The newly emerged SARS-Like coronavirus HCoV-EMC also has an “Achilles’ heel”: current effective inhibitor targeting a 3C-like protease - Ren, Zhilin; Yan, Liming; Zhang, Ning; Guo, Yu; Yang, Cheng; Lou, Zhiyong; Rao, Zihe (Protein & cell, 2013)
Keywords: Binding Sites; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cysteine Endopeptidases - metabolism; Developmental Biology; Human Genetics; Humans; Isoxazoles - chemistry; Isoxazoles - pharmacology; Life Sciences; Perspective; Protease Inhibitors - chemistry; Protease Inhibitors - metabolism; Protease Inhibitors - pharmacology; Protein Science; Protein Structure, Tertiary; Pyrrolidinones - chemistry; Pyrrolidinones - pharmacology; Rhinovirus - drug effects; SARS Virus - drug effects; SARS Virus - enzymology; Severe Acute Respiratory Syndrome - virology; Stem Cells; Viral Proteins - antagonists & inhibitors; Viral Proteins - metabolism; Severe Acute Respiratory Syndrome; Substrate Binding Site; Colored Stick; Main Protease; Severe Acute Respiratory Syndrome Virus