Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency - Mazerolles, Fabienne; Picard, Capucine; Kracker, Sven; Fischer, Alain; Durandy, Anne (Journal of allergy and clinical immunology, 2013)
Keywords: Adolescent; Adult; Allergy and Immunology; antibodies; antibody formation; Antigens; B-lymphocytes; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; B-Lymphocytes - pathology; Biological and medical sciences; Blood; CD4-positive T-lymphocytes; cell activation; Cell Differentiation; chemokine CXCL13; Child; CXCR5 receptor; Cytokines; Female; functional properties; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene Expression; heterozygosity; Heterozygote; Human; Humans; Immune system; immunoglobulin A; Immunoglobulin A - biosynthesis; Immunoglobulin A - immunology; immunoglobulin G; Immunoglobulin G - biosynthesis; Immunoglobulin G - immunology; Immunoglobulins; Immunopathology; Interleukins - biosynthesis; Interleukins - immunology; Job Syndrome - genetics; Job Syndrome - immunology; Job Syndrome - metabolism; Job Syndrome - pathology; Leukocyte Common Antigens - genetics; Leukocyte Common Antigens - immunology; Ligands; lymph nodes; Lymphocyte Activation; Lymphocyte Count; Lymphocytes; Male; Medical sciences; Middle Aged; Mutation; naive B cells; patients; Receptors, CXCR5 - genetics; Receptors, CXCR5 - immunology; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; signal transducer and activator of transcription 3 deficiency; Signal Transduction; STAT3 Transcription Factor - deficiency; STAT3 Transcription Factor - genetics; STAT3 Transcription Factor - immunology; T cells; T-Lymphocyte Subsets - immunology; T-Lymphocyte Subsets - metabolism; T-Lymphocyte Subsets - pathology; transcription (genetics); transcription factors; France; Human; CD40L; CD62L; signal transducer and activator of transcription 3 deficiency; CSR; cell activation; STAT3; ICOSL; T cells; SEB; Bcl6; TFH; naive B cells; GC; ICOS; IL-21R; PD-1; Inducible costimulator ligand; Programmed death 1; Germinal center; Signal transducer and activator of transcription 3; L-selectin; B-cell lymphoma 6; IL-21 receptor; Inducible costimulator; T FH; Class-switch recombination; CD40 ligand; Follicular T H