Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation - Thériault, Sébastien; Li, Zhonglin; Abner, Erik; Luan, Jian’an; Manikpurage, Hasanga D.; Houessou, Ursula; Zamani, Pardis; Briend, Mewen; Boudreau, Dominique K.; Gaudreault, Nathalie; Frenette, Lily; Argaud, Déborah; et al. (Nature communications, 2024)
Keywords: 45/43; 45/91; 49/39; 631/208/199; 631/208/205/2138; 692/4019/592/2727; Aorta; Aortic stenosis; Aortic valve; Aortic Valve - metabolism; Aortic Valve - pathology; Aortic Valve Stenosis - genetics; Blood circulation; Blood pressure; Calcinosis; Gene loci; Gene sequencing; Genes; Genome-wide association studies; Genome-Wide Association Study; Genomic analysis; Genomics; Genotypes; Heart valves; Humanities and Social Sciences; Humans; Lipoproteins; multidisciplinary; Phenotypes; Rheumatic heart disease; Ribonucleic acid; RNA; Science; Science (multidisciplinary); Stenosis; Transcriptomes; Transcriptomics