Consumption of high-fat diet induces tumor progression and epithelial–mesenchymal transition of colorectal cancer in a mouse xenograft model - Tang, Feng-Yao; Pai, Man-Hui; Chiang, En-Pei Isabel (The Journal of nutritional biochemistry, 2012)
Keywords: adverse effects; Animals; beta Catenin; beta Catenin - genetics; beta Catenin - metabolism; Biological and medical sciences; Cadherins; Cadherins - genetics; Cadherins - metabolism; Cell Proliferation; Cell Proliferation - drug effects; colon; Colorectal cancer; colorectal neoplasms; Colorectal Neoplasms - pathology; Cyclin D1; Cyclin D1 - genetics; Cyclin D1 - metabolism; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p21 - genetics; Cyclin-Dependent Kinase Inhibitor p21 - metabolism; Cyclooxygenase 2; Cyclooxygenase 2 - genetics; Cyclooxygenase 2 - metabolism; Diet, High-Fat; Diet, High-Fat - adverse effects; Disease Models, Animal; drug effects; epidemiological studies; Epithelial-Mesenchymal Transition; Epithelial-Mesenchymal Transition - drug effects; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; gene expression regulation; Gene Expression Regulation, Neoplastic; genetics; High-fat diet; Histone deacetylase; HT29 Cells; Humans; inflammation; metabolism; Mice; Mice, Inbred BALB C; mitogen-activated protein kinase; Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases - genetics; Mitogen-Activated Protein Kinases - metabolism; NF-kappa B; NF-kappa B - genetics; NF-kappa B - metabolism; pathology; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-Kinase - genetics; Phosphatidylinositol 3-Kinase - metabolism; proliferating cell nuclear antigen; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-akt - genetics; Proto-Oncogene Proteins c-akt - metabolism; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Vertebrates: anatomy and physiology, studies on body, several organs or systems; vimentin; Vimentin - genetics; Vimentin - metabolism; Histone deacetylase; Epithelial–mesenchymal transition; Cyclooxygenase-2; High-fat diet; Colorectal cancer; Animal model; Rectal disease; Cyclooxygenase 2; Heterograft; Tumor progression; Intestinal disease; Histone; Enzyme; Rodentia; Malignant tumor; Feeding; Colonic disease; Epithelial-mesenchymal transition; Vertebrata; Mammalia; Diet; Mouse; Food intake; High-fat diet: Histone deacetylase; Fat; Digestive diseases; Oxidoreductases; Cancer