A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation - Hughes, J.L.; Jones, P.S.; Beech, J.S.; Wang, D.; Menon, D.K.; Aigbirhio, F.I.; Fryer, T.D.; Baron, J.C. (NeuroImage (Orlando, Fla.), 2012)
Keywords: Animals; Antibodies; Biomedical research; Brain Mapping - methods; CD11b Antigen; Cerebrovascular Circulation - physiology; Image Processing, Computer-Assisted; Immunohistochemistry; Infarction, Middle Cerebral Artery - pathology; Ischemia; Ischemic Attack, Transient - diagnostic imaging; Ischemic Attack, Transient - pathology; Isoquinolines; Ligands; Macrophage Activation - physiology; Male; Microglia - physiology; PBR; Peripheral benzodiazepine receptor; PET; Positron-Emission Tomography - methods; Radiopharmaceuticals; Rats; Rats, Inbred SHR; Receptors, GABA-A - metabolism; Reproducibility of Results; Rodents; Stroke; Studies; Tissue Fixation; TSPO: neuroinflammation; Peripheral benzodiazepine receptor; PBR; Stroke; TSPO: neuroinflammation; PET