Narciclasine improves outcome in sepsis among neonatal rats via inhibition of calprotectin and alleviating inflammatory responses - Kingsley, Manoj Kumar; Bhat, Ballambattu Vishnu; Badhe, Bhawana Ashok; Dhas, Benet Bosco; Parija, Subhash Chandra (Scientific reports, 2020)
Keywords: 13/21; 13/51; 14/63; 38; 631/250/255/3192; 631/250/256/1980; 64; 82/29; 82/80; Acute Lung Injury - blood; Acute Lung Injury - drug therapy; Acute Lung Injury - pathology; Adaptor proteins; Amaryllidaceae Alkaloids - pharmacology; Amaryllidaceae Alkaloids - therapeutic use; Anemia - complications; Animal models; Animals; Animals, Newborn; Anti-inflammatory agents; Bacterial Load; Biodegradation; Cytokines; Humanities and Social Sciences; Inflammation; Inflammation - blood; Inflammation - complications; Inflammation - drug therapy; Inflammation - pathology; Inflammation Mediators - blood; Interleukin 1; Interleukin-6 - metabolism; IRAK protein; Kinases; Leukocyte L1 Antigen Complex - metabolism; Liver; Liver - injuries; Liver - pathology; Morbidity; multidisciplinary; MyD88 protein; Neonates; Phenanthridines - pharmacology; Phenanthridines - therapeutic use; Phosphorylation; Phosphorylation - drug effects; Plasma levels; Rats; S100 Proteins - blood; S100 Proteins - metabolism; Science; Science (multidisciplinary); Sepsis; Sepsis - blood; Sepsis - complications; Sepsis - drug therapy; Sepsis - microbiology; Signal transduction; Signal Transduction - drug effects; Survival Analysis; Synaptotagmin; Toll-Like Receptor 4 - metabolism; Toll-like receptors; TRAF6 protein; Transcription Factor RelA - metabolism; Treatment Outcome; Tumor necrosis factor; Tumor necrosis factor receptors; Tumor Necrosis Factor-alpha - metabolism