Dynamic magnetic resonance imaging of muscle contraction in facioscapulohumeral muscular dystrophy
Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitativel...
Saved in:
| Published in | Scientific reports Vol. 12; no. 1; pp. 7250 - 12 |
|---|---|
| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
04.05.2022
Nature Publishing Group Nature Portfolio |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2045-2322 2045-2322 |
| DOI | 10.1038/s41598-022-11147-2 |
Cover
| Abstract | Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders. |
|---|---|
| AbstractList | Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders. Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders. Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders.Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders. Abstract Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for assessment of the dynamic and elastic muscle properties have not yet been translated into clinics. In this exploratory study, we quantitatively characterized muscle deformation (strain) in patients affected by facioscapulohumeral muscular dystrophy (FSHD), a prevalent muscular dystrophy, by applying dynamic MRI synchronized with neuromuscular electrical stimulation (NMES). We evaluated the quadriceps muscles in 34 ambulatory patients and 13 healthy controls, at 6-to 12-month time intervals. While a subgroup of patients behaved similarly to controls, for another subgroup the median strain decreased over time (approximately 57% over 1.5 years). Dynamic MRI parameters did not correlate with quantitative MRI. Our results suggest that the evaluation of muscle contraction by NMES-MRI is feasible and could potentially be used to explore the elastic properties and monitor muscle involvement in FSHD and other neuromuscular disorders. |
| ArticleNumber | 7250 |
| Author | Faggioli, Arianna Santini, Francesco Monforte, Mauro Germani, Giancarlo Paoletti, Matteo Solazzo, Francesca Pichiecchio, Anna Deligianni, Xeni Ricci, Enzo Bergsland, Niels Savini, Giovanni Tasca, Giorgio |
| Author_xml | – sequence: 1 givenname: Xeni surname: Deligianni fullname: Deligianni, Xeni organization: Radiology, Division of Radiological Physics, University Hospital of Basel, Basel Muscle MRI, Department of Biomedical Engineering, University of Basel – sequence: 2 givenname: Francesco surname: Santini fullname: Santini, Francesco email: francesco.santini@unibas.ch organization: Radiology, Division of Radiological Physics, University Hospital of Basel, Basel Muscle MRI, Department of Biomedical Engineering, University of Basel – sequence: 3 givenname: Matteo surname: Paoletti fullname: Paoletti, Matteo organization: Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation – sequence: 4 givenname: Francesca surname: Solazzo fullname: Solazzo, Francesca organization: School of Specialization in Clinical Pharmacology and Toxicology Center of Research in Medical Pharmacology, School of Medicine, University of Insubria – sequence: 5 givenname: Niels surname: Bergsland fullname: Bergsland, Niels organization: Department of Neurology, Buffalo Neuroimaging Analysis Center, Jacobs School of Medicine and Biomedical Sciences, IRCCS Fondazione Don Carlo Gnocchi ONLUS – sequence: 6 givenname: Giovanni surname: Savini fullname: Savini, Giovanni organization: Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation – sequence: 7 givenname: Arianna surname: Faggioli fullname: Faggioli, Arianna organization: Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation – sequence: 8 givenname: Giancarlo surname: Germani fullname: Germani, Giancarlo organization: Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation – sequence: 9 givenname: Mauro surname: Monforte fullname: Monforte, Mauro organization: Unità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS – sequence: 10 givenname: Enzo surname: Ricci fullname: Ricci, Enzo organization: Unità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS – sequence: 11 givenname: Giorgio surname: Tasca fullname: Tasca, Giorgio organization: Unità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS – sequence: 12 givenname: Anna surname: Pichiecchio fullname: Pichiecchio, Anna organization: Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation, Department of Brain and Behavioral Sciences, University of Pavia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35508609$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9Uk1v1DAUtFARLUv_AAcUiQuXgD-T-IKEylelSlzgbNnPTtarxF7sBGn_Pd5NC20P9cVPzzOjeX7zEp2FGBxCrwl-TzDrPmROhOxqTGlNCOFtTZ-hC4q5qCmj9OxefY4uc97hcgSVnMgX6JwJgbsGywtkPh-CnjxUkx6Cm0uRXI5BB3CVLz0fhir21bRkGF0FMcxJw-xjqHyoeg0-ZtD7ZYzbZXJJjyfkMupU2UOeU9xvD6_Q816P2V3e3hv06-uXn1ff65sf366vPt3UIDiea2ldS52lLbXESAesNRJ4j3vuWjCS27ZjjDLAoA20vDPUSYKJtVhAa_qebdD1qmuj3ql9KvbTQUXt1akR06B0KhOOTmFjNGFCG2sYNz0YrhkRfSeEY9RKKFofV639YiZnwR3nHh-IPnwJfquG-EdJ3HTFVhF4dyuQ4u_F5VlNPoMbRx1cXLKiTYMJpm0ZaoPePoLu4pJC-aqCEmVjuG2Ogm_uO_pn5W6VBdCtAEgx5-R6BX7Wx1UVg35UBKtjcNQaHFWCo07BUbRQ6SPqnfqTJLaScgGHwaX_tp9g_QWsAdg8 |
| CitedBy_id | crossref_primary_10_1016_j_nmd_2025_105274 crossref_primary_10_1016_j_nmd_2022_10_005 crossref_primary_10_1002_jmri_29091 |
| Cites_doi | 10.1002/cmr.b.20184 10.1371/journal.pone.0241832 10.1002/mrm.25312 10.1002/1531-8249(199906)45:6<751::aid-ana9>3.0.co;2-m 10.1007/s00330-015-3890-1 10.1002/mus.25251 10.1002/mrm.26154 10.1016/j.nmd.2015.09.013 10.1002/jcsm.12473 10.1002/ana.24640 10.1186/s12891-021-04134-7 10.1212/WNL.0000000000002640 10.1371/journal.pone.0038779 10.1159/000369343 10.1007/s00415-019-09242-y 10.1002/mus.27074 10.1002/nbm.3459 10.1152/japplphysiol.01337.2013 10.1109/TIP.2017.2713950 10.1007/s00415-016-8361-3 10.1186/1743-0003-11-17 10.1186/s12883-020-01774-5 10.1016/j.apmr.2010.01.019 10.1212/WNL.0000000000000797 10.3389/fneur.2021.630387 10.1007/s13311-018-00675-3 10.1136/jmedgenet-2011-100101 10.1007/s10334-019-00787-7 10.1371/journal.pone.0085416 10.1137/17M1118452 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2022 2022. The Author(s). The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2022 – notice: 2022. The Author(s). – notice: The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88A 88E 88I 8FE 8FH 8FI 8FJ 8FK ABUWG AEUYN AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M2P M7P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA |
| DOI | 10.1038/s41598-022-11147-2 |
| DatabaseName | Springer Nature Open Access Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) ProQuest Health & Medical Collection (NC LIVE) ProQuest Central (purchase pre-March 2016) Biology Database (Alumni Edition) Medical Database (Alumni Edition) Science Database (Alumni Edition) ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) ProQuest Biological Science Collection Health & Medical Collection (Alumni Edition) Medical Database Science Database ProQuest Biological Science Database (NC LIVE) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Biology Journals (Alumni Edition) ProQuest Central ProQuest One Applied & Life Sciences ProQuest One Sustainability ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest Central Basic ProQuest Science Journals ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Publicly Available Content Database MEDLINE - Academic MEDLINE CrossRef |
| Database_xml | – sequence: 1 dbid: C6C name: Springer Nature OA Free Journals url: http://www.springeropen.com/ sourceTypes: Publisher – sequence: 2 dbid: DOA name: Directory of Open Access Journals (DOAJ) url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 3 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 4 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 5 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 2045-2322 |
| EndPage | 12 |
| ExternalDocumentID | oai_doaj_org_article_0bba135abdb34bfcb4a315f855e32d9c PMC9068910 35508609 10_1038_s41598_022_11147_2 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GrantInformation_xml | – fundername: Italian Ministry of Health grantid: RC 2017-2019; RCR 2019; RF-2016-02362914 – fundername: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung grantid: 320030_172876 funderid: http://dx.doi.org/10.13039/501100001711 – fundername: Swiss National Science Foundation grantid: 320030_172876 – fundername: ; grantid: 320030_172876 – fundername: ; grantid: RC 2017-2019; RCR 2019; RF-2016-02362914 |
| GroupedDBID | 0R~ 3V. 4.4 53G 5VS 7X7 88A 88E 88I 8FE 8FH 8FI 8FJ AAFWJ AAJSJ AAKDD ABDBF ABUWG ACGFS ACSMW ACUHS ADBBV ADRAZ AENEX AEUYN AFKRA AJTQC ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI C6C CCPQU DIK DWQXO EBD EBLON EBS ESX FYUFA GNUQQ GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE KQ8 LK8 M0L M1P M2P M48 M7P M~E NAO OK1 PIMPY PQQKQ PROAC PSQYO RNT RNTTT RPM SNYQT UKHRP AASML AAYXX AFPKN CITATION PHGZM PHGZT CGR CUY CVF ECM EIF NPM 7XB 8FK AARCD K9. PJZUB PKEHL PPXIY PQEST PQGLB PQUKI PRINS Q9U 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c540t-9de72ed272d1b9ec37b9c4f0f4e7cb94d783323c0cabc748b2e9101dd05c7bff3 |
| IEDL.DBID | M48 |
| ISSN | 2045-2322 |
| IngestDate | Wed Aug 27 01:29:40 EDT 2025 Thu Aug 21 18:32:25 EDT 2025 Fri Sep 05 03:06:55 EDT 2025 Wed Aug 13 07:01:45 EDT 2025 Thu Jan 02 22:53:54 EST 2025 Thu Apr 24 22:51:39 EDT 2025 Tue Jul 01 04:16:20 EDT 2025 Fri Feb 21 02:40:34 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| License | 2022. The Author(s). Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c540t-9de72ed272d1b9ec37b9c4f0f4e7cb94d783323c0cabc748b2e9101dd05c7bff3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.1038/s41598-022-11147-2 |
| PMID | 35508609 |
| PQID | 2659410760 |
| PQPubID | 2041939 |
| PageCount | 12 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_0bba135abdb34bfcb4a315f855e32d9c pubmedcentral_primary_oai_pubmedcentral_nih_gov_9068910 proquest_miscellaneous_2660102778 proquest_journals_2659410760 pubmed_primary_35508609 crossref_citationtrail_10_1038_s41598_022_11147_2 crossref_primary_10_1038_s41598_022_11147_2 springer_journals_10_1038_s41598_022_11147_2 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2022-05-04 |
| PublicationDateYYYYMMDD | 2022-05-04 |
| PublicationDate_xml | – month: 05 year: 2022 text: 2022-05-04 day: 04 |
| PublicationDecade | 2020 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England |
| PublicationTitle | Scientific reports |
| PublicationTitleAbbrev | Sci Rep |
| PublicationTitleAlternate | Sci Rep |
| PublicationYear | 2022 |
| Publisher | Nature Publishing Group UK Nature Publishing Group Nature Portfolio |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing Group – name: Nature Portfolio |
| References | Gerevini, Scarlato, Maggi (CR10) 2016; 26 Santini, Patil, Scheffler (CR26) 2011; 39B Andersen, Dahlqvist, Vissing (CR8) 2016; 3 Theadom, Rodrigues, Roxburgh (CR2) 2014; 43 Colson, Benchortane, Tanant (CR21) 2010; 91 CR35 CR34 CR31 Hosseini, Plataniotis (CR30) 2017; 26 Hamel, Tawil (CR6) 2018; 15 Deligianni, Hirschmann, Place (CR18) 2020; 15 Wang, Shaw, Faino (CR12) 2021; 22 Leung, Bocchieri, Ahlawat (CR16) 2020 Tasca, Pescatori, Monforte (CR4) 2012; 7 Lassche, Voermans, Schreuder (CR15) 2022 Dahlqvist, Andersen, Khawajazada (CR5) 2019; 266 Janssen, Voet, Geurts (CR9) 2016; 86 Deenen, Arnts, van der Maarel (CR1) 2014; 83 Tasca, Monforte, Ottaviani (CR3) 2016; 79 Gobbo, Maffiuletti, Orizio, Minetto (CR24) 2014; 11 CR29 Santini, Deligianni, Paoletti (CR28) 2021 CR25 Deligianni, Klenk, Place (CR19) 2020 Csapo, Malis, Hodgson, Sinha (CR33) 2014; 116 CR22 Marty, Baudin, Reyngoudt (CR27) 2016; 29 Esposito, Cè, Rampichini (CR20) 2016; 26 Sacconi, Camaño, de Greef (CR7) 2012; 49 Ricci, Galluzzi, Deidda (CR23) 1999; 45 Monforte, Laschena, Ottaviani (CR13) 2019; 10 Sinha, Malis, Csapo (CR32) 2015; 73 Janssen, Voet, Nabuurs (CR11) 2014; 9 Eichinger, Heatwole, Heininger (CR14) 2017; 55 Deligianni, Pansini, Garcia (CR17) 2017; 77 11147_CR22 BH Janssen (11147_CR11) 2014; 9 K Eichinger (11147_CR14) 2017; 55 F Santini (11147_CR26) 2011; 39B 11147_CR25 S Sacconi (11147_CR7) 2012; 49 F Santini (11147_CR28) 2021 X Deligianni (11147_CR18) 2020; 15 G Tasca (11147_CR3) 2016; 79 B Janssen (11147_CR9) 2016; 86 X Deligianni (11147_CR19) 2020 LH Wang (11147_CR12) 2021; 22 R Csapo (11147_CR33) 2014; 116 X Deligianni (11147_CR17) 2017; 77 G Andersen (11147_CR8) 2016; 3 S Gerevini (11147_CR10) 2016; 26 M Monforte (11147_CR13) 2019; 10 MS Hosseini (11147_CR30) 2017; 26 E Ricci (11147_CR23) 1999; 45 11147_CR34 11147_CR31 SS Colson (11147_CR21) 2010; 91 DG Leung (11147_CR16) 2020 F Esposito (11147_CR20) 2016; 26 11147_CR35 JCW Deenen (11147_CR1) 2014; 83 S Lassche (11147_CR15) 2022 M Gobbo (11147_CR24) 2014; 11 JR Dahlqvist (11147_CR5) 2019; 266 J Hamel (11147_CR6) 2018; 15 B Marty (11147_CR27) 2016; 29 G Tasca (11147_CR4) 2012; 7 U Sinha (11147_CR32) 2015; 73 A Theadom (11147_CR2) 2014; 43 11147_CR29 |
| References_xml | – ident: CR22 – volume: 39B start-page: 1 year: 2011 end-page: 10 ident: CR26 article-title: IceLuva: A scripting framework for MR image reconstruction based on free software publication-title: Concepts Magn. Reason. Part B Magn. Reason. Eng. doi: 10.1002/cmr.b.20184 – volume: 15 year: 2020 ident: CR18 article-title: Dynamic MRI of plantar flexion: A comprehensive repeatability study of electrical stimulation-gated muscle contraction standardized on evoked force publication-title: PLoS ONE doi: 10.1371/journal.pone.0241832 – volume: 73 start-page: 1852 year: 2015 end-page: 1863 ident: CR32 article-title: Age-related differences in strain rate tensor of the medial gastrocnemius muscle during passive plantarflexion and active isometric contraction using velocity encoded MR imaging: Potential index of lateral force transmission publication-title: Magn. Reason. Med. doi: 10.1002/mrm.25312 – volume: 45 start-page: 751 year: 1999 end-page: 757 ident: CR23 article-title: Progress in the molecular diagnosis of facioscapulohumeral muscular dystrophy and correlation between the number of KpnI repeats at the 4q35 locus and clinical phenotype publication-title: Ann. Neurol. doi: 10.1002/1531-8249(199906)45:6<751::aid-ana9>3.0.co;2-m – volume: 26 start-page: 693 year: 2016 end-page: 705 ident: CR10 article-title: Muscle MRI findings in facioscapulohumeral muscular dystrophy publication-title: Eur. Radiol. doi: 10.1007/s00330-015-3890-1 – volume: 55 start-page: 333 year: 2017 end-page: 337 ident: CR14 article-title: Validity of the 6 minute walk test in facioscapulohumeral muscular dystrophy publication-title: Muscle Nerve doi: 10.1002/mus.25251 – volume: 77 start-page: 664 year: 2017 end-page: 672 ident: CR17 article-title: Synchronous MRI of muscle motion induced by electrical stimulation publication-title: Magn. Reason. Med. doi: 10.1002/mrm.26154 – volume: 26 start-page: 60 year: 2016 end-page: 72 ident: CR20 article-title: Electromechanical delay components during skeletal muscle contraction and relaxation in patients with myotonic dystrophy type 1 publication-title: Neuromuscul. Disord. doi: 10.1016/j.nmd.2015.09.013 – volume: 10 start-page: 1258 year: 2019 end-page: 1265 ident: CR13 article-title: Tracking muscle wasting and disease activity in facioscapulohumeral muscular dystrophy by qualitative longitudinal imaging publication-title: J. Cachexia Sarcopenia Muscle doi: 10.1002/jcsm.12473 – volume: 79 start-page: 854 year: 2016 end-page: 864 ident: CR3 article-title: Magnetic resonance imaging in a large cohort of facioscapulohumeral muscular dystrophy patients: Pattern refinement and implications for clinical trials publication-title: Ann. Neurol. doi: 10.1002/ana.24640 – volume: 22 start-page: 262 year: 2021 ident: CR12 article-title: Longitudinal study of MRI and functional outcome measures in facioscapulohumeral muscular dystrophy publication-title: BMC Musculoskelet. Disord. doi: 10.1186/s12891-021-04134-7 – ident: CR35 – volume: 86 start-page: 1700 year: 2016 end-page: 1707 ident: CR9 article-title: Quantitative MRI reveals decelerated fatty infiltration in muscles of active FSHD patients publication-title: Neurology doi: 10.1212/WNL.0000000000002640 – ident: CR29 – volume: 7 year: 2012 ident: CR4 article-title: Different molecular signatures in magnetic resonance imaging-staged facioscapulohumeral muscular dystrophy muscles publication-title: PLoS ONE doi: 10.1371/journal.pone.0038779 – volume: 43 start-page: 259 year: 2014 end-page: 268 ident: CR2 article-title: Prevalence of muscular dystrophies: A systematic literature review publication-title: Neuroepidemiology doi: 10.1159/000369343 – ident: CR25 – volume: 266 start-page: 1127 year: 2019 end-page: 1135 ident: CR5 article-title: Relationship between muscle inflammation and fat replacement assessed by MRI in facioscapulohumeral muscular dystrophy publication-title: J. Neurol. doi: 10.1007/s00415-019-09242-y – year: 2022 ident: CR15 article-title: Reduced specific force in patients with mild and severe facioscapulohumeral muscular dystrophy publication-title: Muscle Nerve doi: 10.1002/mus.27074 – volume: 29 start-page: 431 year: 2016 end-page: 443 ident: CR27 article-title: Simultaneous muscle water T2 and fat fraction mapping using transverse relaxometry with stimulated echo compensation publication-title: NMR Biomed. doi: 10.1002/nbm.3459 – volume: 116 start-page: 961 year: 2014 end-page: 969 ident: CR33 article-title: Age-related greater Achilles tendon compliance is not associated with larger plantar flexor muscle fascicle strains in senior women publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.01337.2013 – volume: 26 start-page: 4596 year: 2017 end-page: 4611 ident: CR30 article-title: Derivative kernels: Numerics and applications publication-title: IEEE Trans. Image Process doi: 10.1109/TIP.2017.2713950 – volume: 3 start-page: 438 year: 2016 end-page: 447 ident: CR8 article-title: MRI as outcome measure in facioscapulohumeral muscular dystrophy: 1-year follow-up of 45 patients publication-title: J. Neurol. doi: 10.1007/s00415-016-8361-3 – volume: 11 start-page: 17 year: 2014 ident: CR24 article-title: Muscle motor point identification is essential for optimizing neuromuscular electrical stimulation use publication-title: J. Neuroeng. Rehabil. doi: 10.1186/1743-0003-11-17 – ident: CR31 – year: 2020 ident: CR16 article-title: Longitudinal functional and imaging outcome measures in FKRP limb-girdle muscular dystrophy publication-title: BMC Neurol. doi: 10.1186/s12883-020-01774-5 – volume: 91 start-page: 697 year: 2010 end-page: 702 ident: CR21 article-title: Neuromuscular electrical stimulation training: A safe and effective treatment for facioscapulohumeral muscular dystrophy patients publication-title: Arch. Phys. Med. Rehabil. doi: 10.1016/j.apmr.2010.01.019 – volume: 83 start-page: 1056 year: 2014 end-page: 1059 ident: CR1 article-title: Population-based incidence and prevalence of facioscapulohumeral dystrophy publication-title: Neurology doi: 10.1212/WNL.0000000000000797 – year: 2021 ident: CR28 article-title: Fast open-source toolkit for water T2 mapping in the presence of fat from multi-echo spin-echo acquisitions for muscle MRI publication-title: Front. Neurol. doi: 10.3389/fneur.2021.630387 – ident: CR34 – volume: 15 start-page: 863 year: 2018 end-page: 871 ident: CR6 article-title: Facioscapulohumeral muscular dystrophy: Update on pathogenesis and future treatments publication-title: Neurother. J. Am. Soc. Exp. Neurother. doi: 10.1007/s13311-018-00675-3 – volume: 49 start-page: 41 year: 2012 end-page: 46 ident: CR7 article-title: Patients with a phenotype consistent with facioscapulohumeral muscular dystrophy display genetic and epigenetic heterogeneity publication-title: J. Med. Genet. doi: 10.1136/jmedgenet-2011-100101 – year: 2020 ident: CR19 article-title: Dynamic MR imaging of the skeletal muscle in young and senior volunteers during synchronized minimal neuromuscular electrical stimulation publication-title: Magn. Reason. Mater Phys. Biol. Med. doi: 10.1007/s10334-019-00787-7 – volume: 9 year: 2014 ident: CR11 article-title: Distinct disease phases in muscles of facioscapulohumeral dystrophy patients identified by MR detected fat infiltration publication-title: PLoS ONE doi: 10.1371/journal.pone.0085416 – volume: 22 start-page: 262 year: 2021 ident: 11147_CR12 publication-title: BMC Musculoskelet. Disord. doi: 10.1186/s12891-021-04134-7 – volume: 7 year: 2012 ident: 11147_CR4 publication-title: PLoS ONE doi: 10.1371/journal.pone.0038779 – volume: 49 start-page: 41 year: 2012 ident: 11147_CR7 publication-title: J. Med. Genet. doi: 10.1136/jmedgenet-2011-100101 – volume: 15 year: 2020 ident: 11147_CR18 publication-title: PLoS ONE doi: 10.1371/journal.pone.0241832 – volume: 83 start-page: 1056 year: 2014 ident: 11147_CR1 publication-title: Neurology doi: 10.1212/WNL.0000000000000797 – volume: 91 start-page: 697 year: 2010 ident: 11147_CR21 publication-title: Arch. Phys. Med. Rehabil. doi: 10.1016/j.apmr.2010.01.019 – volume: 45 start-page: 751 year: 1999 ident: 11147_CR23 publication-title: Ann. Neurol. doi: 10.1002/1531-8249(199906)45:6<751::aid-ana9>3.0.co;2-m – ident: 11147_CR29 doi: 10.1137/17M1118452 – ident: 11147_CR34 – volume: 77 start-page: 664 year: 2017 ident: 11147_CR17 publication-title: Magn. Reason. Med. doi: 10.1002/mrm.26154 – volume: 55 start-page: 333 year: 2017 ident: 11147_CR14 publication-title: Muscle Nerve doi: 10.1002/mus.25251 – volume: 26 start-page: 60 year: 2016 ident: 11147_CR20 publication-title: Neuromuscul. Disord. doi: 10.1016/j.nmd.2015.09.013 – volume: 9 year: 2014 ident: 11147_CR11 publication-title: PLoS ONE doi: 10.1371/journal.pone.0085416 – volume: 73 start-page: 1852 year: 2015 ident: 11147_CR32 publication-title: Magn. Reason. Med. doi: 10.1002/mrm.25312 – ident: 11147_CR22 – volume: 15 start-page: 863 year: 2018 ident: 11147_CR6 publication-title: Neurother. J. Am. Soc. Exp. Neurother. doi: 10.1007/s13311-018-00675-3 – volume: 3 start-page: 438 year: 2016 ident: 11147_CR8 publication-title: J. Neurol. doi: 10.1007/s00415-016-8361-3 – volume: 26 start-page: 693 year: 2016 ident: 11147_CR10 publication-title: Eur. Radiol. doi: 10.1007/s00330-015-3890-1 – volume: 39B start-page: 1 year: 2011 ident: 11147_CR26 publication-title: Concepts Magn. Reason. Part B Magn. Reason. Eng. doi: 10.1002/cmr.b.20184 – year: 2020 ident: 11147_CR19 publication-title: Magn. Reason. Mater Phys. Biol. Med. doi: 10.1007/s10334-019-00787-7 – volume: 86 start-page: 1700 year: 2016 ident: 11147_CR9 publication-title: Neurology doi: 10.1212/WNL.0000000000002640 – volume: 29 start-page: 431 year: 2016 ident: 11147_CR27 publication-title: NMR Biomed. doi: 10.1002/nbm.3459 – volume: 266 start-page: 1127 year: 2019 ident: 11147_CR5 publication-title: J. Neurol. doi: 10.1007/s00415-019-09242-y – ident: 11147_CR35 – year: 2021 ident: 11147_CR28 publication-title: Front. Neurol. doi: 10.3389/fneur.2021.630387 – ident: 11147_CR31 – volume: 11 start-page: 17 year: 2014 ident: 11147_CR24 publication-title: J. Neuroeng. Rehabil. doi: 10.1186/1743-0003-11-17 – volume: 79 start-page: 854 year: 2016 ident: 11147_CR3 publication-title: Ann. Neurol. doi: 10.1002/ana.24640 – volume: 43 start-page: 259 year: 2014 ident: 11147_CR2 publication-title: Neuroepidemiology doi: 10.1159/000369343 – volume: 116 start-page: 961 year: 2014 ident: 11147_CR33 publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.01337.2013 – year: 2022 ident: 11147_CR15 publication-title: Muscle Nerve doi: 10.1002/mus.27074 – volume: 10 start-page: 1258 year: 2019 ident: 11147_CR13 publication-title: J. Cachexia Sarcopenia Muscle doi: 10.1002/jcsm.12473 – year: 2020 ident: 11147_CR16 publication-title: BMC Neurol. doi: 10.1186/s12883-020-01774-5 – ident: 11147_CR25 – volume: 26 start-page: 4596 year: 2017 ident: 11147_CR30 publication-title: IEEE Trans. Image Process doi: 10.1109/TIP.2017.2713950 |
| SSID | ssj0000529419 |
| Score | 2.3890364 |
| Snippet | Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging techniques for... Abstract Quantitative muscle MRI (water-T2 and fat mapping) is being increasingly used to assess disease involvement in muscle disorders, while imaging... |
| SourceID | doaj pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 7250 |
| SubjectTerms | 631/1647/245/1628 692/53 692/699/375/374 Dystrophy Elastic properties Electrical stimuli Humanities and Social Sciences Humans Magnetic resonance imaging Magnetic Resonance Imaging - methods multidisciplinary Muscle Contraction Muscle, Skeletal - diagnostic imaging Muscle, Skeletal - pathology Muscles Muscular dystrophy Muscular Dystrophy, Facioscapulohumeral - diagnostic imaging Muscular Dystrophy, Facioscapulohumeral - pathology Neuromuscular diseases Neuromuscular electrical stimulation Quadriceps Muscle Science Science (multidisciplinary) |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEBYlUOiltE0fTpOiQm-tiSzJlnRskoZQaE8N5Cb0bBaydojXh_z7jiTvNtvnJVdLgmEe1oxm5huE3hFpusAIqaXNTze8q5WMsZahs7DgLMlTIr587c7O-eeL9uLOqK9UE1bggQvjDom1pmGtsd4ybqOz3LCmjbJtA6NeufT3JYrcCaYKqjdVvFFzlwxh8nCEmyp1k0HsBead4Am2bqIM2P8nL_P3YslfMqb5Ijp9gh7PHiT-WCh_ih6E_hl6WGZK3u4ie1JmzOOl-d6nDkUMAfWQYDUCXizzTCI8RLycRjiNc6V66W3Aix5H4xbD6Mz1dDVcTvm9Ku9MtarY346rmwHE8hydn376dnxWz4MUagcO2apWPggaPBXUN1YFx4RVjkcSeRDOKu6FZIwyR5yxTnAQWwAvovGetE7YGNkLtNMPfXiFsDBg5EQYF8APiYFbYT14HSLGpvEt6yrUrJmq3YwynoZdXOmc7WZSF0FoEITOgtC0Qu83Z64LxsY_dx8lWW12Jnzs_AG0Rs9ao_-nNRXaX0taz0Y7atq1oDQpVVmht5tlMLeUQzF9GKa0J0WwVAhZoZdFMTaUgOsGASJRFRJbKrNF6vZKv7jMkN6KdBJYXqEPa-X6SdbfWbF3H6x4jR7RZBWpiJPvo53VzRQOwNFa2TfZpn4AZvYnIw priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Health & Medical Collection (NC LIVE) dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagCIkL4k3agozEDaI6sRPbJ8SrqpDgRKW9WX62K3WTZbM59N8zdryplkev8VhyPDP2eB7fIPSWCN16SkgpTHLdsLaUIoRS-NbAgDUkdYn4_qM9O2ffFs0iO9yGnFa5OxPTQe16G33kJ3XbSFbFONKH9a8ydo2K0dXcQuMuupegy0Ce-YLPPpYYxWKVzLUyhIqTAe6rWFMGLzBQ8ghSsHcfJdj-f9maf6dM_hE3TdfR6SP0MNuR-OPE-Mfoju-eoPtTZ8nrp8h8mTrN45W-6GKdIoZndR_BNTxerlJnItwHvBoHmI1TvvpU4YCXHQ7aLvvB6vV41V-OyWuVKGPGKnbXw3bTA3OeofPTrz8_n5W5nUJpwSzbltJ5XntX89pVRnpLuZGWBRKY59ZI5rigtKaWWG0sZ8A8D7ZE5RxpLDch0OfooOs7_xJhrkHVCdfWgzUSPDPcOLA9eAhV5RraFqjabaqyGWs8try4UinmTYWaGKGAESoxQtUFejfPWU9IG7dSf4q8mikjSnb60G8uVFY6RYzRFW20cYYyE6xhmlZNEE3jae2kLdDxjtMqq-6gbgStQG_mYVC6GEnRne_HSBPfsTXnokAvJsGYVwIGHDwTiSwQ3xOZvaXuj3TLywTsLUkrYMsL9H4nXDfL-v9WHN7-F0foQR3lPSZpsmN0sN2M_hUYUlvzOmnLb-pPHTU priority: 102 providerName: ProQuest – databaseName: Springer Nature Open Access Journals dbid: C6C link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3Nb9UwDLfGEBIXxPcKAwWJG1SkSdqkR3gwTUhwYtJuVT63J-210-vrYf89TvqBHgwkro0jWbHd2LH9M8BbqnTlOaW5MunpRlR5rULIla8MLlhD05SIb9-r0zPx9bw8PwA298Kkov0EaZl-03N12IceL5rYDIahE1pnRBe4A3cVxnURL39VrZZ3lZi5EkU99cdQrm7ZuncHJaj-2_zLP8skf8uVpivo5CE8mHxH8nHk9hEc-PYx3BunSd48AfN5nC5PNvqijb2JBEPpLgJqeLLepGlEpAtkM_S4m6Qa9bGrgaxbErRdd73V18NVdzmkl6pEGatUibvpd9sOBfIUzk6-_Fid5tMIhdyiK7bLa-cl845J5gpTe8ulqa0INAgvramFk4pzxi212lgpUGAe_YfCOVpaaULgz-Cw7Vp_BERqNG8qtfXogQQvjDQO_Q0ZQlG4klcZFPOhNnbCF49jLq6alOfmqhkF0aAgmiSIhmXwbtlzPaJr_JP6U5TVQhmRsdOHbnvRTJrSUGN0wUttnOHCBGuE5kUZVFl6zlxtMzieJd1M5to3rCpRaWKSMoM3yzIaWsye6NZ3Q6SJsSuTUmXwfFSMhRN02jA0pHUGck9l9ljdX2nXlwnMu6aVwiPP4P2sXL_Y-vtRvPg_8pdwn0X9j4Wa4hgOd9vBv0JnamdeJ-v5CUmSGvc priority: 102 providerName: Springer Nature |
| Title | Dynamic magnetic resonance imaging of muscle contraction in facioscapulohumeral muscular dystrophy |
| URI | https://link.springer.com/article/10.1038/s41598-022-11147-2 https://www.ncbi.nlm.nih.gov/pubmed/35508609 https://www.proquest.com/docview/2659410760 https://www.proquest.com/docview/2660102778 https://pubmed.ncbi.nlm.nih.gov/PMC9068910 https://doaj.org/article/0bba135abdb34bfcb4a315f855e32d9c |
| Volume | 12 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Zb9NAEB71EKgviLMYSrRIvIHB9q699gNCaWhVRWqFgEh5s_ZsIyV2ySGRf8_s2g4EUp4s7SGtdmY83-xcAG-iXGSGRlGYS_90w7KwyK0Nc5NJnFAy8l0iLq-yixEbjtPxHnTtjtoLXOw07Vw_qdF8-v7nj_UnFPiPTcp4_mGBSsgliqFZhZLrKg_swyFqpswZY5ct3G9qfScFi4s2d2b31iO4jyoYgb4LUfxDVfmK_rtg6L_RlH-5VL2mOn8ID1qISfoNTzyCPVM9hntN08n1E5Cfmyb0ZCauK5fCSNDirl3dDUMmM9-0iNSWzFYL3E18KHuT_EAmFbFCTeqFEreraX2z8g9afqULZiV6vVjOa6TbUxidn30fXIRtp4VQIWJbhoU2PDE64YmOZWEU5bJQzEaWGa5kwTTPKU2oipSQijOkq0GYEWsdpYpLa-kzOKjqyjwHwgX-BSIulEGgYg2TXGqEJdzaONYpzQKIu0stVVuG3HXDmJbeHU7zsqFJiTQpPU3KJIC3mz23TRGO_64-dbTarHQFtP1APb8uW3ksIylFTFMhtaRMWiWZoHFq8zQ1NNGFCuCko3TZMWWZZCnyj_NlBvB6M43y6JwsojL1yq1xJm7CeR7AccMYm5N0jBUA32KZraNuz1STG1_zu4iyHK88gHcdc_0-1t1X8eLOI7yEo8RxvQvdZCdwsJyvzCuEV0vZg30-5j047PeH34b4PT27-vIVRwfZoOefLHpeqn4B_58mIQ |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Jb9QwFLZKEYILYidQwEhwgqiO7cTJASGgVFO6nFqpN-O1HamTDJMZoflT_EaenWSqYemt19iJHL_F7_ktH0JvSKkKxwhJSx2vbniRVqX3aekKDQNGk4gScXhUjE74t9P8dAP9GmphQlrloBOjoraNCXfk27TIK56FONLH6Y80oEaF6OoAodGxxb5b_gSXrf2wtwP0fUvp7tfjL6O0RxVIDVgn87SyTlBnqaA205UzTOjKcE88d8LoiltRMkaZIUZpIzj8g4MjNbOW5EZo7xl89wa6yRnYViA_4lSs7nRC1IxnVV-bQ1i53cL5GGrYwOMDpRKaIqydfxEm4F-27d8pmn_EaePxt3sP3e3tVvypY7T7aMPVD9CtDsly-RDpnQ7ZHk_UWR3qIjG48U1o5uHweBKRkHDj8WTRwts45sd3FRV4XGOvzLhpjZouLprzRbwlizNDhiy2y3Y-a4AZHqGTa9nox2izbmr3FGGhQLUQoYwD68c7roW2YOsI77PM5qxIUDZsqjR9b_MAsXEhY4ydlbIjhARCyEgISRP0bvXOtOvsceXsz4FWq5mhK3d80MzOZC_kkmitMpYrbTXj2hvNFctyX-a5Y9RWJkFbA6VlrypaecnYCXq9GgYhD5EbVbtmEeYEv5kKUSboSccYq5WAwQhuKakSJNZYZm2p6yP1-Dw2Eq9IUcKWJ-j9wFyXy_r_Vjy7-i9eoduj48MDebB3tP8c3aGB90OCKN9Cm_PZwr0AI26uX0bJwej7dYvqb3HZW8E |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1bb9MwFLZGJxAviDuBAUaCJ4jq2E6cPEyI0VUbg2pCTNpb8HWrtCalaYX6F_lVHDtpp3LZ215jJ3J8js_F5_Ih9JrkMrOMkDhX4eqGZ3GROxfnNlMwoBUJKBFfRtnBCf90mp5uoV-rWhifVrmSiUFQm1r7O_I-zdKCJz6O1HddWsTxYPh--iP2CFI-0rqC05AdzILZDe3GuiKPI7v8Ce5cs3s4ANq_oXS4_-3jQdwhDsQaLJd5XBgrqDVUUJOowmomVKG5I45boVXBjcgZo0wTLZUWHP7PgrpNjCGpFso5Bt-9gbYFaEnaQ9t7-6Pjr-sbHx9T40nRVe4Qlvcb0J6-wg38QRA5vmXChnYMIAL_snz_TuD8I4oblOPwLrrTWbX4Q8uG99CWre6jmy3O5fIBUoMW9x5P5FnlqyYxOPm1b_Vh8XgScJJw7fBk0cDbOGTPt_UWeFxhJ_W4brScLi7q80W4Qwszff4sNstmPquBVR6ik2vZ6keoV9WVfYKwkCB4iJDagm3kLFdCGbCEhHNJYlKWRShZbWqpu87nHoDjogwReJaXLSFKIEQZCFHSCL1dvzNt-35cOXvP02o90_fsDg_q2VnZiYCSKCUTlkplFOPKacUlS1KXp6ll1BQ6QjsrSpedIGnKS7aP0Kv1MIgAH9eRla0Xfo73qqkQeYQet4yxXgmYk-C0kiJCYoNlNpa6OVKNz0Ob8YJkOWx5hN6tmOtyWf_fiqdX_8VLdAuObfn5cHT0DN2mnvV99ijfQb35bGGfg4U3Vy-6o4PR9-s-rb8BWqlmgw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dynamic+magnetic+resonance+imaging+of+muscle+contraction+in+facioscapulohumeral+muscular+dystrophy&rft.jtitle=Scientific+reports&rft.au=Deligianni%2C+Xeni&rft.au=Santini%2C+Francesco&rft.au=Paoletti%2C+Matteo&rft.au=Solazzo%2C+Francesca&rft.date=2022-05-04&rft.eissn=2045-2322&rft.volume=12&rft.issue=1&rft.spage=7250&rft_id=info:doi/10.1038%2Fs41598-022-11147-2&rft_id=info%3Apmid%2F35508609&rft.externalDocID=35508609 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2045-2322&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2045-2322&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2045-2322&client=summon |