Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials - Pesic, Marija; Stöhr, Thomas; Ossig, Joachim; Borkett, Keith; Donsbach, Martin; Dao, Van-Anh; Webster, Lynn; Schippers, Frank (Drugs in R&D, 2020)
Keywords: Administration, Oral; Adult; Alcohol; Alcoholic Beverages - adverse effects; Benzodiazepines; Benzodiazepines - administration & dosage; Benzodiazepines - adverse effects; Benzodiazepines - pharmacokinetics; Bioavailability; Biological Availability; Body mass index; Clinical trials; Consciousness; Cytochrome; Drug dosages; Enzymes; Female; Females; Healthy Volunteers; Humans; Hypnotics and Sedatives - administration & dosage; Hypnotics and Sedatives - adverse effects; Hypnotics and Sedatives - pharmacokinetics; Internal Medicine; Medicine; Medicine & Public Health; Metabolic Clearance Rate; Middle Aged; Original; Original Research Article; Pharmacodynamics; Pharmacokinetics; Pharmacology/Toxicology; Pharmacotherapy; Plasma; Prescription Drug Misuse; Sex crimes; Sex Offenses - prevention & control; Young Adult