Tumor evolution selectively inactivates the core microRNA machinery for immune evasion - Song, Tian-Yu; Long, Min; Zhao, Hai-Xin; Zou, Miao-Wen; Fan, Hong-Jie; Liu, Yang; Geng, Chen-Lu; Song, Min-Fang; Liu, Yu-Feng; Chen, Jun-Yi; Yang, Yu-Lin; Zhou, Wen-Rong; et al. (Nature communications, 2021)
Keywords: 13/1; 13/109; 13/21; 13/31; 13/44; 13/95; 38/22; 38/23; 38/39; 38/43; 49/90; 49/91; 631/67/1059/2325; 631/67/2329; 631/67/580/1884; 64/60; Animals; Antigen presentation; Antigens; Argonaute 2 protein; Cancer; Cell culture; Cell Line, Tumor; Chemokines - metabolism; CRISPR; Cytokines; Cytotoxicity; Deactivation; Evolution; Gene silencing; Genetic Heterogeneity; Heterogeneity; Humanities and Social Sciences; Humans; Immune Evasion; Immune response; Immune response (cell-mediated); Immune system; Immunosurveillance; Immunotherapy; Inactivation; Interferon; Interferon-gamma; Lymphocytes; Lymphocytes T; Metastases; Mice; Mice, Inbred C57BL; Mice, Nude; MicroRNAs; MicroRNAs - metabolism; miRNA; multidisciplinary; Mutation; Neoplasms - genetics; PD-1 protein; Phosphoprotein Phosphatases; Programmed Cell Death 1 Receptor; Ribonucleic acid; RNA; Science; Science (multidisciplinary); Signal Transduction; Signaling; SOCS-1 protein; Suppressor of Cytokine Signaling 1 Protein; T-Lymphocytes; Toxicity; Tumors; γ-Interferon