The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6 - Spencer, Zachary T.; Ng, Victoria H.; Benchabane, Hassina; Siddiqui, Ghalia Saad; Duwadi, Deepesh; Maines, Ben; Bryant, Jamal M.; Schwarzkopf, Anna; Yuan, Kai; Kassel, Sara N.; Mishra, Anant; Pimentel, Ashley; et al. (Nature communications, 2023)
Keywords: 13; 13/1; 13/109; 13/51; 13/89; 13/95; 14/19; 38; 631/136/756; 631/80/86; 631/80/86/2370; 64; 64/24; 96; 96/100; 96/106; Animals; Biology; Cancer; Cell surface; CRISPR; Drosophila - genetics; Drosophila Proteins - metabolism; Homeostasis; Humanities and Social Sciences; Inactivation; Insects; Ligands; multidisciplinary; Mutagenesis; Pattern formation; Physiology; Receptors; Science; Science (multidisciplinary); Sensitivity enhancement; Stabilization; Transcription Factors - metabolism; Tumorigenesis; Ubiquitin; Wnt protein; Wnt Signaling Pathway; Wnt1 Protein - genetics; Wnt1 Protein - metabolism; β-Catenin