Multimodal Magnetic Resonance Imaging Assessment of White Matter Aging Trajectories Over the Lifespan of Healthy Individuals - Bartzokis, George; Lu, Po H.; Heydari, Panthea; Couvrette, Alexander; Lee, Grace J.; Kalashyan, Greta; Freeman, Frank; Grinstead, John W.; Villablanca, Pablo; Finn, J. Paul; Mintz, Jim; Alger, Jeffry R.; et al. (Biological psychiatry (1969), 2012)
Keywords: Adolescent; Adult; Adult and adolescent clinical studies; Aged; Aged, 80 and over; Aging; Aging - physiology; Alzheimer; Anisotropy; axial diffusivity; Axons - ultrastructure; Biological and medical sciences; Biomarkers; Brain - anatomy & histology; Brain - growth & development; Cerebral Cortex - anatomy & histology; Cerebral Cortex - growth & development; cognition; degeneration; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; development; diffusion tensor imaging (DTI); Diffusion Tensor Imaging - methods; Echo-Planar Imaging; Female; fractional anisotropy; Humans; Image Processing, Computer-Assisted; magnetic resonance imaging (MRI); Male; Medical sciences; Middle Aged; myelin; Myelin Sheath - physiology; Nerve Degeneration - pathology; Nerve Fibers - ultrastructure; Neurology; oligodendrocytes; Oligodendroglia - physiology; Organic mental disorders. Neuropsychology; Psychiatric/Mental Health; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; radial diffusivity; Reference Values; Regression Analysis; relaxation rate (R2); Relaxation. Biofeedback. Hypnosis. Selfregulation. Meditation; Sex Characteristics; Treatments; white matter (WM); Young Adult; myelin; development; cognition; radial diffusivity; oligodendrocytes; Alzheimer; degeneration; magnetic resonance imaging (MRI); Aging; fractional anisotropy; diffusion tensor imaging (DTI); axial diffusivity; relaxation rate (R2); white matter (WM); relaxation rate (R 2); Senescence; Alzheimer disease; Neuroglia; Multimodal imaging; Cognition; Relaxation; Oligodendrocyte; Development; Degenerative disease; Degeneration; Evaluation; Nervous system diseases; Healthy subject; Myelin; ); Nuclear magnetic resonance imaging; White matter; Cerebral disorder; Diffusion tensor imaging; Treatment; Anisotropy; Central nervous system disease; Medical imagery; relaxation rate (R