Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation - Kang, Jeong-Gu; Majerciak, Vladimir; Uldrick, Thomas S; Wang, Xiaohong; Kruhlak, Michael; Yarchoan, Robert; Zheng, Zhi-Ming (The Journal of pathology, 2011)
Keywords: Base Sequence; Binding Sites - genetics; Biological and medical sciences; Castleman's disease; Conserved Sequence; Dermatology; gene expression; Gene Expression Regulation - genetics; Gene Expression Regulation, Viral - genetics; Germinal Center - metabolism; Germinal centers; germinal centre; HEK293 Cells; HeLa Cells; Herpesviridae Infections - genetics; Herpesviridae Infections - metabolism; Herpesvirus 8, Human - genetics; Herpesvirus 8, Human - metabolism; Human herpesvirus 8; Humans; IL-6; Infectious diseases; Interleukin 6; Interleukin-6 - biosynthesis; Interleukin-6 - genetics; Investigative techniques, diagnostic techniques (general aspects); Kaposi's sarcoma-associated herpesvirus; Lymph nodes; Lymph Nodes - metabolism; Medical sciences; MicroRNAs - genetics; miRNA; Molecular Sequence Data; Open reading frames; Open Reading Frames - genetics; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Point mutation; post-transcriptional regulation; RNA, Viral - genetics; Seeds; Transfection; Tumors; Tumors of the skin and soft tissue. Premalignant lesions; Viral diseases; viral IL-6; Viral Proteins - biosynthesis; Viral Proteins - genetics; Skin disease; RNA interference; Transcription; post-transcriptional regulation; Binding site; Interleukin 6; Kaposi sarcoma; Human herpesvirus 8; Regulation(control); miRNA; Cell; Gammaherpesvirinae; Human; Herpesviridae; Cytokine; Micro RNA; Malignant tumor; Gene expression; IL-6; Open reading frame; Infection; Virus; Gene silencing; Anatomic pathology; Kaposi's sarcoma-associated herpesvirus; germinal centre; Viral disease; viral IL-6; Cancer