Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors - Cheng, Shi-Bin; Nakashima, Akitoshi; Huber, Warren J.; Davis, Sarah; Banerjee, Sayani; Huang, Zheping; Saito, Shigeru; Sadovsky, Yoel; Sharma, Surendra (Cell death & disease, 2019)
Keywords: 13; 13/106; 13/51; 14; 14/19; 631/80/304; 692/420/256/2177; 82; 82/1; 82/29; 96; 96/1; 96/95; Adult; Antibodies; Autophagy; Biochemistry; Biomedical and Life Sciences; Carrier Proteins - genetics; Caspase-1; Cell Biology; Cell Culture; Cell death; Cell Hypoxia - genetics; Endoplasmic reticulum; Endoplasmic Reticulum Stress - genetics; Female; Humans; Hypoxia; IL-1β; Immunology; Inflammasomes; Inflammation; Inflammation - genetics; Inflammation - metabolism; Inflammation - pathology; Interleukin 18; Intracellular Signaling Peptides and Proteins - genetics; Life Sciences; Mimicry; Necroptosis; NLR Family, Pyrin Domain-Containing 3 Protein - genetics; Phagocytosis; Phosphate-Binding Proteins - genetics; Placenta; Placenta - metabolism; Placenta - pathology; Pre-eclampsia; Pre-Eclampsia - genetics; Pre-Eclampsia - metabolism; Pre-Eclampsia - pathology; Preeclampsia; Pregnancy; Protein folding; Pyrin protein; Pyroptosis; Pyroptosis - genetics; Signal Transduction; Thioredoxin; Trophoblasts; Trophoblasts - metabolism; Trophoblasts - pathology; Unfolded Protein Response - genetics