Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers - Maltais, Loïka; Montagne, Martin; Bédard, Mikaël; Tremblay, Cynthia; Soucek, Laura; Lavigne, Pierre (PloS one, 2017)
Keywords: Affinity; Alternative Splicing; Amino Acid Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism; Binding; Biology and life sciences; Cancer; Cell growth; Deoxyribonucleic acid; Dimerization; DNA; DNA - chemistry; DNA - metabolism; E-Box Elements; Gene expression; Gene sequencing; Humans; Leucine; Medicine and Health Sciences; Models, Molecular; Mutation; Neoplasms - genetics; Neoplasms - metabolism; Oncogenes; Physical sciences; Physiology; Protein Multimerization; Proteins; Proto-Oncogene Proteins c-myc - metabolism; Repressor Proteins - chemistry; Repressor Proteins - genetics; Repressor Proteins - metabolism; Research and analysis methods; Transcription factors; Tumor Suppressor Proteins - chemistry; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism; Tumors; Canada; Spain