Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects - Rajendran, Sharmalar; Willoughby, Scott R.; Chan, Wai Ping A.; Liberts, Elizabeth A.; Heresztyn, Tamila; Saha, Mrinal; Marber, Michael S.; Norman, Robert J.; Horowitz, John D. (Atherosclerosis, 2009)
Keywords: Adenosine Diphosphate; Adult; Albuterol - pharmacology; Arginine - analogs & derivatives; Arginine - blood; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Blood coagulation. Blood cells; Body Composition; C-Reactive Protein - metabolism; Cardiology. Vascular system; Cardiovascular; Cohort Studies; Endothelial Cells - pathology; Endothelial function; Endothelium, Vascular - drug effects; Endothelium, Vascular - metabolism; Endothelium, Vascular - pathology; Endothelium, Vascular - physiopathology; Female; Fundamental and applied biological sciences. Psychology; Humans; Inflammation Mediators - blood; Malondialdehyde - blood; Medical sciences; Molecular and cellular biology; Nitric oxide; Nitric Oxide - blood; Nitric Oxide Donors - pharmacology; Nitroglycerin - pharmacology; Nitroprusside - pharmacology; Obesity - blood; Obesity - complications; Obesity - physiopathology; Oxidative Stress; Platelet; Platelet Aggregation - drug effects; Platelet Function Tests; Platelets; Polycystic ovary syndrome; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - physiopathology; Stem Cells - pathology; Time Factors; Vasodilator Agents - pharmacology; Polycystic ovary syndrome; Endothelial function; Platelets; Nitric oxide; Human; Obesity; Nutrition disorder; Female sterility; Cardiovascular disease; Polycystic ovary; Female genital diseases; Thrombocytopathy; Vascular disease; Ovarian diseases; Platelet; Cyst; Atherosclerosis; Endothelial dysfunction; Benign neoplasm; Nutritional status