Mortality Secondary to Fulminant Hepatic Failure in Patients with Prior Resolution of Hepatitis B Virus Infection in Japan

Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection was found in 23 (4%) of 552 newly hepatitis B surface antigen-positive patients in Japan. Because one-fourth of cases develop into fulminant hepatic failure and mortality is 100%, management of HBV reactivation in patients...

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Bibliographic Details
Published inCLINICAL INFECTIOUS DISEASES Vol. 47; no. 5; pp. e52 - e56
Main Authors Umemura, Takeji, Tanaka, Eiji, Kiyosawa, Kendo, Kumada, Hiromitsu
Format Journal Article
LanguageEnglish
Published United States The University of Chicago Press 01.09.2008
UNIV CHICAGO PRESS
Subjects
Adult
Aged
Aged, 80 and over
Antiviral Agents - therapeutic use
Female
Hepatitis B - complications
Hepatitis B - drug therapy
Hepatitis B virus
Humans
Japan - epidemiology
Liver Failure, Acute - epidemiology
Liver Failure, Acute - mortality
Male
Middle Aged
Prevalence
Virus Activation
Young Adult
Japan
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ISSN1058-4838
1537-6591
1537-6591
DOI10.1086/590968

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Summary:Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection was found in 23 (4%) of 552 newly hepatitis B surface antigen-positive patients in Japan. Because one-fourth of cases develop into fulminant hepatic failure and mortality is 100%, management of HBV reactivation in patients with resolved HBV infection should be discussed.
Bibliography:ark:/67375/HXZ-VVPZLMWP-4
istex:DA872B1F72881D4C6CBBFB243DD7B556384D8023
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1086/590968