Effects of the MEK inhibitor, SL-327, on rewarding, motor- and cellular-activating effects of d-amphetamine and SKF-82958, and their augmentation by food restriction in rat - Carr, Kenneth D.; de Vaca, Soledad Cabeza; Sun, Yanjie; Chau, Lily S.; Pan, Yan; Dela Cruz, Julie (Psychopharmacologia, 2009)
Keywords: Aminoacetonitrile - analogs & derivatives; Aminoacetonitrile - pharmacology; Animal behavior; Animal cognition; Animals; Benzazepines - pharmacology; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Dextroamphetamine - pharmacology; Food Deprivation; Injections, Intraperitoneal; Male; Medical sciences; Mitogen-Activated Protein Kinase 1 - drug effects; Mitogen-Activated Protein Kinase 1 - metabolism; Mitogen-Activated Protein Kinase 3 - drug effects; Mitogen-Activated Protein Kinase 3 - metabolism; Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors; Motor Activity - drug effects; Neuropharmacology; Neurosciences; Nucleus Accumbens - drug effects; Nucleus Accumbens - metabolism; Original Investigation; Pharmacology. Drug treatments; Pharmacology/Toxicology; Psychiatry; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease); Psychology. Psychoanalysis. Psychiatry; Psychopharmacology; Psychotropic drugs; Rats; Rats, Sprague-Dawley; Reward; Rodents; Signal Transduction - drug effects; SKF-82958; SL-327; c; amphetamine; ERK 1/2; Self-stimulation; Reward; Food restriction; U0126; Amphetamine derivatives; Food restriction . Reward; Extracellular signal-regulated protein kinase; Rat; Psychotropic; D-amphetamine; Protooncogene; CNS stimulant; Enzyme; Transferases; fos Gene; Rodentia; Mitogen-activated protein kinase; In vitro; Feeding; Vertebrata; Mammalia; Animal; C-Onc gene; Self stimulation; Dexamfetamine; Inhibitor; c-fos . ERK 1/2 . SL-327 . U0126; Restricted diet; Immediate early gene