Caspase-3: A Vulnerability Factor and Final Effector in Apoptotic Death of Dopaminergic Neurons in Parkinson's Disease - Hartmann, Andreas; Hunot, Stéphane; Michel, Patrick P.; Muriel, Marie-Paule; Vyas, Sheela; Faucheux, Baptiste A.; Mouatt-Prigent, Annick; Turmel, Hélène; Srinivasan, Anu; Ruberg, Merle; Evan, Gerard I.; Agid, Yves; et al. (Proceedings of the National Academy of Sciences - PNAS, 2000)
Keywords: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology; Aged; Aged, 80 and over; Animals; Antibodies; Apoptosis; Biological Sciences; Blotting, Western; Brain; Brain - enzymology; Brain - ultrastructure; Caspase 3; Caspases - biosynthesis; Caspases - physiology; Cell death; Cells, Cultured; Condensation; Dopamine - metabolism; Dopamine Agents - pharmacology; Enzyme Activation; Humans; Immunohistochemistry; Laboratory staining techniques; Lewy bodies; Male; Mesencephalon; Mesencephalon - enzymology; Mice; Mice, Inbred C57BL; Neurology; Neurons; Neurons - enzymology; Neurons - ultrastructure; Parkinson disease; Parkinson Disease - enzymology; Parkinson Disease - metabolism; Parkinson's disease; Pathology; Rats; Substantia Nigra - enzymology; Tissue Distribution; Ventral Tegmental Area - enzymology