The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline

A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings. Electrocardiograms over several years featured the Type 1 Brugada pattern. Careful electrocardiogram monitoring shou...

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Bibliographic Details
Published inJACC. Case reports Vol. 3; no. 1; pp. 156 - 161
Main Authors Chow, Ji-Jian, Kaza, Nandita, Varnava, Amanda
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.01.2021
Elsevier
Subjects
anorexia nervosa
antidepressive agents
Brugada syndrome
Cardiovascular
implantable cardioverter defibrillator
Mini-Focus Issue: Electrophysiology
risk stratification
tricyclic
ventricular tachycardia
antidepressive agents
implantable cardioverter defibrillator
BrS
risk stratification
TCA
Brugada syndrome
ventricular tachycardia
ECG
tricyclic
ICD
anorexia nervosa
VT
electrocardiogram
tricyclic antidepressant
implantable cardioverter-defibrillator
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ISSN2666-0849
2666-0849
DOI10.1016/j.jaccas.2020.11.016

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Summary:A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings. Electrocardiograms over several years featured the Type 1 Brugada pattern. Careful electrocardiogram monitoring should be made if using high doses of amitriptyline, especially in those with low body weight. (Level of Difficulty: Intermediate.) [Display omitted]
Bibliography:ObjectType-Case Study-2
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Drs. Chow and Kaza are joint first authors on this paper.
ISSN:2666-0849
2666-0849
DOI:10.1016/j.jaccas.2020.11.016