Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-γ producing T-cells - Badell, Edgar; Nicolle, Fabienne; Clark, Simon; Majlessi, Laleh; Boudou, Frédéric; Martino, Angelo; Castello-Branco, Luiz; Leclerc, Claude; Lewis, David J.M.; Marsh, Philip D.; Gicquel, Brigitte; Winter, Nathalie (Vaccine, 2009)
Keywords: Acyltransferases - immunology; Administration, Intranasal; Allergy and Immunology; Animals; Antigens, Bacterial - immunology; Applied microbiology; Bacterial diseases; Bacterial Proteins - immunology; Bacteriology; BCG Vaccine - administration & dosage; BCG Vaccine - chemistry; BCG Vaccine - immunology; Biological and medical sciences; Female; Fundamental and applied biological sciences. Psychology; Guinea Pigs; Human bacterial diseases; Humans; IFNγ; Immunization, Secondary; Infectious diseases; Interferon-gamma - immunology; Life Sciences; Medical sciences; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbiology; Miscellaneous; Mucosa; Mycobacterium bovis - immunology; Mycobacterium tuberculosis - immunology; Mycobacterium tuberculosis - metabolism; T-Lymphocytes - immunology; Tuberculosis - immunology; Tuberculosis - prevention & control; Tuberculosis and atypical mycobacterial infections; Tuberculosis vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); IFNγ; Tuberculosis vaccines; Mucosa; Mycobacterium bovis; Cytokine; BCG; Vaccine; Intranasal administration; Mycobacterial infection; Subunit; Infection; Tuberculosis; Mycobacteriales; T-Lymphocyte; Bacteriosis; Mycobacteriaceae; Bacteria; Actinomycetes; Gamma interferon; MUCOSA; TUBERCULOSIS VACCINES; IFN GAMMA