Association of loneliness with all-cause mortality: A meta-analysis
Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characte...
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| Published in | PloS one Vol. 13; no. 1; p. e0190033 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Public Library of Science
01.01.2018
Public Library of Science (PLoS) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1932-6203 1932-6203 |
| DOI | 10.1371/journal.pone.0190033 |
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| Abstract | Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.
Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.
A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.
Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. |
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| AbstractList | Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.INTRODUCTIONLoneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.METHODSPubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.RESULTSA total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression.CONCLUSIONSLoneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model. A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately. Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. Introduction Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. Methods Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model. Results A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately. Conclusions Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. Introduction Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. Methods Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model. Results A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately. Conclusions Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published articles that measured loneliness and mortality. The main characteristics and the effect size values of each article were extracted. Moreover, an evaluation of the quality of the articles included was also carried out. A meta-analysis was performed firstly with all the included articles and secondly separating by gender, using a random effects model.A total of 35 articles involving 77220 participants were included in the systematic review. Loneliness is a risk factor for all-cause mortality [pooled HR = 1.22, 95% CI = (1.10, 1.35), p < 0.001] for both genders together, and for women [pooled HR = 1.26, 95% CI = (1.07, 1.48); p = 0.005] and men [pooled HR = 1.44; 95% CI = (1.19, 1.76); p < 0.001] separately.Loneliness shows a harmful effect for all-cause mortality and this effect is slightly stronger in men than in women. Moreover, the impact of loneliness was independent from the quality evaluation of each article and the effect of depression. |
| Author | Cabello, María Miret, Marta Rico-Uribe, Laura Alejandra Martín-María, Natalia Caballero, Francisco Félix Ayuso-Mateos, José Luis |
| AuthorAffiliation | 1 Department of Psychiatry, Universidad Autónoma de Madrid, Madrid, Spain Jerusalem Institute of Aging Research, ISRAEL 2 Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain 3 Department of Psychiatry, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Madrid, Spain |
| AuthorAffiliation_xml | – name: 1 Department of Psychiatry, Universidad Autónoma de Madrid, Madrid, Spain – name: Jerusalem Institute of Aging Research, ISRAEL – name: 2 Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain – name: 3 Department of Psychiatry, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Madrid, Spain |
| Author_xml | – sequence: 1 givenname: Laura Alejandra surname: Rico-Uribe fullname: Rico-Uribe, Laura Alejandra – sequence: 2 givenname: Francisco Félix surname: Caballero fullname: Caballero, Francisco Félix – sequence: 3 givenname: Natalia surname: Martín-María fullname: Martín-María, Natalia – sequence: 4 givenname: María surname: Cabello fullname: Cabello, María – sequence: 5 givenname: José Luis surname: Ayuso-Mateos fullname: Ayuso-Mateos, José Luis – sequence: 6 givenname: Marta orcidid: 0000-0003-3252-854X surname: Miret fullname: Miret, Marta |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29300743$$D View this record in MEDLINE/PubMed |
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| Snippet | Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.
Pubmed, PsycINFO,... Introduction Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.... Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause... Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.Pubmed, PsycINFO,... Introduction Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality.... |
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| SubjectTerms | Biology and Life Sciences Evaluation Loneliness Medical ethics Medicine and Health Sciences Mental depression Meta-analysis Mortality Older people People and places Physical Sciences Quality assessment Research and Analysis Methods Risk factors Science Policy Social networks Social support |
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| Title | Association of loneliness with all-cause mortality: A meta-analysis |
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