Impact of surface grafting density of PEG macromolecules on dually fluorescent silica nanoparticles used for the in vivo imaging of subcutaneous tumors - Adumeau, Laurent; Genevois, Coralie; Roudier, Lydia; Schatz, Christophe; Couillaud, Franck; Mornet, Stéphane (Biochimica et biophysica acta. General subjects, 2017)
Keywords: Animals; Bioengineering; blood circulation; Cell Line, Tumor; Chemical Sciences; EPR effect; fluorescence; fluorescence emission spectroscopy; Fluorescence imaging; fluorescence microscopy; Fluorescent Dyes - administration & dosage; Fluorescent Dyes - chemistry; Fluorescent Dyes - metabolism; image analysis; Imaging; in vivo; Injections, Intravenous; intravenous injection; Life Sciences; liver; Luminescent Measurements; Male; Material chemistry; mice; Mice, Transgenic; Molecular Imaging - methods; monitoring; nanomedicine; Nanomedicine - methods; Nanoparticle; nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - chemistry; Nanoparticles - metabolism; Particle Size; PEGylation; Permeability; Polyethylene Glycols - chemistry; prostatic neoplasms; Prostatic Neoplasms - diagnostic imaging; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; reflectance; silica; Silicon Dioxide - administration & dosage; Silicon Dioxide - chemistry; Silicon Dioxide - metabolism; subcutaneous injection; Surface Properties; Time Factors; Tissue Distribution; transmission electron microscopy; Tumor; zeta potential; RES; EDPS; DMSO; Nanoparticle; EPR; DLS; TFA; MPS; DL800; PEGylation; Tumor; in vivo; Fluorescence imaging; DCC; DL650; DRIFT; DCM; TGA; NPs; i.v; TEOS; PEG; NIR; EPR effect; FRI; TEM; BLI; biodistribution