Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries - Owen, Katherine A.; Price, Andrew; Ainsworth, Hannah; Aidukaitis, Bryce N.; Bachali, Prathyusha; Catalina, Michelle D.; Dittman, James M.; Howard, Timothy D.; Kingsmore, Kathryn M.; Labonte, Adam C.; Marion, Miranda C.; Robl, Robert D.; et al. (American journal of human genetics, 2020)
Keywords: ancesty; B-Lymphocytes - immunology; B-Lymphocytes - pathology; Black People; Bortezomib - therapeutic use; DNA, Intergenic - genetics; DNA, Intergenic - immunology; drug repurposing; Enhancer Elements, Genetic; Gene Expression; Gene Ontology; Gene Regulatory Networks; Genetic Predisposition to Disease; genetics; Genome, Human; Genome-Wide Association Study; GWAS; Heterocyclic Compounds - therapeutic use; Humans; Immunochip; Interferons - genetics; Interferons - immunology; Isoquinolines - therapeutic use; Lactams; lupus; Lupus Erythematosus, Systemic - drug therapy; Lupus Erythematosus, Systemic - ethnology; Lupus Erythematosus, Systemic - genetics; Lupus Erythematosus, Systemic - immunology; Molecular Sequence Annotation; pathway analysis; Polymorphism, Single Nucleotide; Protein Array Analysis; Quantitative Trait Loci; Quantitative Trait, Heritable; SLE; White People; drug repurposing; genetics; GWAS; Immunochip; pathway analysis; SLE; ancesty; lupus