The Epidemiology of Oral HPV Infection among a Multinational Sample of Healthy Men
Background: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men. Methods: Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the U...
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| Published in | Cancer epidemiology, biomarkers & prevention Vol. 20; no. 1; pp. 172 - 182 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Philadelphia, PA
American Association for Cancer Research
01.01.2011
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1055-9965 1538-7755 1538-7755 |
| DOI | 10.1158/1055-9965.EPI-10-0682 |
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| Abstract | Background: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.
Methods: Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array.
Results: Oral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%–5.0%) β-globin–positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%–2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%–1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (Ptrend = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4–4.4). Oral sexual behaviors were not associated with oral HPV infection.
Conclusions: Oral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use.
Impact: Oral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. ∼40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites. Cancer Epidemiol Biomarkers Prev; 20(1); 172–82. ©2011 AACR. |
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| AbstractList | Background: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.
Methods: Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array.
Results: Oral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%–5.0%) β-globin–positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%–2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%–1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (Ptrend = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4–4.4). Oral sexual behaviors were not associated with oral HPV infection.
Conclusions: Oral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use.
Impact: Oral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. ∼40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites. Cancer Epidemiol Biomarkers Prev; 20(1); 172–82. ©2011 AACR. BACKGROUND: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men. METHODS: Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array. RESULTS: Oral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%-5.0%) beta -globin-positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%-2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%-1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (Ptrend = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4-4.4). Oral sexual behaviors were not associated with oral HPV infection. CONCLUSIONS: Oral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use. IMPACT: Oral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. similar to 40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites. Cancer Epidemiol Biomarkers Prev; 20(1); 172-82. [copy ]2011 AACR. Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men. Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array. Oral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%-5.0%) β-globin-positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%-2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%-1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (P(trend) = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4-4.4). Oral sexual behaviors were not associated with oral HPV infection. Oral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use. Oral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. ∼40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites. Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.BACKGROUNDOral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.Oral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array.METHODSOral rinse/gargle specimens and questionnaire data were collected from 1,688 healthy men aged 18 to 74 (median = 31 years), from the United States, Mexico, and Brazil. HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59, and noncarcinogenic HPV types were detected using Roche Linear Array.Oral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%-5.0%) β-globin-positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%-2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%-1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (P(trend) = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4-4.4). Oral sexual behaviors were not associated with oral HPV infection.RESULTSOral HPV DNA was detected in 67 of 1,680 (4.0%, 95% CI = 3.1%-5.0%) β-globin-positive specimens; carcinogenic HPVs were detected in 1.3% (95% CI = 0.8%-2.0%; n = 22) and HPV16 was the most commonly detected carcinogenic HPV type (0.6%, 95% CI = 0.2%-1.1%; n = 10). The prevalence of oral HPV infection was similar by country except for HPV55, which had notably higher prevalence in Mexico (3.0%) than Brazil (0%) or the United States (0.2%). Oral HPV prevalence nonsignificantly increased over increasing age categories (P(trend) = 0.096). The strongest predictor of oral HPV was current tobacco use, which increased the odds 2.5-fold (95% CI = 1.4-4.4). Oral sexual behaviors were not associated with oral HPV infection.Oral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use.CONCLUSIONSOral HPV16 infection was rare in healthy men, especially at younger ages, and was positively associated with current tobacco use.Oral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. ∼40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites.IMPACTOral HPV appears to be about 10-fold less prevalent than infection at genital sites in men (4% vs. ∼40%, respectively). It remains unclear whether this reflects reduced exposure or if the oral region is more resistant to HPV infection compared with anogenital sites. |
| Author | Smith, Danelle Papenfuss, Mary Kreimer, Aimee R. Villa, Alessandro Hildesheim, Allan Giuliano, Anna R. Abrahamsen, Martha Villa, Luisa L. Nyitray, Alan G. Lazcano-Ponce, Eduardo |
| AuthorAffiliation | 1 National Cancer Institute, NIH, Bethesda, Maryland 4 Instituto Nacional de Salud Pública, Cuernavaca, México 2 H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 3 Ludwig Institute for Cancer Research, São Paulo, Brazil |
| AuthorAffiliation_xml | – name: 1 National Cancer Institute, NIH, Bethesda, Maryland – name: 2 H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL – name: 4 Instituto Nacional de Salud Pública, Cuernavaca, México – name: 3 Ludwig Institute for Cancer Research, São Paulo, Brazil |
| Author_xml | – sequence: 1 givenname: Aimee R. surname: Kreimer fullname: Kreimer, Aimee R. – sequence: 2 givenname: Alessandro surname: Villa fullname: Villa, Alessandro – sequence: 3 givenname: Alan G. surname: Nyitray fullname: Nyitray, Alan G. – sequence: 4 givenname: Martha surname: Abrahamsen fullname: Abrahamsen, Martha – sequence: 5 givenname: Mary surname: Papenfuss fullname: Papenfuss, Mary – sequence: 6 givenname: Danelle surname: Smith fullname: Smith, Danelle – sequence: 7 givenname: Allan surname: Hildesheim fullname: Hildesheim, Allan – sequence: 8 givenname: Luisa L. surname: Villa fullname: Villa, Luisa L. – sequence: 9 givenname: Eduardo surname: Lazcano-Ponce fullname: Lazcano-Ponce, Eduardo – sequence: 10 givenname: Anna R. surname: Giuliano fullname: Giuliano, Anna R. |
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| Cites_doi | 10.1097/00007435-199904001-00002 10.1097/OLQ.0b013e3181c94a3b 10.1086/514052 10.1158/1055-9965.EPI-05-0460 10.1128/JCM.36.10.3020-3027.1998 10.1056/NEJMoa065497 10.1086/597755 10.1158/1055-9965.EPI-04-0551 10.1158/1055-9965.EPI-09-0983 10.1016/S1473-3099(07)70158-5 10.1158/1055-9965.EPI-05-0983 10.1093/oxfordjournals.jncimonographs.a003477 10.1158/1055-9965.EPI-08-0151 10.1016/j.virol.2005.04.002 10.1093/aje/kwp225 10.1093/jnci/94.18.1406 10.1086/381504 10.1002/cncr.22963 10.1016/S1470-2045(09)70096-8 10.1111/j.1600-0714.2007.00556.x 10.1002/ijc.21731 10.1097/INF.0b013e318124a4ae 10.1002/ijc.24097 10.1128/JCM.38.1.357-361.2000 10.1093/jnci/djn025 10.1023/A:1020668232219 10.1128/JCM.43.11.5526-5535.2005 |
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| PublicationTitle | Cancer epidemiology, biomarkers & prevention |
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| PublicationYear | 2011 |
| Publisher | American Association for Cancer Research |
| Publisher_xml | – name: American Association for Cancer Research |
| References | Kreimer (2022060919565960600_bib5) 2010; 37 D'Souza (2022060919565960600_bib4) 2007; 356 Castellsague (2022060919565960600_bib18) 1997; 176 Montaldo (2022060919565960600_bib7) 2007; 36 Bouvard (2022060919565960600_bib2) 2009; 10 Smith (2022060919565960600_bib8) 2007; 26 Nyitray (2022060919565960600_bib14) 2010 Hernandez (2022060919565960600_bib15) 2005; 14 Giuliano (2022060919565960600_bib9) 2008; 17 Gravitt (2022060919565960600_bib11) 1998; 36 Proia (2022060919565960600_bib21) 2006; 15 Vaccarella (2022060919565960600_bib28) 2010; 19 De Sanjose (2022060919565960600_bib13) 2007; 7 Castle (2022060919565960600_bib23) 2002; 94 Franceschi (2022060919565960600_bib17) 2002 Schiffman (2022060919565960600_bib26) 2005; 337 Cates (2022060919565960600_bib29) 1999; 26 D'Souza (2022060919565960600_bib10) 2005; 43 D'Souza (2022060919565960600_bib20) 2009; 199 Giuliano (2022060919565960600_bib24) 2002; 13 Sturgis (2022060919565960600_bib30) 2007; 110 Gravitt (2022060919565960600_bib12) 2000; 38 Parkin (2022060919565960600_bib1) 2006; 118 Nyitray (2022060919565960600_bib25) 2009; 170 Kreimer (2022060919565960600_bib6) 2004; 189 Giuliano (2022060919565960600_bib16) 2009; 124 Chaturvedi (2022060919565960600_bib27) 2010 Gillison (2022060919565960600_bib19) 2008; 100 Castellsague (2022060919565960600_bib22) 2003 Kreimer (2022060919565960600_bib3) 2005; 14 |
| References_xml | – volume: 26 start-page: S2 year: 1999 ident: 2022060919565960600_bib29 article-title: Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. American Social Health Association Panel publication-title: Sex Transm Dis doi: 10.1097/00007435-199904001-00002 – volume: 37 start-page: 386 year: 2010 ident: 2022060919565960600_bib5 article-title: Oral human papillomavirus in healthy individuals: a systematic review of the literature publication-title: Sex Transm Dis doi: 10.1097/OLQ.0b013e3181c94a3b – volume: 176 start-page: 353 year: 1997 ident: 2022060919565960600_bib18 article-title: Prevalence of penile human papillomavirus DNA in husbands of women with and without cervical neoplasia: a study in Spain and Colombia publication-title: J Infect Dis doi: 10.1086/514052 – volume: 14 start-page: 2550 year: 2005 ident: 2022060919565960600_bib15 article-title: Anal human papillomavirus infection in women and its relationship with cervical infection publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-05-0460 – year: 2010 ident: 2022060919565960600_bib27 article-title: Oral and anal HPV infection among HIV-infected men and women – volume: 36 start-page: 3020 year: 1998 ident: 2022060919565960600_bib11 article-title: Genotyping of 27 human papillomavirus types by using L1 consensus PCR products by a single-hybridization, reverse line blot detection method publication-title: J Clin Microbiol doi: 10.1128/JCM.36.10.3020-3027.1998 – volume: 356 start-page: 1944 year: 2007 ident: 2022060919565960600_bib4 article-title: Case-control study of human papillomavirus and oropharyngeal cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa065497 – start-page: 1498 volume-title: J Infect Dis year: 2010 ident: 2022060919565960600_bib14 article-title: Prevalence of and risk factors for anal human papillomavirus infection in men who have sex with women: a cross-national study – volume: 199 start-page: 1263 year: 2009 ident: 2022060919565960600_bib20 article-title: Oral sexual behaviors associated with prevalent oral human papillomavirus infection publication-title: J Infect Dis doi: 10.1086/597755 – start-page: 705 volume-title: Br J Cancer year: 2002 ident: 2022060919565960600_bib17 article-title: Prevalence and determinants of human papillomavirus genital infection in men – volume: 14 start-page: 467 year: 2005 ident: 2022060919565960600_bib3 article-title: Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-04-0551 – volume: 19 start-page: 503 year: 2010 ident: 2022060919565960600_bib28 article-title: Concurrent infection with multiple human papillomavirus types: pooled analysis of the IARC HPV Prevalence Surveys publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-09-0983 – volume: 7 start-page: 453 year: 2007 ident: 2022060919565960600_bib13 article-title: Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis publication-title: Lancet Infect Dis doi: 10.1016/S1473-3099(07)70158-5 – volume: 15 start-page: 1061 year: 2006 ident: 2022060919565960600_bib21 article-title: Smoking and smokeless tobacco-associated human buccal cell mutations and their association with oral cancer—a review publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-05-0983 – start-page: 20 year: 2003 ident: 2022060919565960600_bib22 article-title: Cofactors in human papillomavirus carcinogenesis–role of parity, oral contraceptives, and tobacco smoking publication-title: J Natl Cancer Inst Monogr doi: 10.1093/oxfordjournals.jncimonographs.a003477 – volume: 17 start-page: 2036 year: 2008 ident: 2022060919565960600_bib9 article-title: The human papillomavirus infection in men study: human papillomavirus prevalence and type distribution among men residing in Brazil, Mexico, and the United States publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-08-0151 – volume: 337 start-page: 76 year: 2005 ident: 2022060919565960600_bib26 article-title: The carcinogenicity of human papillomavirus types reflects viral evolution publication-title: Virology doi: 10.1016/j.virol.2005.04.002 – volume: 170 start-page: 965 year: 2009 ident: 2022060919565960600_bib25 article-title: Test-retest reliability of a sexual behavior interview for men residing in Brazil, Mexico, and the United States: the HPV in Men (HIM) Study publication-title: Am J Epidemiol doi: 10.1093/aje/kwp225 – volume: 94 start-page: 1406 year: 2002 ident: 2022060919565960600_bib23 article-title: A prospective study of high-grade cervical neoplasia risk among human papillomavirus-infected women publication-title: J Natl Cancer Inst doi: 10.1093/jnci/94.18.1406 – volume: 189 start-page: 686 year: 2004 ident: 2022060919565960600_bib6 article-title: Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatus publication-title: J Infect Dis doi: 10.1086/381504 – volume: 110 start-page: 1429 year: 2007 ident: 2022060919565960600_bib30 article-title: Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? publication-title: Cancer doi: 10.1002/cncr.22963 – volume: 10 start-page: 321 year: 2009 ident: 2022060919565960600_bib2 article-title: A review of human carcinogens–Part B: biological agents publication-title: Lancet Oncol doi: 10.1016/S1470-2045(09)70096-8 – volume: 36 start-page: 482 year: 2007 ident: 2022060919565960600_bib7 article-title: Detection and genotyping of human papillomavirus DNA in samples from healthy Sardinian patients: a preliminary study publication-title: J Oral Pathol Med doi: 10.1111/j.1600-0714.2007.00556.x – volume: 118 start-page: 3030 year: 2006 ident: 2022060919565960600_bib1 article-title: The global health burden of infection-associated cancers in the year 2002 publication-title: Int J Cancer doi: 10.1002/ijc.21731 – volume: 26 start-page: 836 year: 2007 ident: 2022060919565960600_bib8 article-title: Prevalence of human papillomavirus in the oral cavity/oropharynx in a large population of children and adolescents publication-title: Pediatr Infect Dis J doi: 10.1097/INF.0b013e318124a4ae – volume: 124 start-page: 1251 year: 2009 ident: 2022060919565960600_bib16 article-title: Circumcision and sexual behavior: factors independently associated with human papillomavirus detection among men in the HIM study publication-title: Int J Cancer doi: 10.1002/ijc.24097 – volume: 38 start-page: 357 year: 2000 ident: 2022060919565960600_bib12 article-title: Improved amplification of genital human papillomaviruses publication-title: J Clin Microbiol doi: 10.1128/JCM.38.1.357-361.2000 – volume: 100 start-page: 407 year: 2008 ident: 2022060919565960600_bib19 article-title: Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djn025 – volume: 13 start-page: 839 year: 2002 ident: 2022060919565960600_bib24 article-title: Clearance of oncogenic human papillomavirus (HPV) infection: effect of smoking (United States) publication-title: Cancer Causes Control doi: 10.1023/A:1020668232219 – volume: 43 start-page: 5526 year: 2005 ident: 2022060919565960600_bib10 article-title: Analysis of the effect of DNA purification on detection of human papillomavirus in oral rinse samples by PCR publication-title: J Clin Microbiol doi: 10.1128/JCM.43.11.5526-5535.2005 |
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| Snippet | Background: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.... Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men. Oral... Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.BACKGROUNDOral... BACKGROUND: Oral human papillomavirus type-16 (HPV16) infection is a risk factor for oropharyngeal cancer. We examined oral HPV infection among healthy men.... |
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| SubjectTerms | Adolescent Adult Age Aged Anogenital Bioindicators Biological and medical sciences biomarkers Brazil - epidemiology Cancer Carcinogenicity Cohort Studies Data processing DNA Epidemiology Human papillomavirus Human papillomavirus 16 Human papillomavirus 16 - isolation & purification Humans Infection Inventories Male males Medical sciences Mexico - epidemiology Middle Aged Mouth - virology Mouth Diseases - epidemiology Mouth Diseases - virology oropharyngeal cancer Oropharyngeal Neoplasms - epidemiology Oropharyngeal Neoplasms - virology Papillomavirus Infections - epidemiology Papillomavirus Infections - virology Prevalence Risk Factors Sexual behavior Smoking - epidemiology Tobacco Tumors United States - epidemiology Young Adult |
| Title | The Epidemiology of Oral HPV Infection among a Multinational Sample of Healthy Men |
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