Population pharmacokinetic–pharmacodynamic model of elinzanetant based on integrated clinical phase I and II data - Willmann, Stefan; Lloyd, Adam; Austin, Rupert; Joseph, Shiju; Solms, Alexander; Zhang, Yang; Schneider, Annika R. P.; Frechen, Sebastian; Schultze‐Mosgau, Marcus‐Hillert (CPT: pharmacometrics and systems pharmacology, 2024)
Keywords: Administration, Oral; Adult; Aged; Bioavailability; Biological Availability; Breast cancer; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Datasets; Dose-Response Relationship, Drug; Drug dosages; Female; Females; Humans; Male; Menopause; Metabolites; Middle Aged; Models, Biological; Neurokinin-1 Receptor Antagonists - administration & dosage; Neurokinin-1 Receptor Antagonists - pharmacokinetics; Neurokinin-1 Receptor Antagonists - pharmacology; Pharmacodynamics; Pharmacokinetics; Plasma; Womens health; Young Adult