Frataxin mRNA Isoforms in FRDA Patients and Normal Subjects: Effect of Tocotrienol Supplementation - Casadio, Rita; Tasco, Gianluca; Ghezzo, Alessandro; Manfredini, Stefano; Malisardi, Gemma; Bolotta, Alessandra; Marini, Marina; Abruzzo, Provvidenza Maria; Pini, Antonella (BioMed research international, 2013)
Keywords: Alternative splicing; Amino Acid Sequence; Ataxia; Biomedical research; Carbon-Sulfur Lyases - metabolism; Case-Control Studies; Cell culture; Dietary Supplements; DNA, Complementary - genetics; Frataxin; Friedreich Ataxia - drug therapy; Friedreich Ataxia - genetics; Friedreich's ataxia; Gene expression; Gene Expression Regulation - drug effects; Genetic aspects; Humans; Identification and classification; Iron-Binding Proteins - chemistry; Iron-Binding Proteins - genetics; Iron-Binding Proteins - metabolism; Messenger RNA; Molecular Docking Simulation; Molecular Sequence Data; Oxidative stress; PPAR gamma - genetics; PPAR gamma - metabolism; Properties; Protein Binding - drug effects; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Isoforms - genetics; RNA Isoforms - metabolism; Studies; Tocotrienols; Tocotrienols - pharmacology; Tocotrienols - therapeutic use