Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump - Kirshenbaum, Greer S; Clapcote, Steven J; Duffy, Steven; Burgess, Christian R; Petersen, Janne; Jarowek, Karolina J; Yücel, Yeni H; Cortez, Miguel A; Snead, O. Carter III; Vilsen, Bente; Peever, John H; Ralph, Martin R; et al. (Proceedings of the National Academy of Sciences - PNAS, 2011)
Keywords: Animal models; Animals; Behavioral neuroscience; Biological Sciences; Bipolar disorder; Bipolar Disorder - genetics; Bipolar Disorder - physiopathology; Brain; Calcium Signaling; Cells, Cultured; Circadian Rhythm; etiology; gene expression; hippocampus; Lithium; Medical genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; mitogen-activated protein kinase; Motivation; mutation; Neurons; pathophysiology; patients; phenotype; Protein isoforms; Reward; Signal Transduction; Sodium; sodium-potassium-exchanging ATPase; Sodium-Potassium-Exchanging ATPase - genetics; Sodium-Potassium-Exchanging ATPase - physiology; Up-Regulation; valproic acid; Vehicles