Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity - Sangaletti, Sabina; Tripodo, Claudio; Chiodoni, Claudia; Guarnotta, Carla; Cappetti, Barbara; Casalini, Patrizia; Piconese, Silvia; Parenza, Mariella; Guiducci, Cristiana; Vitali, Caterina; Colombo, Mario P. (Blood, 2012)
Keywords: Animals; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - etiology; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - pathology; Antibodies, Antineutrophil Cytoplasmic - blood; Antibodies, Antineutrophil Cytoplasmic - immunology; Apoptosis; Autoantigens; Autoimmunity - immunology; Biological and medical sciences; Blotting, Western; Cell Differentiation; Cell Proliferation; Cytosol - immunology; Cytosol - metabolism; Dendritic Cells - immunology; Dendritic Cells - metabolism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Hematologic and hematopoietic diseases; Humans; Immunization; Immunoenzyme Techniques; Medical sciences; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells - immunology; Myeloid Cells - metabolism; Neutrophils - immunology; Neutrophils - metabolism; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Skin - immunology; Skin - metabolism; Skin - pathology; Antigen; Autoimmunity; Dendritic cell; Antineutrophil cytoplasmic antibody; Hematology; Antigen presenting cell; Granulocyte; Myeloid dendritic cell; Neutrophil; Extracellular; Cytoplasm