Protective effects of paeoniflorin and albiflorin on chemotherapy-induced myelosuppression in mice - ZHU, Ying-Li; WANG, Lin-Yuan; WANG, Jing-Xia; WANG, Chun; WANG, Cheng-Long; ZHAO, Dan-Ping; WANG, Zi-Chen; ZHANG, Jian-Jun (Chinese journal of natural medicines, 2016)
Keywords: Albiflorin; Animals; Antineoplastic Agents - adverse effects; atrophy; blood cell counts; blood serum; bone marrow; bone marrow cells; Bridged-Ring Compounds - administration & dosage; Chemotherapy; cyclophosphamide; Cyclophosphamide - adverse effects; drug therapy; Drugs, Chinese Herbal - administration & dosage; enzyme-linked immunosorbent assay; gene expression; Glucosides - administration & dosage; granulocyte colony-stimulating factor; Granulocyte Colony-Stimulating Factor - genetics; Granulocyte Colony-Stimulating Factor - metabolism; granulocyte-macrophage colony-stimulating factor; Granulocyte-Macrophage Colony-Stimulating Factor - genetics; Granulocyte-Macrophage Colony-Stimulating Factor - metabolism; Hematologic Diseases - etiology; Hematologic Diseases - genetics; Hematologic Diseases - metabolism; Hematologic Diseases - prevention & control; histology; Humans; interleukin-3; Interleukin-3 - genetics; Interleukin-3 - metabolism; interleukin-6; Interleukin-6 - metabolism; isomers; leukocytes; Male; messenger RNA; Mice; Monoterpenes - administration & dosage; Myelosuppression; Oriental traditional medicine; Paeonia; Paeonia - chemistry; Paeonia lactiflora; Paeoniflorin; protective effect; protein content; radioimmunoassays; spleen; thymus gland; tumor necrosis factor-alpha; Tumor Necrosis Factor-alpha - genetics; Tumor Necrosis Factor-alpha - metabolism; Paeoniflorin; Myelosuppression; Chemotherapy; Albiflorin