Critical role of RAGE and HMGB1 in inflammatory heart disease - Bangert, Anna; Andrassy, Martin; Müller, Anna-Maria; Bockstahler, Mariella; Fischer, Andrea; Volz, Christian H.; Leib, Christoph; Göser, Stefan; Korkmaz-Icöz, Sevil; Zittrich, Stefan; Jungmann, Andreas; Lasitschka, Felix; et al. (Proceedings of the National Academy of Sciences - PNAS, 2016)
Keywords: Animals; Autoimmune Diseases - metabolism; Autoimmune Diseases - pathology; Biological Sciences; Biopsy; Cardiomyopathy; Cardiovascular diseases; Dependovirus - metabolism; Down-Regulation - drug effects; Fibrosis; Freund's Adjuvant - immunology; Heart Diseases - blood; Heart Diseases - complications; Heart Diseases - genetics; Heart Diseases - pathology; Heart Function Tests; HMGB1 Protein - blood; HMGB1 Protein - metabolism; Immunization; Immunologic Factors - pharmacology; Inflammation - blood; Inflammation - complications; Inflammation - genetics; Inflammation - pathology; Inflammation Mediators - metabolism; Matrix Metalloproteinases - metabolism; Mice, Knockout; Myocarditis - complications; Myocarditis - genetics; Myocarditis - pathology; Myocarditis - physiopathology; Myocardium - metabolism; Myocardium - pathology; NF-kappa B - metabolism; Pathogenesis; PNAS Plus; Protein Binding - drug effects; Protein expression; Receptor for Advanced Glycation End Products - blood; Receptor for Advanced Glycation End Products - metabolism; Rodents; Signal Transduction - drug effects; Toll-Like Receptors - metabolism; Transcription, Genetic - drug effects; Troponin - metabolism; Up-Regulation - drug effects; Viruses; AAV; myocarditis; cytokines