Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma - Bosse, Kristopher R.; Raman, Pichai; Zhu, Zhongyu; Lane, Maria; Martinez, Daniel; Heitzeneder, Sabine; Rathi, Komal S.; Kendsersky, Nathan M.; Randall, Michael; Donovan, Laura; Morrissy, Sorana; Sussman, Robyn T.; et al. (Cancer cell, 2017)
Keywords: Animals; Antibodies, Neoplasm - metabolism; antibody-drug conjugate; Cell Death; Cell Line, Tumor; Cell Membrane - metabolism; Cell Proliferation; Child; Gene Expression Regulation, Neoplastic; Genome, Human; glypican; Glypicans - metabolism; Humans; Immunotherapy; medulloblastoma; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; MYCN; N-Myc Proto-Oncogene Protein - metabolism; neuroblastoma; Neuroblastoma - genetics; Neuroblastoma - immunology; Neuroblastoma - pathology; Neuroblastoma - therapy; Oncogene Proteins - metabolism; Risk Factors; RNA, Messenger - genetics; RNA, Messenger - metabolism; neuroblastoma; MYCN; antibody-drug conjugate; glypican; medulloblastoma; immunotherapy