Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes - Ansari-Pour, Naser; Zheng, Yonglan; Yoshimatsu, Toshio F.; Sanni, Ayodele; Ajani, Mustapha; Reynier, Jean-Baptiste; Tapinos, Avraam; Pitt, Jason J.; Dentro, Stefan; Woodard, Anna; Rajagopal, Padma Sheila; Fitzgerald, Dominic; et al. (Nature communications, 2021)
Keywords: 45; 45/23; 45/91; 631/114/2785; 631/67/69; 692/4028/67/1347; Adult; Aged; Biomarkers, Tumor - genetics; Biopsy; Black People - ethnology; Black People - genetics; Breast - pathology; Breast cancer; Breast Neoplasms - ethnology; Breast Neoplasms - genetics; Breast Neoplasms - mortality; Breast Neoplasms - pathology; Clonal Evolution; DNA Mutational Analysis; Ethnic factors; Evolution; Female; GATA-3 protein; GATA3 Transcription Factor - genetics; Gene sequencing; Genetic Heterogeneity; Genomes; Genomic Instability; Genomics; Germ-Line Mutation; Health Status Disparities; Heterogeneity; Homologous recombination; Homology; Humanities and Social Sciences; Humans; Medical research; Middle Aged; multidisciplinary; Mutation; Nigeria - epidemiology; Nigeria - ethnology; Patients; Risk Assessment; RNA-Seq; Science; Science (multidisciplinary); Synaptophysin - genetics; Trans-Activators - genetics; Transcriptomes; Tumor Microenvironment - genetics; Tumors; White People - ethnology; White People - genetics; Whole Genome Sequencing; Nigeria