CaMKII activation in early diabetic hearts induces altered sarcoplasmic reticulum-mitochondria signaling - Federico, Marilen; Zavala, Maite; Vico, Tamara; López, Sofía; Portiansky, Enrique; Alvarez, Silvia; Abrille, Maria Celeste Villa; Palomeque, Julieta (Scientific reports, 2021)
Keywords: 631/443; 631/443/592; Animals; Arrhythmias, Cardiac - physiopathology; Ca2+/calmodulin-dependent protein kinase II; Calcium (intracellular); Calcium (mitochondrial); Calcium (reticular); Calcium - metabolism; Calcium Signaling - physiology; Calcium-binding protein; Calcium-Binding Proteins - metabolism; Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism; Calmodulin; Cardiomyocytes; Diabetes mellitus; Diabetes Mellitus - physiopathology; Diet; Fusion protein; Heart; Humanities and Social Sciences; Hydrogen peroxide; Hyperactivity; Kinases; Leak channels; Mice; Mice, Transgenic; Mitochondria; Mitochondria - metabolism; Mitochondria - ultrastructure; multidisciplinary; Myocardium; Myocardium - metabolism; Myocardium - pathology; Myocardium - ultrastructure; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - ultrastructure; Oxygen - metabolism; Oxygen consumption; Proteins; Respiration; Retention capacity; Ryanodine; Ryanodine Receptor Calcium Release Channel - metabolism; Ryanodine receptors; Sarcoplasmic reticulum; Sarcoplasmic Reticulum - metabolism; Sarcoplasmic Reticulum - ultrastructure; Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism; Science; Science (multidisciplinary); Transgenic mice; Transmission electron microscopy