Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance - Matthews, V. B; Allen, T. L; Risis, S; Chan, M. H. S; Henstridge, D. C; Watson, N; Zaffino, L. A; Babb, J. R; Boon, J; Meikle, P. J; Jowett, J. B; Watt, M. J; et al. (Diabetologia, 2010)
Keywords: Adipocytes; Adipocytes - metabolism; Adipocytes - pathology; Adiposity; Adiposity - genetics; Animals; Biological and medical sciences; Body Composition; Body Composition - genetics; Body fat; Calorimetry, Indirect; Cell Size; Cytokines; deficiency; Dehydrogenases; Diabetes; Diabetes. Impaired glucose tolerance; Diet; Diglycerides; Diglycerides - metabolism; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fatty liver; Fatty Liver - genetics; Fatty Liver - metabolism; Female; Gastroenterology. Liver. Pancreas. Abdomen; genetics; Glucose; Human Physiology; immunology; Inflammation; Inflammation - genetics; Insulin Resistance; Insulin Resistance - genetics; Interleukin-6; Interleukin-6 - deficiency; Interleukin-6 - genetics; Internal Medicine; Kinases; Lipids; Liver; Liver - immunology; Liver - metabolism; Liver - pathology; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical and Health Sciences; Medical research; Medical sciences; Medicin och hälsovetenskap; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Musculoskeletal system; noninsulin-dependent diabetes mellitus; Obesity; Obesity - genetics; Obesity - metabolism; Other diseases. Semiology; pathology; Physiology; Proteins; Signal transduction; Triglycerides; Triglycerides - metabolism; Type 2 diabetes; Australia; United States--US; Type 2 diabetes; Obesity; Signal transduction; Fatty liver; Cytokines; Endocrinopathy; Rodentia; Nutrition disorder; Cytokine; Metabolic diseases; Hepatic disease; Inflammation; Interleukin 6; Target tissue resistance; Vertebrata; Mammalia; Mouse; Animal; Digestive diseases; Insulin resistance; Nutritional status