Anti-diabetic activity of embelin: Involvement of cellular inflammatory mediators, oxidative stress and other biomarkers - Naik, Suresh R.; Niture, Netaji T.; Ansari, Ansar A.; Shah, Priyank D. (Phytomedicine (Stuttgart), 2013)
Keywords: adjuvants; animal disease models; Animals; Anti-hyperglycemic activity; Antioxidants; benzoquinones; Benzoquinones - isolation & purification; Benzoquinones - pharmacology; Benzoquinones - therapeutic use; biomarkers; Biomarkers - blood; blood glucose; body weight; catalase; Corticosteroids; Diabetes Mellitus, Experimental - drug therapy; Diabetes Mellitus, Experimental - pathology; Diabetes therapy; Dosage and administration; Drug interactions; Embelia; Embelia - chemistry; Embelin; Female; fruit extracts; glutathione; glycemic effect; glycosylation; hemoglobin; hepatocytes; high fat diet; High fat diet + streptozotocin diabetes; humans; hypoglycemic agents; Hypoglycemic Agents - pharmacology; Hypoglycemic Agents - therapeutic use; Inflammation Mediators - physiology; interleukin-6; Lipid profile; lipids; liver; Male; malondialdehyde; medicinal properties; noninsulin-dependent diabetes mellitus; oxidative stress; Oxidative Stress - drug effects; pancreas; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Pro-inflammatory cytokines; Random Allocation; Rats; Rats, Sprague-Dawley; superoxide dismutase; tumor necrosis factors; India; Antioxidants; Pro-inflammatory cytokines; Lipid profile; Embelin; Anti-hyperglycemic activity; High fat diet+streptozotocin diabetes