Daurichromenic Acid from the Chinese Traditional Medicinal Plant Rhododendron dauricum Inhibits Sphingomyelin Synthase and Aβ Aggregation - Deepak, Hadya Virupaksha; Swamy, Mahadeva M. M.; Murai, Yuta; Suga, Yoshiko; Anetai, Masaki; Yo, Takuro; Kuragano, Masahiro; Uwai, Koji; Tokuraku, Kiyotaka; Monde, Kenji (Molecules, 2020)
Keywords: Acids; Amyloid beta-Peptides - antagonists & inhibitors; Amyloid beta-Peptides - metabolism; amyloid β; Apoptosis; Cell growth; Chromans - chemistry; Chromans - pharmacology; daurichromenic acid; Disease; Dose-Response Relationship, Drug; Drugs, Chinese Herbal - chemistry; Drugs, Chinese Herbal - pharmacology; dual inhibitor; Enzyme Activation - drug effects; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Enzymes; Gram-positive bacteria; Herbal medicine; Ligands; lipid-related disease; Molecular Structure; Natural products; NMR; Nuclear magnetic resonance; Plants, Medicinal - chemistry; Protein Aggregates - drug effects; Quantum dots; Rhododendron - chemistry; sphingomyelin synthase; Staphylococcus infections; Traditional Chinese medicine; Transferases (Other Substituted Phosphate Groups) - antagonists & inhibitors; sphingomyelin synthase; daurichromenic acid; dual inhibitor; amyloid β; lipid-related disease