzani, McGuire, Fusar-Poli (bib141) 2018; 9
Sterzer, Mishara, Voss, Heinz (bib90) 2016; 10
Murray, Corlett, Clark, Pessiglione, Blackwell, Honey (bib36) 2008; 13
Kegeles, Abi-Dargham, Frankle, Gil, Cooper, Slifstein (bib50) 2010; 67
Friston (bib87) 2009; 13
Walker, Trotman, Pearce, Addington, Cadenhead, Cornblatt (bib117) 2013; 74
Howes, Kapur (bib113) 2014; 205
Juckel, Friedel, Koslowski, Witthaus, Özgürdal, Gudlowski (bib75) 2012; 66
Slifstein, van de Giessen, Van Snellenberg, Thompson, Narendran, Gil (bib132) 2015; 72
Rao, Northoff, Tagore, Rusjan, Kenk, Wilson (bib133) 2018; 45
Haber, Fudge, McFarland (bib1) 2000; 20
Joshua, Adler, Mitelman, Vaadia, Bergman (bib8) 2008; 28
Juckel, Schlagenhauf, Koslowski, Filonov, Wüstenberg, Villringer (bib42) 2006; 187
Juckel (10.1016/j.biopsych.2020.03.012_bib32) 2006; 29
Mirza (10.1016/j.biopsych.2020.03.012_bib95) 2019; 9
Fiorillo (10.1016/j.biopsych.2020.03.012_bib145) 2003; 299
Düzel (10.1016/j.biopsych.2020.03.012_bib43) 2009; 32
Cassidy (10.1016/j.biopsych.2020.03.012_bib97) 2018; 28
Schlagenhauf (10.1016/j.biopsych.2020.03.012_bib33) 2009; 65
Egerton (10.1016/j.biopsych.2020.03.012_bib122) 2016; 176
Seymour (10.1016/j.biopsych.2020.03.012_bib3) 2004; 429
Abi-Dargham (10.1016/j.biopsych.2020.03.012_bib52) 2004; 55
Fusar-Poli (10.1016/j.biopsych.2020.03.012_bib131) 2011; 16
Pessiglione (10.1016/j.biopsych.2020.03.012_bib7) 2006; 442
Waltz (10.1016/j.biopsych.2020.03.012_bib37) 2010; 35
Fitzgerald (10.1016/j.biopsych.2020.03.012_bib17) 2015; 9
Horga (10.1016/j.biopsych.2020.03.012_bib100) 2014; 34
Juckel (10.1016/j.biopsych.2020.03.012_bib75) 2012; 66
Van Der Gaag (10.1016/j.biopsych.2020.03.012_bib143) 2013; 149
Mizrahi (10.1016/j.biopsych.2020.03.012_bib66) 2014; 39
Sterzer (10.1016/j.biopsych.2020.03.012_bib86) 2018; 84
Slifstein (10.1016/j.biopsych.2020.03.012_bib132) 2015; 72
Abi-Dargham (10.1016/j.biopsych.2020.03.012_bib47) 2009; 65
Gradin (10.1016/j.biopsych.2020.03.012_bib35) 2013; 211
Beedie (10.1016/j.biopsych.2020.03.012_bib96) 2011; 36
Vilares (10.1016/j.biopsych.2020.03.012_bib19) 2017; 1
Katthagen (10.1016/j.biopsych.2020.03.012_bib39) 2018; 14
Howes (10.1016/j.biopsych.2020.03.012_bib113) 2014; 205
Corlett (10.1016/j.biopsych.2020.03.012_bib94) 2019; 23
Lloyd (10.1016/j.biopsych.2020.03.012_bib23) 2015; 11
Abi-Dargham (10.1016/j.biopsych.2020.03.012_bib51) 2000; 97
Modinos (10.1016/j.biopsych.2020.03.012_bib83) 2020; 46
Feldman (10.1016/j.biopsych.2020.03.012_bib93) 2010; 4
McCutcheon (10.1016/j.biopsych.2020.03.012_bib56) 2019; 42
Friston (10.1016/j.biopsych.2020.03.012_bib18) 2014; 369
Diaconescu (10.1016/j.biopsych.2020.03.012_bib38) 2011; 4
Kapur (10.1016/j.biopsych.2020.03.012_bib71) 2003; 160
Woodward (10.1016/j.biopsych.2020.03.012_bib65) 2011; 168
Friston (10.1016/j.biopsych.2020.03.012_bib87) 2009; 13
Howes (10.1016/j.biopsych.2020.03.012_bib57) 2009; 66
Sariaslan (10.1016/j.biopsych.2020.03.012_bib109) 2015; 41
Guarraci (10.1016/j.biopsych.2020.03.012_bib6) 1999; 99
Rao (10.1016/j.biopsych.2020.03.012_bib133) 2018; 45
Juckel (10.1016/j.biopsych.2020.03.012_bib42) 2006; 187
Lancaster (10.1016/j.biopsych.2020.03.012_bib85) 2016; 73
Horvitz (10.1016/j.biopsych.2020.03.012_bib13) 2000; 96
Tseng (10.1016/j.biopsych.2020.03.012_bib45) 2018; 44
Jauhar (10.1016/j.biopsych.2020.03.012_bib54) 2017; 74
Chen (10.1016/j.biopsych.2020.03.012_bib64) 2012; 201
Schmidt (10.1016/j.biopsych.2020.03.012_bib80) 2017; 47
Schultz (10.1016/j.biopsych.2020.03.012_bib2) 1997; 275
Egerton (10.1016/j.biopsych.2020.03.012_bib59) 2013; 74
Howes (10.1016/j.biopsych.2020.03.012_bib48) 2013; 136
Varese (10.1016/j.biopsych.2020.03.012_bib112) 2012; 38
Haber (10.1016/j.biopsych.2020.03.012_bib1) 2000; 20
Corlett (10.1016/j.biopsych.2020.03.012_bib103) 2012; 50
Egerton (10.1016/j.biopsych.2020.03.012_bib121) 2017; 43
Gershman (10.1016/j.biopsych.2020.03.012_bib26) 2017; 29
Schmack (10.1016/j.biopsych.2020.03.012_bib129) 2013; 33
Ljungberg (10.1016/j.biopsych.2020.03.012_bib5) 1992; 67
Corlett (10.1016/j.biopsych.2020.03.012_bib70) 2016; 30
Fusar-Poli (10.1016/j.biopsych.2020.03.012_bib62) 2010; 67
Heinz (10.1016/j.biopsych.2020.03.012_bib72) 2002; 17
McCutcheon (10.1016/j.biopsych.2020.03.012_bib134) 2019
Roiser (10.1016/j.biopsych.2020.03.012_bib82) 2013; 39
Sterzer (10.1016/j.biopsych.2020.03.012_bib90) 2016; 10
Howes (10.1016/j.biopsych.2020.03.012_bib58) 2011; 16
Heinz (10.1016/j.biopsych.2020.03.012_bib101) 2010; 36
Mizrahi (10.1016/j.biopsych.2020.03.012_bib46) 2012; 71
Maia (10.1016/j.biopsych.2020.03.012_bib69) 2016; 81
Wotruba (10.1016/j.biopsych.2020.03.012_bib76) 2014; 8
Abercrombie (10.1016/j.biopsych.2020.03.012_bib123) 1989; 52
Zenon (10.1016/j.biopsych.2020.03.012_bib126) 2010; 22
Lataster (10.1016/j.biopsych.2020.03.012_bib108) 2012; 125
Nielsen (10.1016/j.biopsych.2020.03.012_bib41) 2012; 71
Kim (10.1016/j.biopsych.2020.03.012_bib106) 2001; 16
Howes (10.1016/j.biopsych.2020.03.012_bib139) 2017; 7
Sterzer (10.1016/j.biopsych.2020.03.012_bib92) 2019; 190
Radua (10.1016/j.biopsych.2020.03.012_bib74) 2015; 72
Powers (10.1016/j.biopsych.2020.03.012_bib98) 2017; 357
Dang (10.1016/j.biopsych.2020.03.012_bib137) 2012; 32
Mirenowicz (10.1016/j.biopsych.2020.03.012_bib4) 1994; 72
Song (10.1016/j.biopsych.2020.03.012_bib25) 2019
Cantor-Graae (10.1016/j.biopsych.2020.03.012_bib110) 2005; 162
Friston (10.1016/j.biopsych.2020.03.012_bib89) 2014; 1
Bromberg-Martin (10.1016/j.biopsych.2020.03.012_bib11) 2010; 68
Schultz (10.1016/j.biopsych.2020.03.012_bib22) 2008; 363
Day (10.1016/j.biopsych.2020.03.012_bib115) 2014; 158
Corlett (10.1016/j.biopsych.2020.03.012_bib128) 2006; 63
Adams (10.1016/j.biopsych.2020.03.012_bib28) 2013; 4
Winton-Brown (10.1016/j.biopsych.2020.03.012_bib77) 2017; 7
Krabbendam (10.1016/j.biopsych.2020.03.012_bib111) 2005; 31
Waltz (10.1016/j.biopsych.2020.03.012_bib34) 2009; 34
10.1016/j.biopsych.2020.03.012_bib125
Ćurčić-Blake (10.1016/j.biopsych.2020.03.012_bib99) 2013; 39
Anstrom (10.1016/j.biopsych.2020.03.012_bib9) 2005; 30
Suridjan (10.1016/j.biopsych.2020.03.012_bib61) 2013; 38
Nour (10.1016/j.biopsych.2020.03.012_bib15) 2018; 115
Schmack (10.1016/j.biopsych.2020.03.012_bib102) 2015; 9
Corcoran (10.1016/j.biopsych.2020.03.012_bib120) 2003; 29
Mishara (10.1016/j.biopsych.2020.03.012_bib91) 2015; 14
Boileau (10.1016/j.biopsych.2020.03.012_bib124) 2006; 63
Joshua (10.1016/j.biopsych.2020.03.012_bib8) 2008; 28
Brischoux (10.1016/j.biopsych.2020.03.012_bib10) 2009; 106
Smieskova (10.1016/j.biopsych.2020.03.012_bib81) 2015; 166
Davies (10.1016/j.biopsych.2020.03.012_bib141) 2018; 9
Kaar (10.1016/j.biopsych.2020.03.012_bib144) 2019; 9
Corlett (10.1016/j.biopsych.2020.03.012_bib29) 2007; 130
Cullen (10.1016/j.biopsych.2020.03.012_bib116) 2014; 46
de Lafuente (10.1016/j.biopsych.2020.03.012_bib20) 2011; 108
Corlett (10.1016/j.biopsych.2020.03.012_bib127) 2007; 21
Walker (10.1016/j.biopsych.2020.03.012_bib117) 2013; 74
Jensen (10.1016/j.biopsych.2020.03.012_bib30) 2008; 33
Howes (10.1016/j.biopsych.2020.03.012_bib63) 2011; 168
Morris (10.1016/j.biopsych.2020.03.012_bib40) 2012; 17
Millman (10.1016/j.biopsych.2020.03.012_bib78) 2019
Tagore (10.1016/j.biopsych.2020.03.012_bib135) 2019; 29
Kirschner (10.1016/j.biopsych.2020.03.012_bib84) 2018; 44
Corlett (10.1016/j.biopsych.2020.03.012_bib88) 2009; 206
Bach (10.1016/j.biopsych.2020.03.012_bib16) 2012; 13
Ermakova (10.1016/j.biopsych.2020.03.012_bib79) 2018; 43
Cathy (10.1016/j.biopsych.2020.03.012_bib142) 2018; 17
Rebec (10.1016/j.biopsych.2020.03.012_bib12) 1998; 22
Howes (10.1016/j.biopsych.2020.03.012_bib107) 2017; 81
Selten (10.1016/j.biopsych.2020.03.012_bib104) 2013; 39
Lak (10.1016/j.biopsych.2020.03.012_bib21) 2017; 27
Brunelin (10.1016/j.biopsych.2020.03.012_bib119) 2008; 100
Jauhar (10.1016/j.biopsych.2020.03.012_bib67) 2019; 24
Diederen (10.1016/j.biopsych.2020.03.012_bib27) 2016; 90
Bloemen (10.1016/j.biopsych.2020.03.012_bib60) 2012; 23
Mikhael (10.1016/j.biopsych.2020.03.012_bib24) 2019
Reith (10.1016/j.biopsych.2020.03.012_bib53) 1994; 91
Moran (10.1016/j.biopsych.2020.03.012_bib138) 2013; 74
Björklund (10.1016/j.biopsych.2020.03.012_bib55) 2007; 30
Schmack (10.1016/j.biopsych.2020.03.012_bib130) 2017; 38
Romaniuk (10.1016/j.biopsych.2020.03.012_bib31) 2010; 67
Berridge (10.1016/j.biopsych.2020.03.012_bib73) 1998; 28
Reininghaus (10.1016/j.biopsych.2020.03.012_bib114) 2016; 42
Wand (10.1016/j.biopsych.2020.03.012_bib118) 2007; 32
Howes (10.1016/j.biopsych.2020.03.012_bib105) 2009; 35
Jauhar (10.1016/j.biopsych.2020.03.012_bib140) 2018; 5
Kegeles (10.1016/j.biopsych.2020.03.012_bib50) 2010; 67
Howes (10.1016/j.biopsych.2020.03.012_bib44) 2012; 69
Lodge (10.1016/j.biopsych.2020.03.012_bib136) 2011; 29
Schultz (10.1016/j.biopsych.2020.03.012_bib14) 2016; 17
Howes (10.1016/j.biopsych.2020.03.012_bib68) 2014; 383
Murray (10.1016/j.biopsych.2020.03.012_bib36) 2008; 13
McCutcheon (10.1016/j.biopsych.2020.03.012_bib49) 2018; 44
References_xml – volume: 299
  start-page: 1898
  year: 2003
  end-page: 1902
  ident: bib145
  article-title: Discrete coding of reward probability and uncertainty by dopamine neurons
  publication-title: Science
– volume: 72
  start-page: 1024
  year: 1994
  end-page: 1027
  ident: bib4
  article-title: Importance of unpredictability for reward responses in primate dopamine neurons
  publication-title: J Neurophysiol
– volume: 9
  start-page: 187
  year: 2018
  ident: bib141
  article-title: Efficacy and acceptability of interventions for attenuated positive psychotic symptoms in individuals at clinical high risk of psychosis: A network meta-analysis
  publication-title: Front Psychiatry
– volume: 43
  start-page: 1691
  year: 2018
  end-page: 1699
  ident: bib79
  article-title: Abnormal reward prediction-error signalling in antipsychotic naive individuals with first-episode psychosis or clinical risk for psychosis
  publication-title: Neuropsychopharmacology
– volume: 46
  start-page: 1
  year: 2014
  end-page: 13
  ident: bib116
  article-title: Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
  publication-title: Psychoneuroendocrinology
– volume: 160
  start-page: 13
  year: 2003
  end-page: 23
  ident: bib71
  article-title: Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia
  publication-title: Am J Psychiatry
– volume: 28
  start-page: 309
  year: 1998
  end-page: 369
  ident: bib73
  article-title: What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
  publication-title: Brain Res Rev
– reference: Nestler EJ, Human SE, Malenka RC (2014): Widely projecting systems: Monoamines, acetylcholine, and orexin. In: Sydor A, Brown RY, editors. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, 3rd ed. New York: McGraw-Hill, pp 147–148, 154–157.
– volume: 30
  start-page: 1832
  year: 2005
  end-page: 1840
  ident: bib9
  article-title: Restraint increases dopaminergic burst firing in awake rats
  publication-title: Neuropsychopharmacology
– volume: 9
  start-page: 1
  year: 2015
  end-page: 16
  ident: bib17
  article-title: Dopamine, reward learning, and active inference
  publication-title: Front Comput Neurosci
– volume: 16
  start-page: 885
  year: 2011
  end-page: 886
  ident: bib58
  article-title: Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: A PET study
  publication-title: Mol Psychiatry
– volume: 33
  start-page: 473
  year: 2008
  end-page: 479
  ident: bib30
  article-title: The formation of abnormal associations in schizophrenia: Neural and behavioral evidence
  publication-title: Neuropsychopharmacology
– volume: 32
  start-page: 2310
  year: 2007
  end-page: 2320
  ident: bib118
  article-title: Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress
  publication-title: Neuropsychopharmacology
– volume: 11
  start-page: 1
  year: 2015
  end-page: 34
  ident: bib23
  article-title: Tamping ramping: Algorithmic, implementational, and computational explanations of phasic dopamine signals in the accumbens
  publication-title: PLoS Comput Biol
– volume: 38
  start-page: 1767
  year: 2017
  end-page: 1779
  ident: bib130
  article-title: Enhanced predictive signalling in schizophrenia
  publication-title: Hum Brain Mapp
– volume: 35
  start-page: 549
  year: 2009
  end-page: 562
  ident: bib105
  article-title: The dopamine hypothesis of schizophrenia: Version III—the final common pathway
  publication-title: Schizophr Bull
– volume: 30
  start-page: 194
  year: 2007
  end-page: 202
  ident: bib55
  article-title: Dopamine neuron systems in the brain: An update
  publication-title: Trends Neurosci
– volume: 36
  start-page: 150
  year: 2011
  end-page: 164
  ident: bib96
  article-title: Atypical scanpaths in schizophrenia: Evidence of a trait- or state-dependent phenomenon?
  publication-title: J Psychiatry Neurosci
– volume: 100
  start-page: 206
  year: 2008
  end-page: 211
  ident: bib119
  article-title: Effects of acute metabolic stress on the dopaminergic and pituitary–adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls
  publication-title: Schizophr Res
– volume: 44
  start-page: 542
  year: 2018
  end-page: 551
  ident: bib45
  article-title: Nigral stress-induced dopamine release in clinical high risk and antipsychotic-naïve schizophrenia
  publication-title: Schizophr Bull
– volume: 357
  start-page: 596
  year: 2017
  end-page: 600
  ident: bib98
  article-title: Pavlovian conditioning–induced hallucinations result from overweighting of perceptual priors
  publication-title: Science
– volume: 29
  start-page: 409
  year: 2006
  end-page: 416
  ident: bib32
  article-title: Dysfunction of ventral striatal reward prediction in schizophrenia
  publication-title: Neuroimage
– volume: 74
  start-page: 106
  year: 2013
  end-page: 112
  ident: bib59
  article-title: Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort
  publication-title: Biol Psychiatry
– volume: 52
  start-page: 1655
  year: 1989
  end-page: 1658
  ident: bib123
  article-title: Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens, and medial frontal cortex
  publication-title: J Neurochem
– volume: 20
  start-page: 2369
  year: 2000
  end-page: 2382
  ident: bib1
  article-title: Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum
  publication-title: J Neurosci
– volume: 206
  start-page: 515
  year: 2009
  end-page: 530
  ident: bib88
  article-title: From drugs to deprivation: A Bayesian framework for understanding models of psychosis
  publication-title: Psychopharmacology (Berl)
– volume: 166
  start-page: 17
  year: 2015
  end-page: 23
  ident: bib81
  article-title: Modulation of motivational salience processing during the early stages of psychosis
  publication-title: Schizophr Res
– volume: 72
  start-page: 316
  year: 2015
  end-page: 324
  ident: bib132
  article-title: Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia
  publication-title: JAMA Psychiatry
– volume: 168
  start-page: 418
  year: 2011
  end-page: 426
  ident: bib65
  article-title: Correlation of individual differences in schizotypal personality traits with amphetamine-induced dopamine release in striatal and extrastriatal brain regions
  publication-title: Am J Psychiatry
– volume: 63
  start-page: 1386
  year: 2006
  end-page: 1395
  ident: bib124
  article-title: Modeling sensitization to stimulants in humans: An [11C]raclopride/positron emission tomography study in healthy men
  publication-title: Arch Gen Psychiatry
– year: 2019
  ident: bib134
  article-title: Schizophrenia—an overview
  publication-title: JAMA Psychiatry
– volume: 71
  start-page: 898
  year: 2012
  end-page: 905
  ident: bib41
  article-title: Alterations of the brain reward system in antipsychotic nave schizophrenia patients
  publication-title: Biol Psychiatry
– volume: 27
  start-page: 821
  year: 2017
  end-page: 832
  ident: bib21
  article-title: Midbrain dopamine neurons signal belief in choice accuracy during a perceptual decision
  publication-title: Curr Biol
– volume: 67
  start-page: 1246
  year: 2010
  ident: bib31
  article-title: Midbrain activation during pavlovian conditioning and delusional symptoms in schizophrenia
  publication-title: Arch Gen Psychiatry
– year: 2019
  ident: bib24
  article-title: Ramping and state uncertainty in the dopamine signal
  publication-title: bioRxiv
– volume: 1
  start-page: 148
  year: 2014
  end-page: 158
  ident: bib89
  article-title: Computational psychiatry: The brain as a phantastic organ
  publication-title: Lancet Psychiatry
– volume: 14
  start-page: 184
  year: 2015
  end-page: 185
  ident: bib91
  article-title: Phenomenology is Bayesian in its application to delusions
  publication-title: World Psychiatry
– volume: 4
  start-page: 215
  year: 2010
  ident: bib93
  article-title: Attention, uncertainty, and free-energy
  publication-title: Front Hum Neurosci
– volume: 24
  start-page: 1502
  year: 2019
  end-page: 1512
  ident: bib67
  article-title: Determinants of treatment response in first-episode psychosis: An 18 F-DOPA PET study
  publication-title: Mol Psychiatry
– year: 2019
  ident: bib78
  article-title: Evidence of reward system dysfunction in youth at clinical high-risk for psychosis from two event-related fMRI paradigms
  publication-title: Schizophr Res
– volume: 42
  start-page: 205
  year: 2019
  end-page: 220
  ident: bib56
  article-title: Schizophrenia, dopamine and the striatum: From biology to symptoms
  publication-title: Trends Neurosci
– year: 2019
  ident: bib25
  article-title: Ramping and phasic dopamine activity accounts for efficient cognitive resource allocation during reinforcement learning
  publication-title: bioRxiv
– volume: 81
  start-page: 52
  year: 2016
  end-page: 66
  ident: bib69
  article-title: An integrative perspective on the role of dopamine in schizophrenia
  publication-title: Biol Psychiatry
– volume: 9
  start-page: 1
  year: 2019
  end-page: 22
  ident: bib95
  article-title: Introducing a Bayesian model of selective attention based on active inference
  publication-title: Sci Rep
– volume: 23
  start-page: 126
  year: 2012
  end-page: 132
  ident: bib60
  article-title: Striatal dopamine D2/3 receptor binding following dopamine depletion in subjects at ultra high risk for psychosis
  publication-title: Eur Neuropsychopharmacol
– volume: 7
  start-page: e1245
  year: 2017
  ident: bib77
  article-title: Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis [published correction appears in Transl Psychiatry 2018; 8:170]
  publication-title: Transl Psychiatry
– volume: 17
  start-page: 183
  year: 2016
  end-page: 195
  ident: bib14
  article-title: Dopamine reward prediction-error signalling: A two-component response
  publication-title: Nat Rev Neurosci
– volume: 66
  start-page: 13
  year: 2009
  end-page: 20
  ident: bib57
  article-title: Elevated striatal dopamine function linked to prodromal signs of schizophrenia
  publication-title: Arch Gen Psychiatry
– volume: 30
  start-page: 1145
  year: 2016
  end-page: 1155
  ident: bib70
  article-title: Prediction error, ketamine and psychosis: An updated model
  publication-title: J Psychopharmacol
– volume: 31
  start-page: 795
  year: 2005
  end-page: 799
  ident: bib111
  article-title: Schizophrenia and urbanicity: A major environmental influence—conditional on genetic risk
  publication-title: Schizophr Bull
– volume: 9
  start-page: 107704
  year: 2019
  ident: bib144
  article-title: Antipsychotics: Mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology
  publication-title: Neuropharmacology
– volume: 66
  start-page: 50
  year: 2012
  end-page: 56
  ident: bib75
  article-title: Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia
  publication-title: Neuropsychobiology
– volume: 32
  start-page: 9582
  year: 2012
  end-page: 9587
  ident: bib137
  article-title: Dopamine supports coupling of attention-related networks
  publication-title: J Neurosci
– volume: 68
  start-page: 815
  year: 2010
  end-page: 834
  ident: bib11
  article-title: Dopamine in motivational control: Rewarding, aversive, and alerting
  publication-title: Neuron
– volume: 29
  start-page: 3311
  year: 2017
  end-page: 3326
  ident: bib26
  article-title: Dopamine, inference, and uncertainty
  publication-title: Neural Comput
– volume: 81
  start-page: 9
  year: 2017
  end-page: 20
  ident: bib107
  article-title: The role of genes, stress, and dopamine in the development of schizophrenia
  publication-title: Biol Psychiatry
– volume: 23
  start-page: 114
  year: 2019
  end-page: 127
  ident: bib94
  article-title: Hallucinations and strong priors
  publication-title: Trends Cogn Sci
– volume: 44
  start-page: 147
  year: 2018
  end-page: 157
  ident: bib84
  article-title: Ventral striatal dysfunction and symptom expression in individuals with schizotypal personality traits and early psychosis
  publication-title: Schizophr Bull
– volume: 4
  start-page: 1
  year: 2011
  end-page: 14
  ident: bib38
  article-title: Aberrant effective connectivity in schizophrenia patients during appetitive conditioning
  publication-title: Front Hum Neurosci
– volume: 73
  start-page: 852
  year: 2016
  end-page: 861
  ident: bib85
  article-title: Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents
  publication-title: JAMA Psychiatry
– volume: 22
  start-page: 32
  year: 1998
  ident: bib12
  article-title: Real-time assessments of dopamine function during behavior: Single-unit recording, iontophoresis, and fast-scan cyclic voltammetry in awake, unrestrained rats
  publication-title: Alcohol Clin Exp Res
– volume: 363
  start-page: 3801
  year: 2008
  end-page: 3811
  ident: bib22
  article-title: Review. Explicit neural signals reflecting reward uncertainty
  publication-title: Philos Trans R Soc Lond B Biol Sci
– volume: 10
  start-page: 502
  year: 2016
  ident: bib90
  article-title: Thought insertion as a self-disturbance: An integration of predictive coding and phenomenological approaches
  publication-title: Front Hum Neurosci
– volume: 42
  start-page: 712
  year: 2016
  end-page: 722
  ident: bib114
  article-title: Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: An experience sampling study
  publication-title: Schizophr Bull
– volume: 4
  start-page: 1
  year: 2013
  end-page: 26
  ident: bib28
  article-title: The computational anatomy of psychosis
  publication-title: Front Psychiatry
– volume: 201
  start-page: 218
  year: 2012
  end-page: 221
  ident: bib64
  article-title: Schizotypy trait and striatal dopamine receptors in healthy volunteers
  publication-title: Psychiatry Res Neuroimaging
– volume: 72
  start-page: 1243
  year: 2015
  end-page: 1251
  ident: bib74
  article-title: Ventral striatal activation during reward processing in psychosis: A neurofunctional meta-analysis
  publication-title: JAMA Psychiatry
– volume: 158
  start-page: 25
  year: 2014
  end-page: 31
  ident: bib115
  article-title: Blunted cortisol awakening response in people at ultra high risk of developing psychosis
  publication-title: Schizophr Res
– volume: 67
  start-page: 145
  year: 1992
  end-page: 163
  ident: bib5
  article-title: Responses of monkey dopamine neurons during learning of behavioral reactions
  publication-title: J Neurophysiol
– volume: 35
  start-page: 2427
  year: 2010
  end-page: 2439
  ident: bib37
  article-title: Abnormal responses to monetary outcomes in cortex, but not in the basal ganglia, in schizophrenia
  publication-title: Neuropsychopharmacology
– volume: 34
  start-page: 1567
  year: 2009
  end-page: 1577
  ident: bib34
  article-title: Patients with schizophrenia have a reduced neural response to both unpredictable and predictable primary reinforcers
  publication-title: Neuropsychopharmacology
– volume: 28
  start-page: 11673
  year: 2008
  end-page: 11684
  ident: bib8
  article-title: Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials
  publication-title: J Neurosci
– volume: 106
  start-page: 4894
  year: 2009
  end-page: 4899
  ident: bib10
  article-title: Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli
  publication-title: Proc Natl Acad Sci U S A
– volume: 39
  start-page: 1087
  year: 2013
  end-page: 1095
  ident: bib99
  article-title: When Broca goes uninformed: Reduced information flow to Broca’s area in schizophrenia patients with auditory hallucinations
  publication-title: Schizophr Bull
– volume: 115
  start-page: E10167
  year: 2018
  end-page: E10176
  ident: bib15
  article-title: Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia
  publication-title: Proc Natl Acad Sci U S A
– volume: 176
  start-page: 171
  year: 2016
  end-page: 176
  ident: bib122
  article-title: Adversity in childhood linked to elevated striatal dopamine function in adulthood
  publication-title: Schizophr Res
– volume: 29
  start-page: 207
  year: 2011
  end-page: 213
  ident: bib136
  article-title: Developmental pathology, dopamine, stress and schizophrenia
  publication-title: Int J Dev Neurosci
– volume: 43
  start-page: 293
  year: 2017
  end-page: 301
  ident: bib121
  article-title: Elevated striatal dopamine function in immigrants and their children: A risk mechanism for psychosis
  publication-title: Schizophr Bull
– volume: 65
  start-page: 1032
  year: 2009
  end-page: 1039
  ident: bib33
  article-title: Reward feedback alterations in unmedicated schizophrenia patients: Relevance for delusions
  publication-title: Biol Psychiatry
– volume: 1
  start-page: 1
  year: 2017
  end-page: 18
  ident: bib19
  article-title: Dopaminergic medication increases reliance on current information in Parkinson’s disease
  publication-title: Nat Hum Behav
– volume: 39
  start-page: 1479
  year: 2014
  end-page: 1489
  ident: bib66
  article-title: Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use
  publication-title: Neuropsychopharmacology
– volume: 17
  start-page: 196
  year: 2018
  end-page: 209
  ident: bib142
  article-title: Lack of evidence to favor specific preventive interventions in psychosis: A network meta-analysis
  publication-title: World Psychiatry
– volume: 45
  start-page: 670
  year: 2018
  end-page: 679
  ident: bib133
  article-title: Impaired prefrontal cortical dopamine release in schizophrenia during a cognitive task: A [11C]FLB 457 positron emission tomography study
  publication-title: Schizophr Bull
– volume: 13
  start-page: 572
  year: 2012
  end-page: 586
  ident: bib16
  article-title: Knowing how much you don’t know: A neural organization of uncertainty estimates
  publication-title: Nat Rev Neurosci
– volume: 275
  start-page: 1593
  year: 1997
  end-page: 1599
  ident: bib2
  article-title: A neural substrate of prediction and reward
  publication-title: Adv Sci
– volume: 91
  start-page: 11651
  year: 1994
  end-page: 11654
  ident: bib53
  article-title: Elevated dopa decarboxylase activity in living brain of patients with psychosis
  publication-title: Proc Natl Acad Sci U S A
– volume: 32
  start-page: 321
  year: 2009
  end-page: 328
  ident: bib43
  article-title: Functional imaging of the human dopaminergic midbrain
  publication-title: Trends Neurosci
– volume: 97
  start-page: 8104
  year: 2000
  end-page: 8109
  ident: bib51
  article-title: Increased baseline occupancy of D2 receptors by dopamine in schizophrenia
  publication-title: Proc Natl Acad Sci U S A
– volume: 136
  start-page: 3242
  year: 2013
  end-page: 3251
  ident: bib48
  article-title: Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study
  publication-title: Brain
– volume: 22
  start-page: 918
  year: 2010
  end-page: 930
  ident: bib126
  article-title: Salience representation in the parietal and frontal cortex
  publication-title: J Cogn Neurosci
– volume: 34
  start-page: 8072
  year: 2014
  end-page: 8082
  ident: bib100
  article-title: Deficits in predictive coding underlie hallucinations in schizophrenia
  publication-title: J Neurosci
– volume: 36
  start-page: 472
  year: 2010
  end-page: 485
  ident: bib101
  article-title: Dopaminergic dysfunction in schizophrenia: Salience attribution revisited
  publication-title: Schizophr Bull
– volume: 74
  start-page: 1206
  year: 2017
  end-page: 1213
  ident: bib54
  article-title: A test of the transdiagnostic dopamine hypothesis of psychosis using positron emission tomographic imaging in bipolar affective disorder and schizophrenia
  publication-title: JAMA Psychiatry
– volume: 41
  start-page: 494
  year: 2015
  end-page: 502
  ident: bib109
  article-title: Does population density and neighborhood deprivation predict schizophrenia? A nationwide Swedish family-based study of 2.4 million individuals
  publication-title: Schizophr Bull
– volume: 47
  start-page: 243
  year: 2017
  end-page: 254
  ident: bib80
  article-title: Longitudinal alterations in motivational salience processing in ultra-high-risk subjects for psychosis
  publication-title: Psychol Med
– volume: 21
  start-page: 238
  year: 2007
  end-page: 252
  ident: bib127
  article-title: From prediction error to psychosis: Ketamine as a pharmacological model of delusions
  publication-title: J Psychopharmacol
– volume: 74
  start-page: 410
  year: 2013
  end-page: 417
  ident: bib117
  article-title: Cortisol levels and risk for psychosis: Initial findings from the North American Prodrome Longitudinal Study
  publication-title: Biol Psychiatry
– volume: 67
  start-page: 231
  year: 2010
  ident: bib50
  article-title: Increased synaptic dopamine function in associative regions of the striatum in schizophrenia
  publication-title: Arch Gen Psychiatry
– volume: 74
  start-page: 467
  year: 2013
  end-page: 474
  ident: bib138
  article-title: Disruption of anterior insula modulation of large-scale brain networks in schizophrenia
  publication-title: Biol Psychiatry
– volume: 55
  start-page: 1001
  year: 2004
  end-page: 1006
  ident: bib52
  article-title: Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide
  publication-title: Biol Psychiatry
– volume: 69
  start-page: 776
  year: 2012
  end-page: 786
  ident: bib44
  article-title: The nature of dopamine dysfunction in schizophrenia and what this means for treatment
  publication-title: Arch Gen Psychiatry
– volume: 67
  start-page: 683
  year: 2010
  end-page: 691
  ident: bib62
  article-title: Abnormal frontostriatal interactions in people with prodromal signs of psychosis: A multimodal imaging study
  publication-title: Arch Gen Psychiatry
– volume: 13
  start-page: 293
  year: 2009
  end-page: 301
  ident: bib87
  article-title: The free-energy principle: a rough guide to the brain?
  publication-title: Trends Cogn Sci
– volume: 442
  start-page: 1042
  year: 2006
  end-page: 1045
  ident: bib7
  article-title: Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans
  publication-title: Nature
– volume: 17
  start-page: 280
  year: 2012
  end-page: 289
  ident: bib40
  article-title: Disambiguating ventral striatum fMRI-related bold signal during reward prediction in schizophrenia
  publication-title: Mol Psychiatry
– volume: 46
  start-page: 670
  year: 2020
  end-page: 679
  ident: bib83
  article-title: Neural circuitry of novelty salience processing in psychosis risk: Association with clinical outcome
  publication-title: Schizophr Bull
– volume: 84
  start-page: 634
  year: 2018
  end-page: 643
  ident: bib86
  article-title: The predictive coding account of psychosis
  publication-title: Biol Psychiatry
– volume: 162
  start-page: 12
  year: 2005
  end-page: 24
  ident: bib110
  article-title: Schizophrenia and migration: A meta-analysis and review
  publication-title: Am J Psychiatry
– volume: 38
  start-page: 98
  year: 2013
  end-page: 106
  ident: bib61
  article-title: Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive tasks
  publication-title: J Psychiatry Neurosci
– volume: 44
  start-page: 1301
  year: 2018
  end-page: 1311
  ident: bib49
  article-title: Defining the locus of dopaminergic dysfunction in schizophrenia: A meta-analysis and test of the mesolimbic hypothesis
  publication-title: Schizophr Bull
– volume: 125
  start-page: 388
  year: 2012
  end-page: 399
  ident: bib108
  article-title: Adversity and psychosis: A 10-year prospective study investigating synergism between early and recent adversity in psychosis
  publication-title: Acta Psychiatr Scand
– volume: 38
  start-page: 661
  year: 2012
  end-page: 671
  ident: bib112
  article-title: Childhood adversities increase the risk of psychosis: A meta-analysis of patient-control, prospective-and cross-sectional cohort studies
  publication-title: Schizophr Bull
– volume: 108
  start-page: 19767
  year: 2011
  end-page: 19771
  ident: bib20
  article-title: Dopamine neurons code subjective sensory experience and uncertainty of perceptual decisions
  publication-title: Proc Natl Acad Sci U S A
– volume: 8
  start-page: 382
  year: 2014
  ident: bib76
  article-title: Symptom dimensions are associated with reward processing in unmedicated persons at risk for psychosis
  publication-title: Front Behav Neurosci
– volume: 211
  start-page: 104
  year: 2013
  end-page: 111
  ident: bib35
  article-title: Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia
  publication-title: Psychiatry Res Neuroimaging
– volume: 429
  start-page: 664
  year: 2004
  end-page: 667
  ident: bib3
  article-title: Temporal difference models describe higher-order learning in humans
  publication-title: Nature
– volume: 205
  start-page: 1
  year: 2014
  end-page: 3
  ident: bib113
  article-title: A neurobiological hypothesis for the classification of schizophrenia: Type A (hyperdopaminergic) and type B (normodopaminergic)
  publication-title: Br J Psychiatry
– volume: 13
  start-page: 267
  year: 2008
  end-page: 276
  ident: bib36
  article-title: Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
  publication-title: Mol Psychiatry
– volume: 14
  start-page: 1
  year: 2018
  end-page: 23
  ident: bib39
  article-title: Modeling subjective relevance in schizophrenia and its relation to aberrant salience
  publication-title: PLoS Comput Biol
– volume: 16
  start-page: 88
  year: 2001
  end-page: 94
  ident: bib106
  article-title: Schizophrenic delusions in Seoul, Shanghai and Taipei: A transcultural study
  publication-title: J Korean Med Sci
– volume: 190
  start-page: 133
  year: 2019
  end-page: 143
  ident: bib92
  article-title: Decision-making in schizophrenia: A predictive-coding perspective
  publication-title: Neuroimage
– volume: 39
  start-page: 1328
  year: 2013
  end-page: 1336
  ident: bib82
  article-title: Neural and behavioral correlates of aberrant salience in individuals at risk for psychosis
  publication-title: Schizophr Bull
– volume: 39
  start-page: 1180
  year: 2013
  end-page: 1186
  ident: bib104
  article-title: The social defeat hypothesis of schizophrenia: An update
  publication-title: Schizophr Bull
– volume: 7
  year: 2017
  ident: bib139
  article-title: Inflammation and the neural diathesis-stress hypothesis of schizophrenia: A reconceptualization
  publication-title: Transl Psychiatry
– volume: 90
  start-page: 1127
  year: 2016
  end-page: 1138
  ident: bib27
  article-title: Adaptive prediction error coding in the human midbrain and striatum facilitates behavioral adaptation and learning efficiency
  publication-title: Neuron
– volume: 5
  start-page: 816
  year: 2018
  end-page: 823
  ident: bib140
  article-title: The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: A cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study
  publication-title: Lancet Psychiatry
– volume: 29
  start-page: 671
  year: 2003
  end-page: 692
  ident: bib120
  article-title: The stress cascade and schizophrenia: Etiology and onset
  publication-title: Schizophr Bull
– volume: 71
  start-page: 561
  year: 2012
  end-page: 567
  ident: bib46
  article-title: Increased stress-induced dopamine release in psychosis
  publication-title: Biol Psychiatry
– volume: 383
  start-page: 1677
  year: 2014
  end-page: 1687
  ident: bib68
  article-title: Schizophrenia: An integrated sociodevelopmental-cognitive model
  publication-title: Lancet
– volume: 63
  start-page: 611
  year: 2006
  end-page: 621
  ident: bib128
  article-title: Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: Linking cognition, brain activity, and psychosis
  publication-title: Arch Gen Psychiatry
– volume: 28
  start-page: 503
  year: 2018
  end-page: 514
  ident: bib97
  article-title: A perceptual inference mechanism for hallucinations linked to striatal dopamine
  publication-title: Curr Biol
– volume: 16
  start-page: 67
  year: 2011
  end-page: 75
  ident: bib131
  article-title: Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
  publication-title: Mol Psychiatry
– volume: 187
  start-page: 222
  year: 2006
  end-page: 228
  ident: bib42
  article-title: Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
  publication-title: Psychopharmacology (Berl)
– volume: 369
  start-page: 20130481
  year: 2014
  ident: bib18
  article-title: The anatomy of choice: Dopamine and decision-making
  publication-title: Philos Trans R Soc B Biol Sci
– volume: 130
  start-page: 2387
  year: 2007
  end-page: 2400
  ident: bib29
  article-title: Disrupted prediction-error signal in psychosis: Evidence for an associative account of delusions
  publication-title: Brain
– volume: 65
  start-page: 1091
  year: 2009
  end-page: 1093
  ident: bib47
  article-title: Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects
  publication-title: Biol Psychiatry
– volume: 50
  start-page: 3612
  year: 2012
  end-page: 3620
  ident: bib103
  article-title: The neurobiology of schizotypy: Fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people
  publication-title: Neuropsychologia
– volume: 29
  start-page: 1023
  year: 2019
  end-page: 1032
  ident: bib135
  article-title: Prefrontal cortical dopamine release in clinical high risk for psychosis during a cognitive task: A [11C]FLB457 positron emission tomography study
  publication-title: Eur Neuropsychopharmacol
– volume: 168
  start-page: 1311
  year: 2011
  end-page: 1317
  ident: bib63
  article-title: Dopamine synthesis capacity before onset of psychosis: A prospective [18F]-DOPA PET imaging study
  publication-title: Am J Psychiatry
– volume: 33
  start-page: 13701
  year: 2013
  end-page: 13712
  ident: bib129
  article-title: Delusions and the role of beliefs in perceptual inference
  publication-title: J Neurosci
– volume: 96
  start-page: 651
  year: 2000
  end-page: 656
  ident: bib13
  article-title: Mesocortical and mesostriatal dopamine responses to salient non-rewards events
  publication-title: Neuroscience
– volume: 99
  start-page: 169
  year: 1999
  end-page: 179
  ident: bib6
  article-title: An electrophysiological characterization of ventral tegmental area dopaminergic neurons during differential pavlovian fear conditioning in the awake rabbit
  publication-title: Behav Brain Res
– volume: 9
  start-page: 521
  year: 2015
  ident: bib102
  article-title: Linking unfounded beliefs to genetic dopamine availability
  publication-title: Front Hum Neurosci
– volume: 17
  start-page: 9
  year: 2002
  end-page: 16
  ident: bib72
  article-title: Dopaminergic dysfunction in alcoholism and schizophrenia—psychopathological and behavioral correlates
  publication-title: Eur Psychiatry
– volume: 149
  start-page: 56
  year: 2013
  end-page: 62
  ident: bib143
  article-title: Preventing a first episode of psychosis: Meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-ups
  publication-title: Schizophr Res
– volume: 46
  start-page: 670
  year: 2020
  ident: 10.1016/j.biopsych.2020.03.012_bib83
  article-title: Neural circuitry of novelty salience processing in psychosis risk: Association with clinical outcome
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbz089
– volume: 383
  start-page: 1677
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib68
  article-title: Schizophrenia: An integrated sociodevelopmental-cognitive model
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)62036-X
– volume: 44
  start-page: 147
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib84
  article-title: Ventral striatal dysfunction and symptom expression in individuals with schizotypal personality traits and early psychosis
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sby015.204
– volume: 158
  start-page: 25
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib115
  article-title: Blunted cortisol awakening response in people at ultra high risk of developing psychosis
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2014.06.041
– volume: 81
  start-page: 9
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib107
  article-title: The role of genes, stress, and dopamine in the development of schizophrenia
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2016.07.014
– volume: 34
  start-page: 8072
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib100
  article-title: Deficits in predictive coding underlie hallucinations in schizophrenia
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.0200-14.2014
– volume: 42
  start-page: 205
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib56
  article-title: Schizophrenia, dopamine and the striatum: From biology to symptoms
  publication-title: Trends Neurosci
  doi: 10.1016/j.tins.2018.12.004
– volume: 4
  start-page: 1
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib28
  article-title: The computational anatomy of psychosis
  publication-title: Front Psychiatry
  doi: 10.3389/fpsyt.2013.00047
– volume: 106
  start-page: 4894
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib10
  article-title: Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.0811507106
– volume: 149
  start-page: 56
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib143
  article-title: Preventing a first episode of psychosis: Meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-ups
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2013.07.004
– volume: 125
  start-page: 388
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib108
  article-title: Adversity and psychosis: A 10-year prospective study investigating synergism between early and recent adversity in psychosis
  publication-title: Acta Psychiatr Scand
  doi: 10.1111/j.1600-0447.2011.01805.x
– volume: 74
  start-page: 106
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib59
  article-title: Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2012.11.017
– volume: 23
  start-page: 126
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib60
  article-title: Striatal dopamine D2/3 receptor binding following dopamine depletion in subjects at ultra high risk for psychosis
  publication-title: Eur Neuropsychopharmacol
  doi: 10.1016/j.euroneuro.2012.04.015
– volume: 72
  start-page: 316
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib132
  article-title: Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2014.2414
– volume: 29
  start-page: 409
  year: 2006
  ident: 10.1016/j.biopsych.2020.03.012_bib32
  article-title: Dysfunction of ventral striatal reward prediction in schizophrenia
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2005.07.051
– volume: 30
  start-page: 194
  year: 2007
  ident: 10.1016/j.biopsych.2020.03.012_bib55
  article-title: Dopamine neuron systems in the brain: An update
  publication-title: Trends Neurosci
  doi: 10.1016/j.tins.2007.03.006
– volume: 299
  start-page: 1898
  year: 2003
  ident: 10.1016/j.biopsych.2020.03.012_bib145
  article-title: Discrete coding of reward probability and uncertainty by dopamine neurons
  publication-title: Science
  doi: 10.1126/science.1077349
– volume: 44
  start-page: 542
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib45
  article-title: Nigral stress-induced dopamine release in clinical high risk and antipsychotic-naïve schizophrenia
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbx042
– volume: 206
  start-page: 515
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib88
  article-title: From drugs to deprivation: A Bayesian framework for understanding models of psychosis
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-009-1561-0
– volume: 21
  start-page: 238
  year: 2007
  ident: 10.1016/j.biopsych.2020.03.012_bib127
  article-title: From prediction error to psychosis: Ketamine as a pharmacological model of delusions
  publication-title: J Psychopharmacol
  doi: 10.1177/0269881107077716
– volume: 68
  start-page: 815
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib11
  article-title: Dopamine in motivational control: Rewarding, aversive, and alerting
  publication-title: Neuron
  doi: 10.1016/j.neuron.2010.11.022
– volume: 50
  start-page: 3612
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib103
  article-title: The neurobiology of schizotypy: Fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people
  publication-title: Neuropsychologia
  doi: 10.1016/j.neuropsychologia.2012.09.045
– volume: 66
  start-page: 50
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib75
  article-title: Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia
  publication-title: Neuropsychobiology
  doi: 10.1159/000337130
– volume: 39
  start-page: 1328
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib82
  article-title: Neural and behavioral correlates of aberrant salience in individuals at risk for psychosis
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbs147
– volume: 35
  start-page: 2427
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib37
  article-title: Abnormal responses to monetary outcomes in cortex, but not in the basal ganglia, in schizophrenia
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2010.126
– volume: 36
  start-page: 472
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib101
  article-title: Dopaminergic dysfunction in schizophrenia: Salience attribution revisited
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbq031
– volume: 84
  start-page: 634
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib86
  article-title: The predictive coding account of psychosis
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2018.05.015
– volume: 16
  start-page: 67
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib131
  article-title: Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
  publication-title: Mol Psychiatry
  doi: 10.1038/mp.2009.108
– volume: 72
  start-page: 1243
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib74
  article-title: Ventral striatal activation during reward processing in psychosis: A neurofunctional meta-analysis
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2015.2196
– volume: 47
  start-page: 243
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib80
  article-title: Longitudinal alterations in motivational salience processing in ultra-high-risk subjects for psychosis
  publication-title: Psychol Med
  doi: 10.1017/S0033291716002439
– volume: 115
  start-page: E10167
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib15
  article-title: Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1809298115
– volume: 35
  start-page: 549
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib105
  article-title: The dopamine hypothesis of schizophrenia: Version III—the final common pathway
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbp006
– volume: 27
  start-page: 821
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib21
  article-title: Midbrain dopamine neurons signal belief in choice accuracy during a perceptual decision
  publication-title: Curr Biol
  doi: 10.1016/j.cub.2017.02.026
– volume: 16
  start-page: 885
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib58
  article-title: Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: A PET study
  publication-title: Mol Psychiatry
  doi: 10.1038/mp.2011.20
– volume: 130
  start-page: 2387
  year: 2007
  ident: 10.1016/j.biopsych.2020.03.012_bib29
  article-title: Disrupted prediction-error signal in psychosis: Evidence for an associative account of delusions
  publication-title: Brain
  doi: 10.1093/brain/awm173
– volume: 74
  start-page: 1206
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib54
  article-title: A test of the transdiagnostic dopamine hypothesis of psychosis using positron emission tomographic imaging in bipolar affective disorder and schizophrenia
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2017.2943
– volume: 201
  start-page: 218
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib64
  article-title: Schizotypy trait and striatal dopamine receptors in healthy volunteers
  publication-title: Psychiatry Res Neuroimaging
  doi: 10.1016/j.pscychresns.2011.07.003
– volume: 211
  start-page: 104
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib35
  article-title: Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia
  publication-title: Psychiatry Res Neuroimaging
  doi: 10.1016/j.pscychresns.2012.06.003
– volume: 44
  start-page: 1301
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib49
  article-title: Defining the locus of dopaminergic dysfunction in schizophrenia: A meta-analysis and test of the mesolimbic hypothesis
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbx180
– volume: 162
  start-page: 12
  year: 2005
  ident: 10.1016/j.biopsych.2020.03.012_bib110
  article-title: Schizophrenia and migration: A meta-analysis and review
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.162.1.12
– volume: 22
  start-page: 918
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib126
  article-title: Salience representation in the parietal and frontal cortex
  publication-title: J Cogn Neurosci
  doi: 10.1162/jocn.2009.21233
– volume: 29
  start-page: 207
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib136
  article-title: Developmental pathology, dopamine, stress and schizophrenia
  publication-title: Int J Dev Neurosci
  doi: 10.1016/j.ijdevneu.2010.08.002
– volume: 74
  start-page: 410
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib117
  article-title: Cortisol levels and risk for psychosis: Initial findings from the North American Prodrome Longitudinal Study
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2013.02.016
– volume: 9
  start-page: 107704
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib144
  article-title: Antipsychotics: Mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology
  publication-title: Neuropharmacology
– volume: 11
  start-page: 1
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib23
  article-title: Tamping ramping: Algorithmic, implementational, and computational explanations of phasic dopamine signals in the accumbens
  publication-title: PLoS Comput Biol
  doi: 10.1371/journal.pcbi.1004622
– year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib134
  article-title: Schizophrenia—an overview
  publication-title: JAMA Psychiatry
– volume: 97
  start-page: 8104
  year: 2000
  ident: 10.1016/j.biopsych.2020.03.012_bib51
  article-title: Increased baseline occupancy of D2 receptors by dopamine in schizophrenia
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.97.14.8104
– volume: 108
  start-page: 19767
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib20
  article-title: Dopamine neurons code subjective sensory experience and uncertainty of perceptual decisions
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1117636108
– volume: 100
  start-page: 206
  year: 2008
  ident: 10.1016/j.biopsych.2020.03.012_bib119
  article-title: Effects of acute metabolic stress on the dopaminergic and pituitary–adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2007.11.009
– volume: 7
  start-page: e1245
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib77
  article-title: Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis [published correction appears in Transl Psychiatry 2018; 8:170]
  publication-title: Transl Psychiatry
  doi: 10.1038/tp.2017.174
– volume: 67
  start-page: 145
  year: 1992
  ident: 10.1016/j.biopsych.2020.03.012_bib5
  article-title: Responses of monkey dopamine neurons during learning of behavioral reactions
  publication-title: J Neurophysiol
  doi: 10.1152/jn.1992.67.1.145
– volume: 55
  start-page: 1001
  year: 2004
  ident: 10.1016/j.biopsych.2020.03.012_bib52
  article-title: Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2004.01.018
– volume: 24
  start-page: 1502
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib67
  article-title: Determinants of treatment response in first-episode psychosis: An 18 F-DOPA PET study
  publication-title: Mol Psychiatry
  doi: 10.1038/s41380-018-0042-4
– volume: 23
  start-page: 114
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib94
  article-title: Hallucinations and strong priors
  publication-title: Trends Cogn Sci
  doi: 10.1016/j.tics.2018.12.001
– volume: 14
  start-page: 1
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib39
  article-title: Modeling subjective relevance in schizophrenia and its relation to aberrant salience
  publication-title: PLoS Comput Biol
  doi: 10.1371/journal.pcbi.1006319
– volume: 65
  start-page: 1091
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib47
  article-title: Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2008.12.007
– volume: 67
  start-page: 683
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib62
  article-title: Abnormal frontostriatal interactions in people with prodromal signs of psychosis: A multimodal imaging study
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2010.77
– volume: 28
  start-page: 11673
  year: 2008
  ident: 10.1016/j.biopsych.2020.03.012_bib8
  article-title: Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.3839-08.2008
– volume: 22
  start-page: 32
  year: 1998
  ident: 10.1016/j.biopsych.2020.03.012_bib12
  article-title: Real-time assessments of dopamine function during behavior: Single-unit recording, iontophoresis, and fast-scan cyclic voltammetry in awake, unrestrained rats
  publication-title: Alcohol Clin Exp Res
– volume: 32
  start-page: 9582
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib137
  article-title: Dopamine supports coupling of attention-related networks
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.0909-12.2012
– volume: 275
  start-page: 1593
  year: 1997
  ident: 10.1016/j.biopsych.2020.03.012_bib2
  article-title: A neural substrate of prediction and reward
  publication-title: Adv Sci
– volume: 30
  start-page: 1832
  year: 2005
  ident: 10.1016/j.biopsych.2020.03.012_bib9
  article-title: Restraint increases dopaminergic burst firing in awake rats
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1300730
– volume: 369
  start-page: 20130481
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib18
  article-title: The anatomy of choice: Dopamine and decision-making
  publication-title: Philos Trans R Soc B Biol Sci
  doi: 10.1098/rstb.2013.0481
– volume: 160
  start-page: 13
  year: 2003
  ident: 10.1016/j.biopsych.2020.03.012_bib71
  article-title: Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.160.1.13
– volume: 41
  start-page: 494
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib109
  article-title: Does population density and neighborhood deprivation predict schizophrenia? A nationwide Swedish family-based study of 2.4 million individuals
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbu105
– year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib25
  article-title: Ramping and phasic dopamine activity accounts for efficient cognitive resource allocation during reinforcement learning
  publication-title: bioRxiv
– volume: 69
  start-page: 776
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib44
  article-title: The nature of dopamine dysfunction in schizophrenia and what this means for treatment
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2012.169
– volume: 29
  start-page: 671
  year: 2003
  ident: 10.1016/j.biopsych.2020.03.012_bib120
  article-title: The stress cascade and schizophrenia: Etiology and onset
  publication-title: Schizophr Bull
  doi: 10.1093/oxfordjournals.schbul.a007038
– volume: 29
  start-page: 3311
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib26
  article-title: Dopamine, inference, and uncertainty
  publication-title: Neural Comput
  doi: 10.1162/neco_a_01023
– volume: 72
  start-page: 1024
  year: 1994
  ident: 10.1016/j.biopsych.2020.03.012_bib4
  article-title: Importance of unpredictability for reward responses in primate dopamine neurons
  publication-title: J Neurophysiol
  doi: 10.1152/jn.1994.72.2.1024
– volume: 99
  start-page: 169
  year: 1999
  ident: 10.1016/j.biopsych.2020.03.012_bib6
  article-title: An electrophysiological characterization of ventral tegmental area dopaminergic neurons during differential pavlovian fear conditioning in the awake rabbit
  publication-title: Behav Brain Res
  doi: 10.1016/S0166-4328(98)00102-8
– volume: 42
  start-page: 712
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib114
  article-title: Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: An experience sampling study
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbv190
– volume: 91
  start-page: 11651
  year: 1994
  ident: 10.1016/j.biopsych.2020.03.012_bib53
  article-title: Elevated dopa decarboxylase activity in living brain of patients with psychosis
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.91.24.11651
– volume: 90
  start-page: 1127
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib27
  article-title: Adaptive prediction error coding in the human midbrain and striatum facilitates behavioral adaptation and learning efficiency
  publication-title: Neuron
  doi: 10.1016/j.neuron.2016.04.019
– volume: 96
  start-page: 651
  year: 2000
  ident: 10.1016/j.biopsych.2020.03.012_bib13
  article-title: Mesocortical and mesostriatal dopamine responses to salient non-rewards events
  publication-title: Neuroscience
  doi: 10.1016/S0306-4522(00)00019-1
– volume: 13
  start-page: 267
  year: 2008
  ident: 10.1016/j.biopsych.2020.03.012_bib36
  article-title: Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
  publication-title: Mol Psychiatry
  doi: 10.1038/sj.mp.4002058
– volume: 13
  start-page: 572
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib16
  article-title: Knowing how much you don’t know: A neural organization of uncertainty estimates
  publication-title: Nat Rev Neurosci
  doi: 10.1038/nrn3289
– volume: 5
  start-page: 816
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib140
  article-title: The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: A cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study
  publication-title: Lancet Psychiatry
  doi: 10.1016/S2215-0366(18)30268-2
– year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib24
  article-title: Ramping and state uncertainty in the dopamine signal
  publication-title: bioRxiv
– volume: 65
  start-page: 1032
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib33
  article-title: Reward feedback alterations in unmedicated schizophrenia patients: Relevance for delusions
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2008.12.016
– volume: 13
  start-page: 293
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib87
  article-title: The free-energy principle: a rough guide to the brain?
  publication-title: Trends Cogn Sci
  doi: 10.1016/j.tics.2009.04.005
– volume: 187
  start-page: 222
  year: 2006
  ident: 10.1016/j.biopsych.2020.03.012_bib42
  article-title: Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
  publication-title: Psychopharmacology (Berl)
  doi: 10.1007/s00213-006-0405-4
– volume: 9
  start-page: 1
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib17
  article-title: Dopamine, reward learning, and active inference
  publication-title: Front Comput Neurosci
  doi: 10.3389/fncom.2015.00136
– volume: 33
  start-page: 473
  year: 2008
  ident: 10.1016/j.biopsych.2020.03.012_bib30
  article-title: The formation of abnormal associations in schizophrenia: Neural and behavioral evidence
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1301437
– volume: 71
  start-page: 561
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib46
  article-title: Increased stress-induced dopamine release in psychosis
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2011.10.009
– volume: 39
  start-page: 1087
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib99
  article-title: When Broca goes uninformed: Reduced information flow to Broca’s area in schizophrenia patients with auditory hallucinations
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbs107
– volume: 52
  start-page: 1655
  year: 1989
  ident: 10.1016/j.biopsych.2020.03.012_bib123
  article-title: Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens, and medial frontal cortex
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.1989.tb09224.x
– volume: 63
  start-page: 611
  year: 2006
  ident: 10.1016/j.biopsych.2020.03.012_bib128
  article-title: Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: Linking cognition, brain activity, and psychosis
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archpsyc.63.6.611
– volume: 28
  start-page: 309
  year: 1998
  ident: 10.1016/j.biopsych.2020.03.012_bib73
  article-title: What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
  publication-title: Brain Res Rev
  doi: 10.1016/S0165-0173(98)00019-8
– volume: 4
  start-page: 1
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib38
  article-title: Aberrant effective connectivity in schizophrenia patients during appetitive conditioning
  publication-title: Front Hum Neurosci
  doi: 10.3389/fnhum.2010.00239
– volume: 190
  start-page: 133
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib92
  article-title: Decision-making in schizophrenia: A predictive-coding perspective
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2018.05.074
– volume: 363
  start-page: 3801
  year: 2008
  ident: 10.1016/j.biopsych.2020.03.012_bib22
  article-title: Review. Explicit neural signals reflecting reward uncertainty
  publication-title: Philos Trans R Soc Lond B Biol Sci
  doi: 10.1098/rstb.2008.0152
– volume: 17
  start-page: 196
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib142
  article-title: Lack of evidence to favor specific preventive interventions in psychosis: A network meta-analysis
  publication-title: World Psychiatry
  doi: 10.1002/wps.20526
– volume: 39
  start-page: 1180
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib104
  article-title: The social defeat hypothesis of schizophrenia: An update
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbt134
– volume: 43
  start-page: 293
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib121
  article-title: Elevated striatal dopamine function in immigrants and their children: A risk mechanism for psychosis
  publication-title: Schizophr Bull
– volume: 429
  start-page: 664
  year: 2004
  ident: 10.1016/j.biopsych.2020.03.012_bib3
  article-title: Temporal difference models describe higher-order learning in humans
  publication-title: Nature
  doi: 10.1038/nature02581
– volume: 17
  start-page: 183
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib14
  article-title: Dopamine reward prediction-error signalling: A two-component response
  publication-title: Nat Rev Neurosci
  doi: 10.1038/nrn.2015.26
– volume: 32
  start-page: 321
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib43
  article-title: Functional imaging of the human dopaminergic midbrain
  publication-title: Trends Neurosci
  doi: 10.1016/j.tins.2009.02.005
– volume: 31
  start-page: 795
  year: 2005
  ident: 10.1016/j.biopsych.2020.03.012_bib111
  article-title: Schizophrenia and urbanicity: A major environmental influence—conditional on genetic risk
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbi060
– volume: 176
  start-page: 171
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib122
  article-title: Adversity in childhood linked to elevated striatal dopamine function in adulthood
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2016.06.005
– volume: 81
  start-page: 52
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib69
  article-title: An integrative perspective on the role of dopamine in schizophrenia
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2016.05.021
– volume: 14
  start-page: 184
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib91
  article-title: Phenomenology is Bayesian in its application to delusions
  publication-title: World Psychiatry
  doi: 10.1002/wps.20213
– volume: 16
  start-page: 88
  year: 2001
  ident: 10.1016/j.biopsych.2020.03.012_bib106
  article-title: Schizophrenic delusions in Seoul, Shanghai and Taipei: A transcultural study
  publication-title: J Korean Med Sci
  doi: 10.3346/jkms.2001.16.1.88
– volume: 442
  start-page: 1042
  year: 2006
  ident: 10.1016/j.biopsych.2020.03.012_bib7
  article-title: Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans
  publication-title: Nature
  doi: 10.1038/nature05051
– volume: 168
  start-page: 418
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib65
  article-title: Correlation of individual differences in schizotypal personality traits with amphetamine-induced dopamine release in striatal and extrastriatal brain regions
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2010.10020165
– volume: 74
  start-page: 467
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib138
  article-title: Disruption of anterior insula modulation of large-scale brain networks in schizophrenia
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2013.02.029
– volume: 67
  start-page: 231
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib50
  article-title: Increased synaptic dopamine function in associative regions of the striatum in schizophrenia
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2010.10
– volume: 43
  start-page: 1691
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib79
  article-title: Abnormal reward prediction-error signalling in antipsychotic naive individuals with first-episode psychosis or clinical risk for psychosis
  publication-title: Neuropsychopharmacology
  doi: 10.1038/s41386-018-0056-2
– volume: 10
  start-page: 502
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib90
  article-title: Thought insertion as a self-disturbance: An integration of predictive coding and phenomenological approaches
  publication-title: Front Hum Neurosci
  doi: 10.3389/fnhum.2016.00502
– volume: 45
  start-page: 670
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib133
  article-title: Impaired prefrontal cortical dopamine release in schizophrenia during a cognitive task: A [11C]FLB 457 positron emission tomography study
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sby076
– volume: 9
  start-page: 187
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib141
  article-title: Efficacy and acceptability of interventions for attenuated positive psychotic symptoms in individuals at clinical high risk of psychosis: A network meta-analysis
  publication-title: Front Psychiatry
  doi: 10.3389/fpsyt.2018.00187
– volume: 63
  start-page: 1386
  year: 2006
  ident: 10.1016/j.biopsych.2020.03.012_bib124
  article-title: Modeling sensitization to stimulants in humans: An [11C]raclopride/positron emission tomography study in healthy men
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archpsyc.63.12.1386
– volume: 9
  start-page: 1
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib95
  article-title: Introducing a Bayesian model of selective attention based on active inference
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-50138-8
– volume: 29
  start-page: 1023
  year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib135
  article-title: Prefrontal cortical dopamine release in clinical high risk for psychosis during a cognitive task: A [11C]FLB457 positron emission tomography study
  publication-title: Eur Neuropsychopharmacol
  doi: 10.1016/j.euroneuro.2019.06.004
– volume: 1
  start-page: 148
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib89
  article-title: Computational psychiatry: The brain as a phantastic organ
  publication-title: Lancet Psychiatry
  doi: 10.1016/S2215-0366(14)70275-5
– volume: 38
  start-page: 661
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib112
  article-title: Childhood adversities increase the risk of psychosis: A meta-analysis of patient-control, prospective-and cross-sectional cohort studies
  publication-title: Schizophr Bull
  doi: 10.1093/schbul/sbs050
– volume: 38
  start-page: 1767
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib130
  article-title: Enhanced predictive signalling in schizophrenia
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.23480
– volume: 30
  start-page: 1145
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib70
  article-title: Prediction error, ketamine and psychosis: An updated model
  publication-title: J Psychopharmacol
  doi: 10.1177/0269881116650087
– volume: 36
  start-page: 150
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib96
  article-title: Atypical scanpaths in schizophrenia: Evidence of a trait- or state-dependent phenomenon?
  publication-title: J Psychiatry Neurosci
  doi: 10.1503/jpn.090169
– volume: 73
  start-page: 852
  year: 2016
  ident: 10.1016/j.biopsych.2020.03.012_bib85
  article-title: Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2016.1135
– volume: 67
  start-page: 1246
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib31
  article-title: Midbrain activation during pavlovian conditioning and delusional symptoms in schizophrenia
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2010.169
– volume: 8
  start-page: 382
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib76
  article-title: Symptom dimensions are associated with reward processing in unmedicated persons at risk for psychosis
  publication-title: Front Behav Neurosci
  doi: 10.3389/fnbeh.2014.00382
– volume: 34
  start-page: 1567
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib34
  article-title: Patients with schizophrenia have a reduced neural response to both unpredictable and predictable primary reinforcers
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2008.214
– volume: 17
  start-page: 9
  year: 2002
  ident: 10.1016/j.biopsych.2020.03.012_bib72
  article-title: Dopaminergic dysfunction in alcoholism and schizophrenia—psychopathological and behavioral correlates
  publication-title: Eur Psychiatry
  doi: 10.1016/S0924-9338(02)00628-4
– volume: 205
  start-page: 1
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib113
  article-title: A neurobiological hypothesis for the classification of schizophrenia: Type A (hyperdopaminergic) and type B (normodopaminergic)
  publication-title: Br J Psychiatry
  doi: 10.1192/bjp.bp.113.138578
– volume: 136
  start-page: 3242
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib48
  article-title: Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study
  publication-title: Brain
  doi: 10.1093/brain/awt264
– volume: 17
  start-page: 280
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib40
  article-title: Disambiguating ventral striatum fMRI-related bold signal during reward prediction in schizophrenia
  publication-title: Mol Psychiatry
  doi: 10.1038/mp.2011.75
– volume: 46
  start-page: 1
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib116
  article-title: Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
  publication-title: Psychoneuroendocrinology
  doi: 10.1016/j.psyneuen.2014.03.010
– volume: 357
  start-page: 596
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib98
  article-title: Pavlovian conditioning–induced hallucinations result from overweighting of perceptual priors
  publication-title: Science
  doi: 10.1126/science.aan3458
– volume: 4
  start-page: 215
  year: 2010
  ident: 10.1016/j.biopsych.2020.03.012_bib93
  article-title: Attention, uncertainty, and free-energy
  publication-title: Front Hum Neurosci
  doi: 10.3389/fnhum.2010.00215
– volume: 66
  start-page: 13
  year: 2009
  ident: 10.1016/j.biopsych.2020.03.012_bib57
  article-title: Elevated striatal dopamine function linked to prodromal signs of schizophrenia
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2008.514
– volume: 39
  start-page: 1479
  year: 2014
  ident: 10.1016/j.biopsych.2020.03.012_bib66
  article-title: Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use
  publication-title: Neuropsychopharmacology
  doi: 10.1038/npp.2013.347
– volume: 33
  start-page: 13701
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib129
  article-title: Delusions and the role of beliefs in perceptual inference
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.1778-13.2013
– volume: 7
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib139
  article-title: Inflammation and the neural diathesis-stress hypothesis of schizophrenia: A reconceptualization
  publication-title: Transl Psychiatry
  doi: 10.1038/tp.2016.278
– volume: 38
  start-page: 98
  year: 2013
  ident: 10.1016/j.biopsych.2020.03.012_bib61
  article-title: Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive tasks
  publication-title: J Psychiatry Neurosci
  doi: 10.1503/jpn.110181
– volume: 1
  start-page: 1
  year: 2017
  ident: 10.1016/j.biopsych.2020.03.012_bib19
  article-title: Dopaminergic medication increases reliance on current information in Parkinson’s disease
  publication-title: Nat Hum Behav
  doi: 10.1038/s41562-017-0129
– ident: 10.1016/j.biopsych.2020.03.012_bib125
– volume: 32
  start-page: 2310
  year: 2007
  ident: 10.1016/j.biopsych.2020.03.012_bib118
  article-title: Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1301373
– volume: 168
  start-page: 1311
  year: 2011
  ident: 10.1016/j.biopsych.2020.03.012_bib63
  article-title: Dopamine synthesis capacity before onset of psychosis: A prospective [18F]-DOPA PET imaging study
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2011.11010160
– year: 2019
  ident: 10.1016/j.biopsych.2020.03.012_bib78
  article-title: Evidence of reward system dysfunction in youth at clinical high-risk for psychosis from two event-related fMRI paradigms
  publication-title: Schizophr Res
– volume: 28
  start-page: 503
  year: 2018
  ident: 10.1016/j.biopsych.2020.03.012_bib97
  article-title: A perceptual inference mechanism for hallucinations linked to striatal dopamine
  publication-title: Curr Biol
  doi: 10.1016/j.cub.2017.12.059
– volume: 166
  start-page: 17
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib81
  article-title: Modulation of motivational salience processing during the early stages of psychosis
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2015.04.036
– volume: 71
  start-page: 898
  year: 2012
  ident: 10.1016/j.biopsych.2020.03.012_bib41
  article-title: Alterations of the brain reward system in antipsychotic nave schizophrenia patients
  publication-title: Biol Psychiatry
  doi: 10.1016/j.biopsych.2012.02.007
– volume: 20
  start-page: 2369
  year: 2000
  ident: 10.1016/j.biopsych.2020.03.012_bib1
  article-title: Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.20-06-02369.2000
– volume: 9
  start-page: 521
  year: 2015
  ident: 10.1016/j.biopsych.2020.03.012_bib102
  article-title: Linking unfounded beliefs to genetic dopamine availability
  publication-title: Front Hum Neurosci
  doi: 10.3389/fnhum.2015.00521
SSID ssj0007221
Score 2.5724041
SecondaryResourceType review_article
Snippet The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis....
AbstractThe aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to...
SourceID proquest
pubmed
crossref
elsevier
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 304
SubjectTerms Bayes Theorem
Cognition
Computational psychiatry
Dopamine
Humans
Imaging
Prodrome
Psychiatric/Mental Health
Psychosis
Psychotic Disorders
Reward
Risk
Schizophrenia
Title Aberrant Salience, Information Processing, and Dopaminergic Signaling in People at Clinical High Risk for Psychosis
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0006322320313834
https://www.clinicalkey.es/playcontent/1-s2.0-S0006322320313834
https://dx.doi.org/10.1016/j.biopsych.2020.03.012
https://www.ncbi.nlm.nih.gov/pubmed/32430200
https://www.proquest.com/docview/2405305686
Volume 88
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NT9swFH-CIsYuCLrBypc8iSOhtvPlHKsCKpvgAEziZtmug8JYikg47LK_nefEqZgmNATHVn1O6_fy-_3cvA-AfTf7RoeZCUyoeICAFwXa5DpAcuI5FzYW3NU7n50nkx_Rt-v4egHGXS2MS6v02N9ieoPW_p2h383hfVG4Gl-kV2Q37toPijBahCWObC96sDQ6_T45nwNyyrkfnJcEzuBZofDtoS5mTV4xHhU5bfqdMv4SR72kQRsuOlmDVS8iyaj9nuuwYMs-LLdjJX_3YWXcTXHrw4cz__D8E1QjbR-QmmpyieLb_dID4quRnHeIrxlALjsgqpySIzxP_2pqAwtDLosbJ9nLG1LgJ5u0c6Jq4tuK3hGXL0IuiuonwQVJC6tVUX2Gq5Pjq_Ek8DMXAhNHUY2QbFBuK5anIbORyCyCENUisSxNlLK5tYYmNMs1CpPcpKlOM4uWWiiqGNXhBvTKWWm_AEHpZFB-5FlIdWQ51wguuCpNp4aLnE0HEHebLI3vR-7GYtzJLvHsVnbOkc45koYSnTOA4dzuvu3I8V-LtPOh7OpNESElksbbLG3lb_RKMllxSeU_wTiAbG75Vzy_6qpfu0CTGC3uCY4q7eyxkii_YnfmE8kANtsInO8BKuMQ16Bb77jyNnx0r9x_5izegV798Gh3UXTVeg8WD_-wPX9rPQHKRSrO
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9wwEB5RqhYuVVlK2T6oK3EkrOO8j2hbtAWWQ1kkbpbtdVahkEUkHLjw25lJnKWoQkXtNck4iWfyzed4HgDb1PtGB5nxTKCEh4AXetrk2kPnJHKR2igVlO88Po5Hp-HBWXS2BMMuF4bCKh32t5jeoLU7MnCzObgqCsrxRfeK3k1Q-cE0CF_Ay5DaHKBR7949xHkkQri2ebFHl_-WJny-q4t5E1WMC0XBm2qnvnjKQz3FQBtPtP8W3jgKyfbap1yDJVv24FXbVPK2ByvDrodbD16P3db5OlR72l6jY6rZCVJves8d5nKRSDfMZQygJ9thqpyyb7iavmwyAwvDTooZEfZyxgq8sgk6Z6pmrqjoBaNoEfazqH4xHJC1oFoV1TuY7H-fDEee67jgmSgMawRkg2Rb-XkS-DZMM4sQxHUaWz-JlbK5tYbHPMs10pLcJIlOMouSOlVc-VwHG7Bczku7CQyJk0HykWcB16EVQiO04Kg8mRqR5v60D1E3ydK4auTUFONCdmFn57JTjiTlSB5IVE4fBgu5q7Yex18lkk6Hsss2RXyU6DL-TdJW7jOvpC8rIbn8wxT7kC0kH1nzs-76tTM0idZC-zeqtPObSiL5imjFl8Z9eN9a4GIOkBcHOAb_8B93_gIro8n4SB79OD78CKt0hv6e-9EnWK6vb-xnpF-13mo-r3s44yuQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Aberrant+Salience%2C+Information+Processing%2C+and+Dopaminergic+Signaling+in+People+at+Clinical+High+Risk+for+Psychosis&rft.jtitle=Biological+psychiatry+%281969%29&rft.au=Howes%2C+Oliver+D.&rft.au=Hird%2C+Emily+J.&rft.au=Adams%2C+Rick+A.&rft.au=Corlett%2C+Philip+R.&rft.date=2020-08-15&rft.issn=0006-3223&rft.volume=88&rft.issue=4&rft.spage=304&rft.epage=314&rft_id=info:doi/10.1016%2Fj.biopsych.2020.03.012&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_biopsych_2020_03_012
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F00063223%2FS0006322319X00165%2Fcov150h.gif