Intraoperative radiotherapy for early breast cancer - insufficient evidence to change practice

We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IORT) in women with early stage breast cancer outside of a clinical trial, as the recently reported TARGIT-A trial does not provide sufficient evidence to conclude that IORT is superior to no radiotherapy.

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Bibliographic Details
Published inNature reviews. Clinical oncology Vol. 17; no. 12; pp. 723 - 724
Main Authors Sasieni, Peter D, Sawyer, Elinor J
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 01.12.2020
Subjects
Breast cancer
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
Humans
Mastectomy, Segmental
Neoplasm Recurrence, Local
Radiation therapy
Radiotherapy, Adjuvant
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ISSN1759-4774
1759-4782
DOI10.1038/s41571-020-00444-2

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Summary:We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IORT) in women with early stage breast cancer outside of a clinical trial, as the recently reported TARGIT-A trial does not provide sufficient evidence to conclude that IORT is superior to no radiotherapy.
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ISSN:1759-4774
1759-4782
DOI:10.1038/s41571-020-00444-2