Bayesian population approaches to the analysis of dose escalation studies - Russu, Alberto; Nicolao, Giuseppe De; Poggesi, Italo; Neve, Marta; Gomeni, Roberto (Computer methods and programs in biomedicine, 2012)
Keywords: Bayes Theorem; Bayesian population model; Biological and medical sciences; Clinical Trials, Phase I as Topic - methods; Clinical Trials, Phase I as Topic - statistics & numerical data; Computer Simulation; Dose escalation; Dose-Response Relationship, Drug; Endpoint Determination - methods; Humans; Internal Medicine; Likelihood Functions; Medical sciences; Mixed effects model; Models, Biological; Models, Statistical; Other; Pharmaceutical Preparations - blood; Pharmacokinetics; Phase I trials; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Technology. Biomaterials. Equipments. Material. Instrumentation; Mixed effects model; Dose escalation; Phase I trials; Bayesian population model; Biomedical engineering