Imaging Large-Scale Neural Activity with Cellular Resolution in Awake, Mobile Mice

We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with i...

Full description

Saved in:

Bibliographic Details
Published in	Neuron (Cambridge, Mass.) Vol. 56; no. 1; pp. 43 - 57
Main Authors	Dombeck, Daniel A., Khabbaz, Anton N., Collman, Forrest, Adelman, Thomas L., Tank, David W.
Format	Journal Article
Language	English
Published	United States Elsevier Inc 04.10.2007 Elsevier Limited
Subjects	Algorithms Animals Astrocytes - physiology Behavior, Animal Brain - cytology Diagnostic Imaging - instrumentation Diagnostic Imaging - methods Equipment Design Exercise Test - methods Female Fitness equipment Luminescent Proteins - metabolism Male Markov Chains Mice Mice, Transgenic Models, Neurological Motor Activity - physiology Neurons Neurons - physiology Organic Chemicals - metabolism SYSNEURO Wakefulness - physiology Walking SYSNEURO
Online Access	Get full text
ISSN	0896-6273 1097-4199 1097-4199
DOI	10.1016/j.neuron.2007.08.003

Cover

Abstract	We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to ∼2-5 μm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%.
AbstractList	We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to approximately 2-5 microm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%.We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to approximately 2-5 microm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%. We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to ∼2-5 μm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%. We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to 2-5 is a subset of m. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%. We report a technique for two-photon fluorescence imaging with cellular resolution in awake behaving mice with minimal motion artifact. The apparatus combines an upright table mounted two-photon microscope with a spherical treadmill consisting of a large air supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball’s upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their head remains motionless. Image sequences demonstrate that running-associated brain motion is limited to ~2–5 µm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom designed Hidden Markov Model based motion correction algorithm useful for post-processing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion induced false positive error rate of <5%. We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to approximately 2-5 microm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%. We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines an upright, table-mounted two-photon microscope with a spherical treadmill consisting of a large, air-supported Styrofoam ball. Mice, with implanted cranial windows, are head restrained under the objective while their limbs rest on the ball's upper surface. Following adaptation to head restraint, mice maneuver on the spherical treadmill as their heads remain motionless. Image sequences demonstrate that running-associated brain motion is limited to ∼2-5 μm. In addition, motion is predominantly in the focal plane, with little out-of-plane motion, making the application of a custom-designed Hidden-Markov-Model-based motion correction algorithm useful for postprocessing. Behaviorally correlated calcium transients from large neuronal and astrocytic populations were routinely measured, with an estimated motion-induced false positive error rate of <5%.
Author	Dombeck, Daniel A. Tank, David W. Adelman, Thomas L. Khabbaz, Anton N. Collman, Forrest
Author_xml	– sequence: 1 givenname: Daniel A. surname: Dombeck fullname: Dombeck, Daniel A. organization: Department of Molecular Biology, Carl Icahn Labs, Princeton University, Princeton, NJ 08544, USA – sequence: 2 givenname: Anton N. surname: Khabbaz fullname: Khabbaz, Anton N. organization: Department of Molecular Biology, Carl Icahn Labs, Princeton University, Princeton, NJ 08544, USA – sequence: 3 givenname: Forrest surname: Collman fullname: Collman, Forrest organization: Department of Molecular Biology, Carl Icahn Labs, Princeton University, Princeton, NJ 08544, USA – sequence: 4 givenname: Thomas L. surname: Adelman fullname: Adelman, Thomas L. organization: Department of Molecular Biology, Carl Icahn Labs, Princeton University, Princeton, NJ 08544, USA – sequence: 5 givenname: David W. surname: Tank fullname: Tank, David W. email: dwtank@princeton.edu organization: Department of Molecular Biology, Carl Icahn Labs, Princeton University, Princeton, NJ 08544, USA
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/17920014$$D View this record in MEDLINE/PubMed
BookMark	eNqVkV-LEzEUxYOsuN3qNxAZEHxyxpvMJJPxQSjFXRe6Cqs-hzS9001Nk5qZaem3N7XFP_vgIgRCyDmHc3_3gpz54JGQ5xQKClS8WRUehxh8wQDqAmQBUD4iIwpNnVe0ac7ICGQjcsHq8pxcdN0KgFa8oU_IOa0bdniNyO31Wi-tX2YzHZeYfzbaYfYxBWuXTUxvt7bfZzvb32VTdG5wOma32AU39Db4zPpsstPf8HV2E-Y2OW-swafkcatdh89O95h8vXz_Zfohn326up5OZrnhDPpcSCpajrqiUhvGa8GxRoPUUMkNqzS0MpXktEE-N5IvGilYBaXRtDJt1czLMeHH3MFv9H6nnVObaNc67hUFdWCkVurISB0YKZAqMUq-d0ffZpivcWHQ92naX96grfr7x9s7tQxbxZiQkGiOyatTQAzfB-x6tbadSXi0xzB0SshSpOIPCxnUskonCV_eE67CEH2ipyiHshbAfqpe_Fn897SnbSbB26PAxNB1EVtlbK8Pm0pzWPcQluqe-f9oYlr11mJUnbHoDS5sRNOrRbD_DvgBRgDeBg
CitedBy_id	crossref_primary_10_1016_j_cell_2017_05_023 crossref_primary_10_1242_jcs_189001 crossref_primary_10_7554_eLife_51675 crossref_primary_10_1038_s41593_021_00943_0 crossref_primary_10_1016_j_biopsych_2020_02_008 crossref_primary_10_1038_s41593_024_01612_8 crossref_primary_10_1002_jemt_22342 crossref_primary_10_1371_journal_pbio_3001530 crossref_primary_10_1038_s41467_021_24211_8 crossref_primary_10_1523_JNEUROSCI_4400_10_2010 crossref_primary_10_1101_pdb_prot081778 crossref_primary_10_1109_TBCAS_2012_2218106 crossref_primary_10_1523_ENEURO_0143_19_2019 crossref_primary_10_1523_JNEUROSCI_2857_17_2018 crossref_primary_10_1038_s41467_022_28635_8 crossref_primary_10_1038_srep43388 crossref_primary_10_1016_j_expneurol_2012_07_014 crossref_primary_10_1038_nrn3962 crossref_primary_10_3389_fnsys_2016_00076 crossref_primary_10_1016_j_neuroscience_2024_10_035 crossref_primary_10_1111_j_1471_4159_2008_05830_x crossref_primary_10_1016_j_neuron_2008_09_004 crossref_primary_10_1126_science_aaf3319 crossref_primary_10_1523_ENEURO_0417_17_2018 crossref_primary_10_1016_j_neuron_2020_05_022 crossref_primary_10_1016_j_neulet_2019_02_034 crossref_primary_10_1016_j_neures_2011_06_011 crossref_primary_10_1152_jn_00697_2019 crossref_primary_10_1038_s41592_021_01329_7 crossref_primary_10_1016_j_neuron_2016_03_014 crossref_primary_10_1364_JOSAB_393128 crossref_primary_10_1109_TBME_2022_3229513 crossref_primary_10_1073_pnas_1209448109 crossref_primary_10_1038_s41586_019_1261_9 crossref_primary_10_1038_s41592_022_01422_5 crossref_primary_10_3389_fninf_2014_00080 crossref_primary_10_1371_journal_pone_0075678 crossref_primary_10_2139_ssrn_3316810 crossref_primary_10_1016_j_jneumeth_2013_10_004 crossref_primary_10_1016_j_neuron_2019_01_009 crossref_primary_10_2217_fnl_13_38 crossref_primary_10_1016_j_celrep_2020_01_105 crossref_primary_10_1016_j_neuron_2017_06_049 crossref_primary_10_1038_nprot_2014_165 crossref_primary_10_1146_annurev_neuro_051508_135540 crossref_primary_10_1016_j_neuron_2011_08_009 crossref_primary_10_1016_j_ceca_2021_102358 crossref_primary_10_1371_journal_pone_0031896 crossref_primary_10_1523_JNEUROSCI_0895_19_2019 crossref_primary_10_1152_jn_01310_2007 crossref_primary_10_1016_j_celrep_2017_10_013 crossref_primary_10_1038_nature18942 crossref_primary_10_1364_OL_412760 crossref_primary_10_1088_1741_2552_ad83c0 crossref_primary_10_1038_nature14103 crossref_primary_10_1038_srep12621 crossref_primary_10_1038_s41467_023_40044_z crossref_primary_10_1113_jphysiol_2008_167171 crossref_primary_10_1063_1_3081635 crossref_primary_10_1109_TBME_2015_2406113 crossref_primary_10_1016_j_ceca_2013_09_001 crossref_primary_10_1016_j_conb_2010_05_003 crossref_primary_10_1038_s41592_019_0663_9 crossref_primary_10_1016_j_neuron_2008_10_013 crossref_primary_10_1093_cercor_bhz083 crossref_primary_10_1002_dev_21305 crossref_primary_10_1038_s41467_018_04349_8 crossref_primary_10_1016_j_conb_2021_05_001 crossref_primary_10_1016_j_celrep_2018_05_062 crossref_primary_10_1016_j_pneurobio_2015_04_003 crossref_primary_10_1073_pnas_1210929109 crossref_primary_10_7554_eLife_85111 crossref_primary_10_1523_JNEUROSCI_0793_16_2016 crossref_primary_10_1016_j_neuron_2016_12_019 crossref_primary_10_7554_eLife_39777 crossref_primary_10_1038_nrn2864 crossref_primary_10_1016_j_neuron_2011_10_009 crossref_primary_10_1016_j_expneurol_2019_05_010 crossref_primary_10_2967_jnumed_112_109090 crossref_primary_10_1523_JNEUROSCI_1828_20_2021 crossref_primary_10_1016_j_neuron_2018_06_028 crossref_primary_10_1152_ajpcell_00416_2019 crossref_primary_10_1117_1_3505021 crossref_primary_10_1152_jn_00356_2012 crossref_primary_10_1364_BOE_6_000421 crossref_primary_10_1016_j_neuroscience_2016_09_035 crossref_primary_10_1117_1_NPh_1_1_011014 crossref_primary_10_1523_JNEUROSCI_5559_05_2008 crossref_primary_10_1016_j_bpj_2008_08_005 crossref_primary_10_3389_fncir_2017_00056 crossref_primary_10_1093_cercor_bhs122 crossref_primary_10_1093_function_zqad019 crossref_primary_10_1101_pdb_prot081737 crossref_primary_10_3389_fncir_2021_786293 crossref_primary_10_1016_j_neuron_2010_01_033 crossref_primary_10_1152_jn_00609_2011 crossref_primary_10_1038_s41598_019_43024_w crossref_primary_10_1038_nmeth_1468 crossref_primary_10_7554_eLife_37683 crossref_primary_10_1016_j_celrep_2020_02_043 crossref_primary_10_1016_j_conb_2013_11_002 crossref_primary_10_1021_acschemneuro_6b00307 crossref_primary_10_7554_eLife_86805_4 crossref_primary_10_1038_s41592_020_0851_7 crossref_primary_10_1021_nn401410k crossref_primary_10_1073_pnas_1901712116 crossref_primary_10_1038_nmeth_1582 crossref_primary_10_1016_j_neuron_2016_02_019 crossref_primary_10_1117_1_NPh_1_1_011008 crossref_primary_10_1016_j_jmp_2016_04_006 crossref_primary_10_7554_eLife_48571 crossref_primary_10_1038_s42003_023_04896_x crossref_primary_10_1038_nature10918 crossref_primary_10_1038_ncomms4262 crossref_primary_10_3389_fnins_2014_00211 crossref_primary_10_1016_j_neuron_2013_07_052 crossref_primary_10_1016_j_cell_2015_11_061 crossref_primary_10_1142_S0129065715500264 crossref_primary_10_1038_s41598_018_21640_2 crossref_primary_10_1523_JNEUROSCI_2925_19_2020 crossref_primary_10_1523_ENEURO_0023_21_2021 crossref_primary_10_1038_s41467_021_23829_y crossref_primary_10_1016_j_neuron_2018_06_002 crossref_primary_10_1038_s41586_023_06864_1 crossref_primary_10_1038_s41592_020_0961_2 crossref_primary_10_1016_j_ceca_2013_10_004 crossref_primary_10_1016_j_neuron_2020_04_013 crossref_primary_10_1364_BOE_434146 crossref_primary_10_1371_journal_pone_0019928 crossref_primary_10_1523_JNEUROSCI_5289_11_2011 crossref_primary_10_1002_jbio_202300214 crossref_primary_10_1016_j_neuron_2010_06_033 crossref_primary_10_3389_fncel_2024_1408607 crossref_primary_10_3390_ijms24086985 crossref_primary_10_3389_fnmol_2020_00030 crossref_primary_10_1038_s41467_023_36042_w crossref_primary_10_7554_eLife_89986 crossref_primary_10_1016_j_compmedimag_2011_08_002 crossref_primary_10_1515_revneuro_2022_0127 crossref_primary_10_1080_10888705_2021_1941023 crossref_primary_10_1364_BOE_394649 crossref_primary_10_1016_j_neuron_2022_10_037 crossref_primary_10_1038_ncomms15557 crossref_primary_10_1073_pnas_1109202108 crossref_primary_10_1126_science_aav5282 crossref_primary_10_1038_s41467_020_17005_x crossref_primary_10_1146_annurev_cellbio_100913_013053 crossref_primary_10_1016_j_neuron_2023_09_006 crossref_primary_10_1016_j_neuron_2023_11_019 crossref_primary_10_3389_fnins_2014_00118 crossref_primary_10_1117_1_3646209 crossref_primary_10_1016_j_cub_2019_07_037 crossref_primary_10_1016_j_neuron_2023_11_022 crossref_primary_10_1016_j_conb_2010_04_008 crossref_primary_10_1038_nmeth_1694 crossref_primary_10_1038_nmeth_1453 crossref_primary_10_3390_ma11081283 crossref_primary_10_1021_acs_nanolett_7b00956 crossref_primary_10_1142_S1793545819300027 crossref_primary_10_1038_s41593_025_01874_w crossref_primary_10_1016_j_bbamcr_2012_12_017 crossref_primary_10_1038_s41592_018_0234_5 crossref_primary_10_1117_1_NPh_11_4_045010 crossref_primary_10_1016_j_brainresrev_2009_11_007 crossref_primary_10_1016_j_nlm_2011_04_010 crossref_primary_10_1016_j_jneumeth_2010_10_007 crossref_primary_10_1146_annurev_neuro_061010_113813 crossref_primary_10_1523_JNEUROSCI_2601_12_2012 crossref_primary_10_1016_j_neuroscience_2021_10_022 crossref_primary_10_1364_BOE_6_004546 crossref_primary_10_1038_s41592_020_0759_2 crossref_primary_10_1167_jov_20_2_7 crossref_primary_10_1038_s43586_022_00147_1 crossref_primary_10_1186_s40708_022_00166_4 crossref_primary_10_1016_j_jneumeth_2008_08_020 crossref_primary_10_1146_annurev_bioeng_071813_104733 crossref_primary_10_1515_RNS_2011_052 crossref_primary_10_1113_jphysiol_2013_253138 crossref_primary_10_1515_RNS_2011_053 crossref_primary_10_1364_OME_9_003729 crossref_primary_10_3389_fnbeh_2016_00236 crossref_primary_10_1016_j_cub_2019_10_017 crossref_primary_10_7554_eLife_10163 crossref_primary_10_1113_jphysiol_2013_259804 crossref_primary_10_1016_j_neuroscience_2012_06_022 crossref_primary_10_1038_s41593_021_00974_7 crossref_primary_10_1021_acsnano_4c10525 crossref_primary_10_1038_s41586_022_05328_2 crossref_primary_10_1038_s41467_018_04286_6 crossref_primary_10_1038_s41467_022_34039_5 crossref_primary_10_1126_science_1209168 crossref_primary_10_1152_jn_00702_2010 crossref_primary_10_7554_eLife_79848 crossref_primary_10_1016_j_neuroimage_2017_01_049 crossref_primary_10_1016_j_neuron_2020_11_018 crossref_primary_10_1016_j_cub_2016_08_035 crossref_primary_10_1016_j_neuroscience_2015_04_001 crossref_primary_10_1016_j_cub_2010_07_001 crossref_primary_10_1111_j_1476_5381_2010_00988_x crossref_primary_10_1126_science_aat6766 crossref_primary_10_1103_PhysRevE_99_023311 crossref_primary_10_1038_s41586_022_05113_1 crossref_primary_10_1111_1365_2435_13010 crossref_primary_10_3390_app132312951 crossref_primary_10_1002_glia_24350 crossref_primary_10_1016_j_neuron_2020_11_013 crossref_primary_10_1038_nn_4046 crossref_primary_10_1093_cercor_bhx169 crossref_primary_10_1016_j_ymeth_2017_04_014 crossref_primary_10_3389_fncel_2023_1142267 crossref_primary_10_1038_nmeth_1398 crossref_primary_10_1523_JNEUROSCI_1527_18_2019 crossref_primary_10_4161_intv_28210 crossref_primary_10_1016_j_jneumeth_2016_02_005 crossref_primary_10_1016_j_conb_2009_08_005 crossref_primary_10_1093_cz_zow070 crossref_primary_10_1016_j_cub_2018_04_012 crossref_primary_10_1111_micc_12188 crossref_primary_10_7554_eLife_50855 crossref_primary_10_2976_1_3284977 crossref_primary_10_1523_JNEUROSCI_3255_13_2013 crossref_primary_10_3389_fninf_2017_00048 crossref_primary_10_3389_fnins_2020_00819 crossref_primary_10_1088_1741_2552_abae8b crossref_primary_10_1515_nf_2017_A046 crossref_primary_10_1016_j_neuron_2016_09_057 crossref_primary_10_1038_s42003_023_04656_x crossref_primary_10_1002_glia_22288 crossref_primary_10_7554_eLife_27702 crossref_primary_10_3390_biology11111601 crossref_primary_10_1038_nmeth_1243 crossref_primary_10_3389_fncel_2019_00141 crossref_primary_10_1002_cyto_a_23963 crossref_primary_10_1016_j_neuroimage_2014_10_030 crossref_primary_10_1152_jn_00197_2010 crossref_primary_10_1016_j_jneumeth_2023_109827 crossref_primary_10_1101_pdb_top081810 crossref_primary_10_1126_sciadv_adj1895 crossref_primary_10_1002_glia_23246 crossref_primary_10_1038_nn_4061 crossref_primary_10_1002_glia_24337 crossref_primary_10_1073_pnas_1711692115 crossref_primary_10_1016_j_brainres_2017_09_003 crossref_primary_10_1016_j_cub_2019_07_078 crossref_primary_10_1152_jn_00084_2008 crossref_primary_10_1152_jn_00046_2015 crossref_primary_10_7554_eLife_81958 crossref_primary_10_1038_s41593_018_0189_y crossref_primary_10_1016_j_neuron_2013_03_020 crossref_primary_10_1038_nmeth_1256 crossref_primary_10_1523_ENEURO_0266_21_2021 crossref_primary_10_1109_TVCG_2020_2973063 crossref_primary_10_7554_eLife_36781 crossref_primary_10_1016_j_expneurol_2012_02_009 crossref_primary_10_1152_jn_00484_2010 crossref_primary_10_1016_j_fmre_2023_11_021 crossref_primary_10_1016_j_neuroimage_2015_04_054 crossref_primary_10_1073_pnas_1100428108 crossref_primary_10_1016_j_jneumeth_2017_12_018 crossref_primary_10_1038_s41593_019_0341_3 crossref_primary_10_1038_s41421_022_00498_9 crossref_primary_10_1109_TBCAS_2012_2226174 crossref_primary_10_1016_j_celrep_2022_111494 crossref_primary_10_1364_BOE_10_003343 crossref_primary_10_7554_eLife_57458 crossref_primary_10_1007_s00216_010_3740_6 crossref_primary_10_1152_jn_00669_2012 crossref_primary_10_1038_jcbfm_2011_196 crossref_primary_10_1523_JNEUROSCI_2550_12_2013 crossref_primary_10_7554_eLife_26839 crossref_primary_10_1002_jbio_201600007 crossref_primary_10_1016_j_neuron_2021_09_019 crossref_primary_10_1038_s41598_018_34472_x crossref_primary_10_1016_j_neuron_2010_08_026 crossref_primary_10_1038_nprot_2009_5 crossref_primary_10_1126_science_aad3358 crossref_primary_10_1016_j_celrep_2023_113671 crossref_primary_10_1177_1073858409333076 crossref_primary_10_1038_nmeth_3482 crossref_primary_10_1364_BOE_8_000436 crossref_primary_10_1523_JNEUROSCI_3176_20_2021 crossref_primary_10_1016_j_neuron_2012_02_011 crossref_primary_10_1038_nprot_2016_021 crossref_primary_10_1016_j_tins_2011_02_001 crossref_primary_10_1093_cercor_bhz147 crossref_primary_10_1038_s41467_022_29180_0 crossref_primary_10_1073_pnas_1507110112 crossref_primary_10_1021_acs_accounts_6b00561 crossref_primary_10_1002_cpcy_40 crossref_primary_10_1016_j_heliyon_2024_e25910 crossref_primary_10_1038_nn_4365 crossref_primary_10_1523_ENEURO_0164_19_2019 crossref_primary_10_1523_JNEUROSCI_4599_15_2016 crossref_primary_10_1016_j_jneumeth_2015_01_020 crossref_primary_10_3389_fnbeh_2021_744715 crossref_primary_10_3389_fncel_2022_917713 crossref_primary_10_1016_j_conb_2015_01_015 crossref_primary_10_1073_pnas_0903680106 crossref_primary_10_1038_nmeth_4226 crossref_primary_10_3389_fncel_2022_866109 crossref_primary_10_1016_j_cell_2023_02_024 crossref_primary_10_1007_s12576_015_0414_3 crossref_primary_10_1016_j_neuroimage_2019_01_002 crossref_primary_10_1113_JP278957 crossref_primary_10_1038_s41467_022_31272_w crossref_primary_10_1523_JNEUROSCI_2974_11_2011 crossref_primary_10_1364_OE_16_005556 crossref_primary_10_3389_fncel_2021_682888 crossref_primary_10_1016_j_conb_2009_09_003 crossref_primary_10_1038_s41586_020_2319_4 crossref_primary_10_1016_j_cub_2020_06_023 crossref_primary_10_1088_1741_2552_aac96d crossref_primary_10_3389_fnins_2023_1277501 crossref_primary_10_1088_2050_6120_acba66 crossref_primary_10_1038_nn_4390 crossref_primary_10_1038_s41467_022_29236_1 crossref_primary_10_1038_s41583_020_0361_8 crossref_primary_10_1038_nn_4157 crossref_primary_10_1038_s41598_023_40638_z crossref_primary_10_1016_j_tins_2023_03_003 crossref_primary_10_1016_j_expneurol_2016_08_003 crossref_primary_10_1038_s41467_018_06058_8 crossref_primary_10_1016_j_celrep_2021_108704 crossref_primary_10_1016_j_cell_2020_11_013 crossref_primary_10_1017_S1740925X09000064 crossref_primary_10_1523_JNEUROSCI_0017_17_2017 crossref_primary_10_2139_ssrn_3981904 crossref_primary_10_3389_fncel_2015_00011 crossref_primary_10_1371_journal_pone_0002525 crossref_primary_10_7554_eLife_43140 crossref_primary_10_1016_j_neuron_2014_06_031 crossref_primary_10_1152_jn_00069_2019 crossref_primary_10_1016_j_jneumeth_2022_109705 crossref_primary_10_7554_eLife_14985 crossref_primary_10_1038_nprot_2016_121 crossref_primary_10_1038_nature08897 crossref_primary_10_3389_fddev_2024_1397056 crossref_primary_10_1038_nm_3400 crossref_primary_10_1038_nn_4385 crossref_primary_10_1080_01677060802298517 crossref_primary_10_12688_f1000research_51755_1 crossref_primary_10_1016_j_conb_2011_10_015 crossref_primary_10_1152_jn_00170_2021 crossref_primary_10_12688_f1000research_51755_2 crossref_primary_10_1016_j_neuron_2012_03_040 crossref_primary_10_1038_nature08539 crossref_primary_10_1371_journal_pone_0089007 crossref_primary_10_1523_JNEUROSCI_3762_09_2010 crossref_primary_10_1152_jn_00230_2017 crossref_primary_10_1371_journal_pone_0233561 crossref_primary_10_1038_nature08540 crossref_primary_10_1152_jn_01056_2015 crossref_primary_10_1016_j_jneumeth_2011_10_029 crossref_primary_10_1364_BOE_445775 crossref_primary_10_1016_j_job_2024_100606 crossref_primary_10_1152_jn_00464_2015 crossref_primary_10_1038_nrn3293 crossref_primary_10_1101_pdb_top078147 crossref_primary_10_1016_j_plantsci_2021_110986 crossref_primary_10_1371_journal_pone_0252345 crossref_primary_10_1093_cercor_bhw002 crossref_primary_10_7554_eLife_21589 crossref_primary_10_1371_journal_pone_0196563 crossref_primary_10_1098_rstb_2021_0450 crossref_primary_10_1371_journal_pcbi_1009799 crossref_primary_10_2745_dds_31_146 crossref_primary_10_1038_s41467_019_13523_5 crossref_primary_10_1038_nn_3482 crossref_primary_10_1038_s41598_023_30524_z crossref_primary_10_1371_journal_pcbi_1006041 crossref_primary_10_1016_j_cub_2021_02_031 crossref_primary_10_1038_aba1788 crossref_primary_10_1111_j_1748_1716_2008_01925_x crossref_primary_10_7554_eLife_78005 crossref_primary_10_1016_j_conb_2015_04_001 crossref_primary_10_1016_j_conb_2014_09_009 crossref_primary_10_1109_JPHOT_2013_2250941 crossref_primary_10_1214_18_AOAS1162 crossref_primary_10_1016_j_neuron_2013_09_046 crossref_primary_10_7554_eLife_77153 crossref_primary_10_1038_s41598_018_25844_4 crossref_primary_10_1523_JNEUROSCI_2985_09_2009 crossref_primary_10_1073_pnas_1807192115 crossref_primary_10_1016_j_neuron_2023_06_009 crossref_primary_10_1038_s41380_023_02269_8 crossref_primary_10_1523_JNEUROSCI_1877_20_2020 crossref_primary_10_5607_en22015 crossref_primary_10_1016_j_neuron_2017_09_052 crossref_primary_10_1007_s13295_013_0042_4 crossref_primary_10_1016_j_jneumeth_2021_109434 crossref_primary_10_1126_sciadv_abk1378 crossref_primary_10_1364_BOE_7_003596 crossref_primary_10_1038_nn_2140 crossref_primary_10_7567_JJAP_55_04EM02 crossref_primary_10_1371_journal_pone_0220751 crossref_primary_10_1038_nature07150 crossref_primary_10_1038_s42003_020_01612_x crossref_primary_10_1016_j_neuron_2017_01_027 crossref_primary_10_1073_pnas_1218654109 crossref_primary_10_1080_0964704X_2011_593118 crossref_primary_10_1016_j_jneumeth_2010_01_033 crossref_primary_10_1016_j_neuron_2007_11_009 crossref_primary_10_1016_j_neuron_2015_05_037 crossref_primary_10_1038_nn_4358 crossref_primary_10_1038_srep12196 crossref_primary_10_1016_j_crmeth_2024_100863 crossref_primary_10_1186_s12868_019_0533_5 crossref_primary_10_1007_s00424_011_1048_9 crossref_primary_10_1016_j_neuron_2020_08_024 crossref_primary_10_1038_s41586_018_0191_2 crossref_primary_10_1016_j_cub_2015_03_009 crossref_primary_10_3389_fbioe_2016_00030 crossref_primary_10_3389_fncir_2016_00020 crossref_primary_10_1515_nf_2013_0203 crossref_primary_10_1523_JNEUROSCI_1957_20_2021 crossref_primary_10_1016_j_celrep_2019_02_104 crossref_primary_10_1038_s41598_021_89974_y crossref_primary_10_1152_jn_91037_2008 crossref_primary_10_1016_j_neuroscience_2020_07_054 crossref_primary_10_1038_s41593_018_0255_5 crossref_primary_10_1103_PhysRevE_99_042114 crossref_primary_10_1016_j_celrep_2018_08_010 crossref_primary_10_1016_j_ynstr_2023_100518 crossref_primary_10_7554_eLife_01982 crossref_primary_10_1016_j_jneumeth_2011_09_015 crossref_primary_10_1016_j_neuron_2021_03_032 crossref_primary_10_1371_journal_pcbi_1010421 crossref_primary_10_1523_JNEUROSCI_6689_10_2011 crossref_primary_10_1038_nprot_2009_142 crossref_primary_10_1038_nn_3134 crossref_primary_10_1038_503045a crossref_primary_10_1016_j_neuron_2013_10_049 crossref_primary_10_1016_j_jneumeth_2016_04_012 crossref_primary_10_3389_fncel_2025_1558504 crossref_primary_10_1016_j_neuron_2016_06_020 crossref_primary_10_1016_j_brs_2018_11_007 crossref_primary_10_1364_BOE_6_004228 crossref_primary_10_1038_s41467_022_35383_2 crossref_primary_10_1002_glia_24162 crossref_primary_10_1038_s41467_019_10564_8 crossref_primary_10_1186_s12915_023_01660_9 crossref_primary_10_1371_journal_pcbi_1005148 crossref_primary_10_1038_nn_4653 crossref_primary_10_1523_JNEUROSCI_1828_17_2017 crossref_primary_10_1038_nn_4654 crossref_primary_10_1002_cne_22615 crossref_primary_10_1016_j_brainres_2010_11_007 crossref_primary_10_1002_jbio_201700131 crossref_primary_10_1016_j_conb_2015_03_016 crossref_primary_10_1038_nn_3567 crossref_primary_10_1109_JSTQE_2013_2279314 crossref_primary_10_1038_s41551_022_00851_z crossref_primary_10_1371_journal_pone_0049637 crossref_primary_10_1038_nature13871 crossref_primary_10_1101_pdb_top083535 crossref_primary_10_1016_j_neuron_2009_08_009 crossref_primary_10_1038_jcbfm_2012_50 crossref_primary_10_1073_pnas_1318325110 crossref_primary_10_1016_j_conb_2011_05_003 crossref_primary_10_1152_jn_00100_2023 crossref_primary_10_1016_j_xpro_2024_103027 crossref_primary_10_1038_s41592_021_01226_z crossref_primary_10_3389_fncir_2018_00015 crossref_primary_10_1038_s41593_018_0252_8 crossref_primary_10_1038_s41598_019_41966_9 crossref_primary_10_1016_j_jneumeth_2017_07_031 crossref_primary_10_1016_j_neures_2018_01_001 crossref_primary_10_1016_j_neuroscience_2017_05_033 crossref_primary_10_1038_nn_4516 crossref_primary_10_1016_j_ymeth_2013_05_016 crossref_primary_10_1021_jacs_5b03548 crossref_primary_10_3390_mi14020470 crossref_primary_10_1038_srep17847 crossref_primary_10_1038_nn_3552 crossref_primary_10_1002_glia_23181 crossref_primary_10_1523_JNEUROSCI_4595_15_2016 crossref_primary_10_1523_ENEURO_0245_16_2017 crossref_primary_10_1101_pdb_prot069294 crossref_primary_10_1038_nmeth_4183 crossref_primary_10_7554_eLife_28158 crossref_primary_10_1371_journal_pone_0013829 crossref_primary_10_1214_18_AOAS1159 crossref_primary_10_3390_mi9090428 crossref_primary_10_3389_fninf_2018_00098 crossref_primary_10_1038_s41377_019_0167_5 crossref_primary_10_1088_0034_4885_74_8_086602 crossref_primary_10_3389_fncel_2021_618658 crossref_primary_10_1016_j_tins_2020_05_005 crossref_primary_10_1523_JNEUROSCI_2570_19_2020 crossref_primary_10_3390_ijms19103033 crossref_primary_10_3390_photonics12010003 crossref_primary_10_1016_j_neuron_2017_11_033 crossref_primary_10_1016_j_tins_2009_05_001 crossref_primary_10_1117_1_NPh_11_3_033406 crossref_primary_10_1364_BOE_7_003686 crossref_primary_10_1016_j_jneumeth_2022_109549 crossref_primary_10_1113_jphysiol_2012_228114 crossref_primary_10_1523_JNEUROSCI_0594_14_2015 crossref_primary_10_1523_JNEUROSCI_0117_15_2015 crossref_primary_10_1016_j_neures_2017_04_009 crossref_primary_10_1111_rssb_12501 crossref_primary_10_3389_fnbeh_2018_00036 crossref_primary_10_7554_eLife_35800 crossref_primary_10_3389_fncir_2018_00033 crossref_primary_10_3390_mi9090436 crossref_primary_10_1016_j_neuron_2017_09_029 crossref_primary_10_1523_JNEUROSCI_1780_15_2015 crossref_primary_10_1038_nature08499 crossref_primary_10_1111_joa_14110 crossref_primary_10_1177_1073858418805427 crossref_primary_10_7554_eLife_07122 crossref_primary_10_1364_BOE_544383 crossref_primary_10_1016_j_conb_2011_12_002 crossref_primary_10_7554_eLife_86805 crossref_primary_10_1038_s41598_020_69132_6 crossref_primary_10_1093_cercor_bhw175 crossref_primary_10_1371_journal_pone_0204066 crossref_primary_10_1016_j_jneumeth_2021_109251 crossref_primary_10_1523_ENEURO_0065_18_2018 crossref_primary_10_1016_j_jneumeth_2017_07_014 crossref_primary_10_1117_1_NPh_4_3_035001 crossref_primary_10_1073_pnas_1524219113 crossref_primary_10_1111_jmi_12880 crossref_primary_10_1016_j_mehy_2013_09_021 crossref_primary_10_7554_eLife_85111_3 crossref_primary_10_1038_s41467_019_11050_x crossref_primary_10_1016_j_neuron_2007_09_017 crossref_primary_10_1016_j_neures_2018_10_010 crossref_primary_10_1016_j_neuron_2014_10_048 crossref_primary_10_1016_j_neuroimage_2018_11_062 crossref_primary_10_1177_0271678X16629977 crossref_primary_10_1016_j_jneumeth_2019_108454 crossref_primary_10_1016_j_neuroimage_2016_11_069 crossref_primary_10_1113_jphysiol_2012_230532 crossref_primary_10_1038_s41586_019_1641_1 crossref_primary_10_1038_s41467_020_19948_7 crossref_primary_10_1038_s41583_023_00716_7 crossref_primary_10_1016_j_neuron_2012_09_037 crossref_primary_10_2139_ssrn_3155578 crossref_primary_10_1016_j_expneurol_2019_112972 crossref_primary_10_1186_s13064_020_00151_9 crossref_primary_10_1002_hipo_20519 crossref_primary_10_1016_j_copbio_2010_01_009 crossref_primary_10_1038_nn_2431 crossref_primary_10_1214_09_AOAS303 crossref_primary_10_1017_S1740925X10000219 crossref_primary_10_1038_s41467_017_02501_4 crossref_primary_10_1007_s10827_011_0376_2 crossref_primary_10_1073_pnas_1421753111 crossref_primary_10_1038_nbt_3594 crossref_primary_10_1371_journal_pone_0098842 crossref_primary_10_1002_glia_23940 crossref_primary_10_1101_pdb_top071464 crossref_primary_10_1016_j_brainres_2010_05_061 crossref_primary_10_1038_s41467_019_10498_1 crossref_primary_10_1016_j_cell_2017_07_020 crossref_primary_10_1038_s41598_022_10195_y crossref_primary_10_1093_biostatistics_kxy083 crossref_primary_10_1364_OL_490087 crossref_primary_10_1523_ENEURO_0147_19_2019 crossref_primary_10_1073_pnas_1805517115 crossref_primary_10_1523_JNEUROSCI_3285_12_2013 crossref_primary_10_1038_nn_3867 crossref_primary_10_1523_JNEUROSCI_1060_20_2020 crossref_primary_10_1073_pnas_2108882119 crossref_primary_10_1007_s00467_011_1818_9 crossref_primary_10_1063_1_3184828 crossref_primary_10_1523_JNEUROSCI_0811_17_2017 crossref_primary_10_2197_ipsjtbio_16_1 crossref_primary_10_3389_fnsys_2023_1165307 crossref_primary_10_1063_5_0041394 crossref_primary_10_1016_j_conb_2018_04_020 crossref_primary_10_3389_fnana_2014_00016 crossref_primary_10_1364_BOE_9_002304 crossref_primary_10_3389_fncir_2021_747724 crossref_primary_10_1038_s41586_022_05146_6 crossref_primary_10_3109_08990220_2010_513111 crossref_primary_10_1371_journal_pone_0051789 crossref_primary_10_1038_s42003_024_05996_y crossref_primary_10_1038_nn_4634 crossref_primary_10_1038_s41593_021_00914_5 crossref_primary_10_1016_j_jneumeth_2013_03_009 crossref_primary_10_1111_ejn_13074 crossref_primary_10_1016_j_neuron_2018_09_020 crossref_primary_10_1016_j_neuroimage_2015_02_070 crossref_primary_10_1523_JNEUROSCI_5319_10_2011 crossref_primary_10_1016_j_cell_2024_07_036 crossref_primary_10_1038_nrn2338 crossref_primary_10_1523_JNEUROSCI_3174_14_2015 crossref_primary_10_1364_BOE_8_003329 crossref_primary_10_1016_j_neuroscience_2013_05_049 crossref_primary_10_1038_s41586_021_03452_z crossref_primary_10_1007_s12264_016_0053_6 crossref_primary_10_2139_ssrn_3155786 crossref_primary_10_1523_JNEUROSCI_4469_11_2012 crossref_primary_10_1016_j_neuroscience_2013_04_022 crossref_primary_10_1152_physiol_00032_2007 crossref_primary_10_7554_eLife_82367 crossref_primary_10_1016_j_brainres_2011_06_008 crossref_primary_10_2184_lsj_41_2_86 crossref_primary_10_1073_pnas_1406077111 crossref_primary_10_1016_j_jneumeth_2021_109173 crossref_primary_10_1038_nn_2557 crossref_primary_10_1016_j_bbr_2014_03_007 crossref_primary_10_1117_1_JBO_19_11_116011 crossref_primary_10_1038_nmeth0110_09 crossref_primary_10_1016_j_neuron_2023_08_015 crossref_primary_10_1016_j_neuron_2017_08_036 crossref_primary_10_1186_s12987_020_00214_3 crossref_primary_10_7554_eLife_71476 crossref_primary_10_1016_j_molmed_2008_07_005 crossref_primary_10_1371_journal_pone_0180452 crossref_primary_10_1016_j_jneumeth_2020_108905 crossref_primary_10_1038_nmeth1108_925 crossref_primary_10_1126_science_1247485 crossref_primary_10_1016_j_ceca_2016_06_002 crossref_primary_10_7554_eLife_29546 crossref_primary_10_1038_s41592_020_0817_9 crossref_primary_10_1007_s11064_017_2195_y crossref_primary_10_1038_s41593_023_01280_0 crossref_primary_10_1007_s00429_016_1292_z crossref_primary_10_1073_pnas_1718721115 crossref_primary_10_1038_s41586_019_1644_y crossref_primary_10_1016_j_neuron_2015_03_055 crossref_primary_10_1515_nf_2017_0046 crossref_primary_10_1038_s41467_024_48505_9 crossref_primary_10_1523_JNEUROSCI_2043_14_2015 crossref_primary_10_7554_eLife_04006 crossref_primary_10_1038_s41592_024_02535_9 crossref_primary_10_1117_1_NPh_10_4_044304 crossref_primary_10_1016_j_cub_2009_02_033 crossref_primary_10_1038_srep20986 crossref_primary_10_1038_nature11057 crossref_primary_10_1016_j_jneumeth_2014_11_010 crossref_primary_10_1038_s41467_018_04457_5 crossref_primary_10_1038_ncomms11450 crossref_primary_10_1016_j_pneurobio_2014_06_005 crossref_primary_10_21468_SciPostPhysLectNotes_84 crossref_primary_10_24072_pcjournal_156 crossref_primary_10_1007_s12311_009_0139_z crossref_primary_10_1371_journal_pone_0110475 crossref_primary_10_1016_j_neuron_2017_06_013 crossref_primary_10_1038_s41598_017_03340_5 crossref_primary_10_1017_S1551929517000785 crossref_primary_10_1038_s41467_022_35620_8 crossref_primary_10_1016_j_jneumeth_2019_03_019 crossref_primary_10_1016_j_neuron_2024_09_009 crossref_primary_10_7554_eLife_89986_5 crossref_primary_10_1038_s41592_022_01688_9 crossref_primary_10_3389_fnmol_2014_00097 crossref_primary_10_1002_wmts_48 crossref_primary_10_1016_j_ceca_2016_12_005 crossref_primary_10_1016_j_celrep_2021_109444 crossref_primary_10_4196_kjpp_2014_18_2_103 crossref_primary_10_3389_fninf_2022_851188 crossref_primary_10_1152_jn_00138_2013 crossref_primary_10_1371_journal_pone_0177396 crossref_primary_10_1523_JNEUROSCI_2012_09_2009 crossref_primary_10_1016_j_neuron_2009_03_019 crossref_primary_10_1016_j_jneumeth_2019_108403 crossref_primary_10_1371_journal_pone_0083171 crossref_primary_10_1016_j_celrep_2022_111700 crossref_primary_10_1016_j_neuron_2013_08_018 crossref_primary_10_1117_1_NPh_10_4_044411 crossref_primary_10_1038_s41467_017_01371_0 crossref_primary_10_1038_s41467_018_03262_4 crossref_primary_10_1007_s11263_022_01713_6 crossref_primary_10_1016_j_conb_2020_11_004 crossref_primary_10_2139_ssrn_4491483 crossref_primary_10_3389_fnins_2016_00169 crossref_primary_10_1016_j_celrep_2018_12_069 crossref_primary_10_1016_j_ceca_2021_102390 crossref_primary_10_1038_nn_3739 crossref_primary_10_3390_cells12091253 crossref_primary_10_1523_JNEUROSCI_4990_12_2013 crossref_primary_10_1038_nn_2648 crossref_primary_10_1371_journal_pcbi_1008835 crossref_primary_10_1016_j_neuron_2013_08_002 crossref_primary_10_1016_j_neuron_2015_03_027 crossref_primary_10_1016_j_neuron_2014_01_019 crossref_primary_10_1111_epi_12939 crossref_primary_10_1016_j_neures_2019_12_009 crossref_primary_10_1038_nature12485 crossref_primary_10_1515_revneuro_2020_0119 crossref_primary_10_1016_j_jneumeth_2009_06_031 crossref_primary_10_1016_j_neuron_2018_08_008 crossref_primary_10_31083_JIN26242 crossref_primary_10_1016_j_neuron_2013_08_007 crossref_primary_10_1016_j_conb_2010_06_005 crossref_primary_10_1101_pdb_prot080143 crossref_primary_10_1038_s41467_018_07926_z crossref_primary_10_1111_j_1749_6632_2009_04110_x crossref_primary_10_1016_j_jneumeth_2013_02_006 crossref_primary_10_1016_j_neuron_2018_09_045 crossref_primary_10_1073_pnas_1214912110 crossref_primary_10_1038_nn_2518 crossref_primary_10_1038_nn_2879 crossref_primary_10_1016_j_neuron_2012_07_011 crossref_primary_10_1364_OL_40_002553 crossref_primary_10_1007_s11633_021_1307_y crossref_primary_10_1111_epi_12804 crossref_primary_10_1016_j_cub_2011_11_047 crossref_primary_10_2139_ssrn_3205414 crossref_primary_10_1016_j_neuron_2018_09_050 crossref_primary_10_1371_journal_pone_0146533 crossref_primary_10_1038_nature12236 crossref_primary_10_1113_expphysiol_2010_052597 crossref_primary_10_1016_j_crneur_2022_100040 crossref_primary_10_1016_j_xpro_2024_102911 crossref_primary_10_1007_s00429_015_1070_3
Cites_doi	10.1523/JNEUROSCI.4258-04.2005 10.1007/s00424-007-0234-2 10.1073/pnas.0509378103 10.1371/journal.pbio.0050189 10.1016/j.tins.2007.04.006 10.1016/j.conb.2006.08.011 10.1016/S0896-6273(00)81237-4 10.1016/S0896-6273(00)00057-X 10.1038/385161a0 10.1016/j.neuron.2007.02.018 10.1152/jn.00416.2005 10.1016/S0896-6273(01)00421-4 10.1016/j.neuron.2005.01.003 10.1016/j.neuron.2006.03.043 10.1109/5.18626 10.1016/0165-0270(82)90085-1 10.1007/s00359-006-0117-6 10.1038/nn1883 10.1038/14788 10.1038/nature05744 10.1038/nature04783 10.1523/JNEUROSCI.3238-06.2006 10.1111/j.1399-6576.1992.tb03480.x 10.1073/pnas.1232232100 10.1038/nn1233 10.1016/S0896-6273(00)00084-2 10.1038/nn1525 10.1152/jn.01207.2006 10.1371/journal.pbio.0030355 10.1152/jn.01007.2003 10.1186/1475-925X-2-13 10.1364/OL.30.002272 10.1152/physiolgenomics.00243.2004 10.1073/pnas.0506029102 10.1529/biophysj.104.040477 10.1038/nn1635 10.1038/nature03274 10.1126/science.2321027 10.1038/nmeth706 10.1038/35070564 10.1126/science.273.5283.1868 10.1038/nmeth989 10.1038/nn1703 10.1242/jeb.01371 10.1152/jn.00234.2004 10.1038/nmeth1009 10.1371/journal.pbio.0020329 10.1038/nn1690 10.1016/j.conb.2004.10.017 10.1016/S0896-6273(00)80955-1 10.1007/BF01970140
ContentType	Journal Article
Copyright	2007 Elsevier Inc. Copyright Elsevier Limited Oct 4, 2007
Copyright_xml	– notice: 2007 Elsevier Inc. – notice: Copyright Elsevier Limited Oct 4, 2007
DBID	6I. AAFTH AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QP 7QR 7TK 8FD FR3 K9. NAPCQ P64 RC3 7X8 5PM ADTOC UNPAY
DOI	10.1016/j.neuron.2007.08.003
DatabaseName	ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Neurosciences Abstracts Technology Research Database Engineering Research Database ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) Unpaywall for CDI: Periodical Content Unpaywall
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Genetics Abstracts Technology Research Database ProQuest Health & Medical Complete (Alumni) Chemoreception Abstracts Engineering Research Database Calcium & Calcified Tissue Abstracts Neurosciences Abstracts Biotechnology and BioEngineering Abstracts MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic Neurosciences Abstracts MEDLINE Nursing & Allied Health Premium
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository
DeliveryMethod	fulltext_linktorsrc
Discipline	Anatomy & Physiology Biology
EISSN	1097-4199
EndPage	57
ExternalDocumentID	10.1016/j.neuron.2007.08.003 PMC2268027 3235332741 17920014 10_1016_j_neuron_2007_08_003 S0896627307006149
Genre	Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural
GrantInformation_xml	– fundername: NIMH NIH HHS grantid: R01 MH083686 – fundername: NIDA NIH HHS grantid: R90 DA023419 – fundername: NIGMS NIH HHS grantid: T32 GM007388 – fundername: NIMH NIH HHS grantid: K25 MH067876
GroupedDBID	--- --K -DZ -~X .55 .GJ 0R~ 123 1RT 1~5 26- 29N 2WC 3O- 3V. 4.4 457 4G. 53G 5RE 5VS 62- 6I. 7-5 7RV 7X7 8C1 8FE 8FH AACTN AAEDT AAEDW AAFTH AAIAV AAIKJ AAKRW AAKUH AALRI AAQFI AAQXK AAUCE AAVLU AAXJY AAXUO ABJNI ABMAC ABMWF ABVKL ACGFO ACGFS ACIWK ACNCT ACPRK ADBBV ADEZE ADFRT ADJPV ADMUD AEFWE AENEX AEXQZ AFKRA AFTJW AGHFR AGKMS AHHHB AHMBA AHPSJ AITUG ALKID ALMA_UNASSIGNED_HOLDINGS AMRAJ AQUVI ASPBG AVWKF AZFZN BAWUL BBNVY BENPR BHPHI BKEYQ BKNYI BPHCQ BVXVI CS3 DIK DU5 E3Z EBS EJD F5P FCP FDB FEDTE FGOYB FIRID G-2 HCIFZ HVGLF HZ~ IAO IHE IHR INH IXB J1W JIG K-O KQ8 L7B LK8 LX5 M0R M0T M2M M2O M3Z M41 M7P MVM N9A NCXOZ O-L O9- OK1 OZT P2P P6G PQQKQ PROAC R2- RCE RIG ROL RPZ SCP SDP SES SSZ TR2 WOW WQ6 X7M ZA5 ZGI ZKB AAFWJ AAMRU AAYWO AAYXX ABDGV ABWVN ACRPL ACVFH ADCNI ADNMO ADVLN AEUPX AFPUW AGQPQ AIGII AKAPO AKBMS AKRWK AKYEP APXCP CITATION EFKBS ITC AGCQF CGR CUY CVF ECM EIF NPM 7QP 7QR 7TK 8FD FR3 K9. NAPCQ P64 RC3 7X8 5PM ADTOC UNPAY
ID	FETCH-LOGICAL-c520t-6816f5ea418ac25765e7ece1c185c24a0f8920519e5bc85d9862403ca14cf49b3
IEDL.DBID	UNPAY
ISSN	0896-6273 1097-4199
IngestDate	Sun Oct 26 04:11:27 EDT 2025 Tue Sep 30 17:09:42 EDT 2025 Wed Oct 01 15:00:51 EDT 2025 Thu Oct 02 11:55:42 EDT 2025 Tue Oct 07 06:36:26 EDT 2025 Mon Jul 21 05:44:33 EDT 2025 Thu Oct 16 04:36:33 EDT 2025 Thu Apr 24 22:53:10 EDT 2025 Fri Feb 23 02:28:26 EST 2024
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	1
Keywords	SYSNEURO
Language	English
License	http://www.elsevier.com/open-access/userlicense/1.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c520t-6816f5ea418ac25765e7ece1c185c24a0f8920519e5bc85d9862403ca14cf49b3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Authors contributed equally to this work.
OpenAccessLink	https://proxy.k.utb.cz/login?url=http://www.cell.com/article/S0896627307006149/pdf
PMID	17920014
PQID	1503760284
PQPubID	2031076
PageCount	15
ParticipantIDs	unpaywall_primary_10_1016_j_neuron_2007_08_003 pubmedcentral_primary_oai_pubmedcentral_nih_gov_2268027 proquest_miscellaneous_68360517 proquest_miscellaneous_20784784 proquest_journals_1503760284 pubmed_primary_17920014 crossref_citationtrail_10_1016_j_neuron_2007_08_003 crossref_primary_10_1016_j_neuron_2007_08_003 elsevier_sciencedirect_doi_10_1016_j_neuron_2007_08_003
PublicationCentury	2000
PublicationDate	2007-10-04
PublicationDateYYYYMMDD	2007-10-04
PublicationDate_xml	– month: 10 year: 2007 text: 2007-10-04 day: 04
PublicationDecade	2000
PublicationPlace	United States
PublicationPlace_xml	– name: United States – name: Cambridge
PublicationTitle	Neuron (Cambridge, Mass.)
PublicationTitleAlternate	Neuron
PublicationYear	2007
Publisher	Elsevier Inc Elsevier Limited
Publisher_xml	– name: Elsevier Inc – name: Elsevier Limited
References	Holtmaat, Trachtenberg, Wilbrecht, Shepherd, Zhang, Knott, Svoboda (bib24) 2005; 45 Flusberg, Jung, Cocker, Anderson, Schnitzer (bib17) 2005; 30 Berg-Johnsen, Langmoen (bib2) 1992; 36 Rose, Kovalchuk, Eilers, Konnerth (bib40) 1999; 439 Dombeck, Sacconi, Blanchard-Desce, Webb (bib12) 2005; 94 Dunn, Wang, Colicos, Zaccolo, DiPilato, Zhang, Tsien, Feller (bib13) 2006; 26 Nevian, Helmchen (bib34) 2007; 454 Arieli, Sterkin, Grinvald, Aertsen (bib1) 1996; 273 Fee (bib14) 2000; 27 Tallini, Ohkura, Choi, Ji, Imoto, Doran, Lee, Plan, Wilson, Xin (bib48) 2006; 103 Shoham, O'Connor, Segev (bib43) 2006; 192 Major, Tank (bib31) 2004; 14 Levene, Dombeck, Kasischke, Molloy, Webb (bib30) 2004; 91 Denk, Horstmann (bib9) 2004; 2 Stevenson, Dyakonova, Rillich, Schildberger (bib45) 2005; 25 Feng, Mellor, Bernstein, Keller-Peck, Nguyen, Wallace, Nerbonne, Lichtman, Sanes (bib15) 2000; 28 Denk, Svoboda (bib8) 1997; 18 Nagayama, Zeng, Xiong, Fletcher, Masurkar, Davis, Pieribone, Chen (bib33) 2007; 53 Kuhn, Fromherz, Denk (bib29) 2004; 87 Xu, Pan, Yang, Gan (bib52) 2007; 10 Kerr, Greenberg, Helmchen (bib26) 2005; 102 Sato, Gray, Mainen, Svoboda (bib42) 2007; 5 Ohki, Chung, Ch'ng, Kara, Reid (bib36) 2005; 433 Helmchen, Svoboda, Denk, Tank (bib20) 1999; 2 Siegel, Isacoff (bib44) 1997; 19 Heim, Garaschuk, Friedrich, Mank, Milos, Kovalchuk, Konnerth, Griesbeck (bib19) 2007; 4 Svoboda, Denk, Kleinfeld, Tank (bib47) 1997; 385 Denk, Strickler, Webb (bib10) 1990; 248 Holscher, Schnee, Dahmen, Setia, Mallot (bib22) 2005; 208 Khabbaz, A.N., and Tank, D.W. (2004). Recording head direction cells in head fixed mice. Paper presented at: Society for Neuroscience (San Diego, Ca, Program No. 667.8). Holtmaat, Wilbrecht, Knott, Welker, Svoboda (bib23) 2006; 441 Crochet, Petersen (bib6) 2006; 9 Britt, Rossi (bib4) 1982; 6 Stosiek, Garaschuk, Holthoff, Konnerth (bib46) 2003; 100 Destexhe, Hughes, Rudolph, Crunelli (bib11) 2007; 30 Dahmen (bib7) 1980; 36 Nimmerjahn, Kirchhoff, Kerr, Helmchen (bib35) 2004; 1 Ferezou, Bolea, Petersen (bib16) 2006; 50 Pologruto, Sabatini, Svoboda (bib38) 2003; 2 Paxinos, Franklin, Franklin (bib37) 2001 Zhang, Wang, Brauner, Liewald, Kay, Watzke, Wood, Bamberg, Nagel, Gottschalk, Deisseroth (bib54) 2007; 446 Jung, Mehta, Aksay, Stepnoski, Schnitzer (bib25) 2004; 92 Mason, Oshinsky, Hoy (bib32) 2001; 410 Saggau (bib41) 2006; 16 Gobel, Kampa, Helmchen (bib18) 2007; 4 Helmchen, Fee, Tank, Denk (bib21) 2001; 31 Boyden, Zhang, Bamberg, Nagel, Deisseroth (bib3) 2005; 8 Turner, Kleeberger, Lightfoot (bib49) 2005; 22 Wilson, Dombeck, Diaz-Rios, Harris-Warrick, Brownstone (bib51) 2007; 97 Kleinfeld, Griesbeck (bib28) 2005; 3 Yasuda, Harvey, Zhong, Sobczyk, van Aelst, Svoboda (bib53) 2006; 9 Rabiner (bib39) 1989; 77 Buzsaki (bib5) 2004; 7 Wang, Lou, Xu, Tian, Peng, Han, Kang, Takano, Nedergaard (bib50) 2006; 9 Flusberg (10.1016/j.neuron.2007.08.003_bib17) 2005; 30 Shoham (10.1016/j.neuron.2007.08.003_bib43) 2006; 192 Arieli (10.1016/j.neuron.2007.08.003_bib1) 1996; 273 Feng (10.1016/j.neuron.2007.08.003_bib15) 2000; 28 Dombeck (10.1016/j.neuron.2007.08.003_bib12) 2005; 94 Dunn (10.1016/j.neuron.2007.08.003_bib13) 2006; 26 Holtmaat (10.1016/j.neuron.2007.08.003_bib24) 2005; 45 Zhang (10.1016/j.neuron.2007.08.003_bib54) 2007; 446 Boyden (10.1016/j.neuron.2007.08.003_bib3) 2005; 8 Holscher (10.1016/j.neuron.2007.08.003_bib22) 2005; 208 Denk (10.1016/j.neuron.2007.08.003_bib8) 1997; 18 Kerr (10.1016/j.neuron.2007.08.003_bib26) 2005; 102 Wilson (10.1016/j.neuron.2007.08.003_bib51) 2007; 97 Crochet (10.1016/j.neuron.2007.08.003_bib6) 2006; 9 Xu (10.1016/j.neuron.2007.08.003_bib52) 2007; 10 Ferezou (10.1016/j.neuron.2007.08.003_bib16) 2006; 50 Nagayama (10.1016/j.neuron.2007.08.003_bib33) 2007; 53 Yasuda (10.1016/j.neuron.2007.08.003_bib53) 2006; 9 Buzsaki (10.1016/j.neuron.2007.08.003_bib5) 2004; 7 Gobel (10.1016/j.neuron.2007.08.003_bib18) 2007; 4 Denk (10.1016/j.neuron.2007.08.003_bib10) 1990; 248 Major (10.1016/j.neuron.2007.08.003_bib31) 2004; 14 Denk (10.1016/j.neuron.2007.08.003_bib9) 2004; 2 Berg-Johnsen (10.1016/j.neuron.2007.08.003_bib2) 1992; 36 Helmchen (10.1016/j.neuron.2007.08.003_bib21) 2001; 31 Dahmen (10.1016/j.neuron.2007.08.003_bib7) 1980; 36 Turner (10.1016/j.neuron.2007.08.003_bib49) 2005; 22 Destexhe (10.1016/j.neuron.2007.08.003_bib11) 2007; 30 Tallini (10.1016/j.neuron.2007.08.003_bib48) 2006; 103 Nevian (10.1016/j.neuron.2007.08.003_bib34) 2007; 454 Svoboda (10.1016/j.neuron.2007.08.003_bib47) 1997; 385 Heim (10.1016/j.neuron.2007.08.003_bib19) 2007; 4 Britt (10.1016/j.neuron.2007.08.003_bib4) 1982; 6 Mason (10.1016/j.neuron.2007.08.003_bib32) 2001; 410 Kleinfeld (10.1016/j.neuron.2007.08.003_bib28) 2005; 3 Levene (10.1016/j.neuron.2007.08.003_bib30) 2004; 91 Pologruto (10.1016/j.neuron.2007.08.003_bib38) 2003; 2 Holtmaat (10.1016/j.neuron.2007.08.003_bib23) 2006; 441 10.1016/j.neuron.2007.08.003_bib27 Jung (10.1016/j.neuron.2007.08.003_bib25) 2004; 92 Rabiner (10.1016/j.neuron.2007.08.003_bib39) 1989; 77 Kuhn (10.1016/j.neuron.2007.08.003_bib29) 2004; 87 Nimmerjahn (10.1016/j.neuron.2007.08.003_bib35) 2004; 1 Ohki (10.1016/j.neuron.2007.08.003_bib36) 2005; 433 Sato (10.1016/j.neuron.2007.08.003_bib42) 2007; 5 Rose (10.1016/j.neuron.2007.08.003_bib40) 1999; 439 Siegel (10.1016/j.neuron.2007.08.003_bib44) 1997; 19 Fee (10.1016/j.neuron.2007.08.003_bib14) 2000; 27 Saggau (10.1016/j.neuron.2007.08.003_bib41) 2006; 16 Helmchen (10.1016/j.neuron.2007.08.003_bib20) 1999; 2 Paxinos (10.1016/j.neuron.2007.08.003_bib37) 2001 Wang (10.1016/j.neuron.2007.08.003_bib50) 2006; 9 Stosiek (10.1016/j.neuron.2007.08.003_bib46) 2003; 100 Stevenson (10.1016/j.neuron.2007.08.003_bib45) 2005; 25
References_xml	– volume: 31 start-page: 903 year: 2001 end-page: 912 ident: bib21 article-title: A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals publication-title: Neuron – volume: 77 start-page: 257 year: 1989 end-page: 286 ident: bib39 article-title: A tutorial on hidden Markov-models and selected applications in speech recognition publication-title: Proc. IEEE – volume: 439 start-page: 201 year: 1999 end-page: 207 ident: bib40 article-title: Two-photon Na+ imaging in spines and fine dendrites of central neurons publication-title: Pflugers Arch. – volume: 2 start-page: e329 year: 2004 ident: bib9 article-title: Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructure publication-title: PLoS Biol. – volume: 441 start-page: 979 year: 2006 end-page: 983 ident: bib23 article-title: Experience-dependent and cell-type-specific spine growth in the neocortex publication-title: Nature – reference: Khabbaz, A.N., and Tank, D.W. (2004). Recording head direction cells in head fixed mice. Paper presented at: Society for Neuroscience (San Diego, Ca, Program No. 667.8). – volume: 6 start-page: 219 year: 1982 end-page: 229 ident: bib4 article-title: Quantitative analysis of methods for reducing physiological brain pulsations publication-title: J. Neurosci. Methods – volume: 53 start-page: 789 year: 2007 end-page: 803 ident: bib33 article-title: In vivo simultaneous tracing and ca(2+) imaging of local neuronal circuits publication-title: Neuron – volume: 94 start-page: 3628 year: 2005 end-page: 3636 ident: bib12 article-title: Optical recording of fast neuronal membrane potential transients in acute mammalian brain slices by second-harmonic generation microscopy publication-title: J. Neurophysiol. – volume: 22 start-page: 76 year: 2005 end-page: 85 ident: bib49 article-title: Influence of genetic background on daily running-wheel activity differs with aging publication-title: Physiol. Genomics – volume: 19 start-page: 735 year: 1997 end-page: 741 ident: bib44 article-title: A genetically encoded optical probe of membrane voltage publication-title: Neuron – volume: 100 start-page: 7319 year: 2003 end-page: 7324 ident: bib46 article-title: In vivo two-photon calcium imaging of neuronal networks publication-title: Proc. Natl. Acad. Sci. USA – volume: 3 start-page: e355 year: 2005 ident: bib28 article-title: From art to engineering? The rise of in vivo mammalian electrophysiology via genetically targeted labeling and nonlinear imaging publication-title: PLoS Biol. – volume: 92 start-page: 3121 year: 2004 end-page: 3133 ident: bib25 article-title: In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy publication-title: J. Neurophysiol. – volume: 9 start-page: 283 year: 2006 end-page: 291 ident: bib53 article-title: Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging publication-title: Nat. Neurosci. – volume: 36 start-page: 685 year: 1980 end-page: 687 ident: bib7 article-title: A simple apparatus to investigate the orientation of walking insects publication-title: Experientia – volume: 30 start-page: 334 year: 2007 end-page: 342 ident: bib11 article-title: Are corticothalamic ‘up’ states fragments of wakefulness? publication-title: Trends Neurosci. – volume: 5 start-page: e189 year: 2007 ident: bib42 article-title: The functional microarchitecture of the mouse barrel cortex publication-title: PLoS Biol. – volume: 25 start-page: 1431 year: 2005 end-page: 1441 ident: bib45 article-title: Octopamine and experience-dependent modulation of aggression in crickets publication-title: J. Neurosci. – volume: 10 start-page: 549 year: 2007 end-page: 551 ident: bib52 article-title: Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex publication-title: Nat. Neurosci. – volume: 446 start-page: 633 year: 2007 end-page: 639 ident: bib54 article-title: Multimodal fast optical interrogation of neural circuitry publication-title: Nature – volume: 9 start-page: 608 year: 2006 end-page: 610 ident: bib6 article-title: Correlating whisker behavior with membrane potential in barrel cortex of awake mice publication-title: Nat. Neurosci. – volume: 30 start-page: 2272 year: 2005 end-page: 2274 ident: bib17 article-title: In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope publication-title: Opt. Lett. – volume: 454 start-page: 675 year: 2007 end-page: 688 ident: bib34 article-title: Calcium indicator loading of neurons using single-cell electroporation publication-title: Pflugers Arch. – volume: 102 start-page: 14063 year: 2005 end-page: 14068 ident: bib26 article-title: Imaging input and output of neocortical networks in vivo publication-title: Proc. Natl. Acad. Sci. USA – volume: 103 start-page: 4753 year: 2006 end-page: 4758 ident: bib48 article-title: Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2 publication-title: Proc. Natl. Acad. Sci. USA – volume: 4 start-page: 127 year: 2007 end-page: 129 ident: bib19 article-title: Improved calcium imaging in transgenic mice expressing a troponin C-based biosensor publication-title: Nat. Methods – volume: 385 start-page: 161 year: 1997 end-page: 165 ident: bib47 article-title: In vivo dendritic calcium dynamics in neocortical pyramidal neurons publication-title: Nature – volume: 18 start-page: 351 year: 1997 end-page: 357 ident: bib8 article-title: Photon upmanship: why multiphoton imaging is more than a gimmick publication-title: Neuron – volume: 45 start-page: 279 year: 2005 end-page: 291 ident: bib24 article-title: Transient and persistent dendritic spines in the neocortex in vivo publication-title: Neuron – volume: 273 start-page: 1868 year: 1996 end-page: 1871 ident: bib1 article-title: Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses publication-title: Science – volume: 8 start-page: 1263 year: 2005 end-page: 1268 ident: bib3 article-title: Millisecond-timescale, genetically targeted optical control of neural activity publication-title: Nat. Neurosci. – volume: 9 start-page: 816 year: 2006 end-page: 823 ident: bib50 article-title: Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo publication-title: Nat. Neurosci. – volume: 97 start-page: 3118 year: 2007 end-page: 3125 ident: bib51 article-title: Two-photon calcium imaging of network activity in XFP-expressing neurons in the mouse publication-title: J. Neurophysiol. – volume: 7 start-page: 446 year: 2004 end-page: 451 ident: bib5 article-title: Large-scale recording of neuronal ensembles publication-title: Nat. Neurosci. – year: 2001 ident: bib37 article-title: The mouse brain in stereotaxic coordinates – volume: 2 start-page: 13 year: 2003 ident: bib38 article-title: ScanImage: flexible software for operating laser scanning microscopes publication-title: Biomed. Eng. Online – volume: 1 start-page: 31 year: 2004 end-page: 37 ident: bib35 article-title: Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo publication-title: Nat. Methods – volume: 2 start-page: 989 year: 1999 end-page: 996 ident: bib20 article-title: In vivo dendritic calcium dynamics in deep-layer cortical pyramidal neurons publication-title: Nat. Neurosci. – volume: 248 start-page: 73 year: 1990 end-page: 76 ident: bib10 article-title: Two-photon laser scanning fluorescence microscopy publication-title: Science – volume: 91 start-page: 1908 year: 2004 end-page: 1912 ident: bib30 article-title: In vivo multiphoton microscopy of deep brain tissue publication-title: J. Neurophysiol. – volume: 208 start-page: 561 year: 2005 end-page: 569 ident: bib22 article-title: Rats are able to navigate in virtual environments publication-title: J. Exp. Biol. – volume: 4 start-page: 73 year: 2007 end-page: 79 ident: bib18 article-title: Imaging cellular network dynamics in three dimensions using fast 3D laser scanning publication-title: Nat. Methods – volume: 192 start-page: 777 year: 2006 end-page: 784 ident: bib43 article-title: How silent is the brain: is there a “dark matter” problem in neuroscience? publication-title: J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. – volume: 50 start-page: 617 year: 2006 end-page: 629 ident: bib16 article-title: Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice publication-title: Neuron – volume: 36 start-page: 350 year: 1992 end-page: 355 ident: bib2 article-title: The effect of isoflurane on excitatory synaptic transmission in the rat hippocampus publication-title: Acta Anaesthesiol. Scand. – volume: 87 start-page: 631 year: 2004 end-page: 639 ident: bib29 article-title: High sensitivity of Stark-shift voltage-sensing dyes by one- or two-photon excitation near the red spectral edge publication-title: Biophys. J. – volume: 14 start-page: 675 year: 2004 end-page: 684 ident: bib31 article-title: Persistent neural activity: prevalence and mechanisms publication-title: Curr. Opin. Neurobiol. – volume: 26 start-page: 12807 year: 2006 end-page: 12815 ident: bib13 article-title: Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades publication-title: J. Neurosci. – volume: 28 start-page: 41 year: 2000 end-page: 51 ident: bib15 article-title: Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP publication-title: Neuron – volume: 16 start-page: 543 year: 2006 end-page: 550 ident: bib41 article-title: New methods and uses for fast optical scanning publication-title: Curr. Opin. Neurobiol. – volume: 433 start-page: 597 year: 2005 end-page: 603 ident: bib36 article-title: Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex publication-title: Nature – volume: 410 start-page: 686 year: 2001 end-page: 690 ident: bib32 article-title: Hyperacute directional hearing in a microscale auditory system publication-title: Nature – volume: 27 start-page: 461 year: 2000 end-page: 468 ident: bib14 article-title: Active stabilization of electrodes for intracellular recording in awake behaving animals publication-title: Neuron – volume: 25 start-page: 1431 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib45 article-title: Octopamine and experience-dependent modulation of aggression in crickets publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.4258-04.2005 – volume: 454 start-page: 675 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib34 article-title: Calcium indicator loading of neurons using single-cell electroporation publication-title: Pflugers Arch. doi: 10.1007/s00424-007-0234-2 – volume: 103 start-page: 4753 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib48 article-title: Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2 publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0509378103 – volume: 5 start-page: e189 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib42 article-title: The functional microarchitecture of the mouse barrel cortex publication-title: PLoS Biol. doi: 10.1371/journal.pbio.0050189 – year: 2001 ident: 10.1016/j.neuron.2007.08.003_bib37 – volume: 30 start-page: 334 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib11 article-title: Are corticothalamic ‘up’ states fragments of wakefulness? publication-title: Trends Neurosci. doi: 10.1016/j.tins.2007.04.006 – volume: 16 start-page: 543 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib41 article-title: New methods and uses for fast optical scanning publication-title: Curr. Opin. Neurobiol. doi: 10.1016/j.conb.2006.08.011 – volume: 18 start-page: 351 year: 1997 ident: 10.1016/j.neuron.2007.08.003_bib8 article-title: Photon upmanship: why multiphoton imaging is more than a gimmick publication-title: Neuron doi: 10.1016/S0896-6273(00)81237-4 – volume: 27 start-page: 461 year: 2000 ident: 10.1016/j.neuron.2007.08.003_bib14 article-title: Active stabilization of electrodes for intracellular recording in awake behaving animals publication-title: Neuron doi: 10.1016/S0896-6273(00)00057-X – volume: 385 start-page: 161 year: 1997 ident: 10.1016/j.neuron.2007.08.003_bib47 article-title: In vivo dendritic calcium dynamics in neocortical pyramidal neurons publication-title: Nature doi: 10.1038/385161a0 – volume: 53 start-page: 789 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib33 article-title: In vivo simultaneous tracing and ca(2+) imaging of local neuronal circuits publication-title: Neuron doi: 10.1016/j.neuron.2007.02.018 – volume: 94 start-page: 3628 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib12 article-title: Optical recording of fast neuronal membrane potential transients in acute mammalian brain slices by second-harmonic generation microscopy publication-title: J. Neurophysiol. doi: 10.1152/jn.00416.2005 – volume: 31 start-page: 903 year: 2001 ident: 10.1016/j.neuron.2007.08.003_bib21 article-title: A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals publication-title: Neuron doi: 10.1016/S0896-6273(01)00421-4 – volume: 45 start-page: 279 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib24 article-title: Transient and persistent dendritic spines in the neocortex in vivo publication-title: Neuron doi: 10.1016/j.neuron.2005.01.003 – volume: 50 start-page: 617 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib16 article-title: Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice publication-title: Neuron doi: 10.1016/j.neuron.2006.03.043 – volume: 77 start-page: 257 year: 1989 ident: 10.1016/j.neuron.2007.08.003_bib39 article-title: A tutorial on hidden Markov-models and selected applications in speech recognition publication-title: Proc. IEEE doi: 10.1109/5.18626 – volume: 6 start-page: 219 year: 1982 ident: 10.1016/j.neuron.2007.08.003_bib4 article-title: Quantitative analysis of methods for reducing physiological brain pulsations publication-title: J. Neurosci. Methods doi: 10.1016/0165-0270(82)90085-1 – volume: 192 start-page: 777 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib43 article-title: How silent is the brain: is there a “dark matter” problem in neuroscience? publication-title: J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. doi: 10.1007/s00359-006-0117-6 – volume: 10 start-page: 549 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib52 article-title: Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex publication-title: Nat. Neurosci. doi: 10.1038/nn1883 – volume: 2 start-page: 989 year: 1999 ident: 10.1016/j.neuron.2007.08.003_bib20 article-title: In vivo dendritic calcium dynamics in deep-layer cortical pyramidal neurons publication-title: Nat. Neurosci. doi: 10.1038/14788 – volume: 446 start-page: 633 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib54 article-title: Multimodal fast optical interrogation of neural circuitry publication-title: Nature doi: 10.1038/nature05744 – volume: 441 start-page: 979 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib23 article-title: Experience-dependent and cell-type-specific spine growth in the neocortex publication-title: Nature doi: 10.1038/nature04783 – volume: 26 start-page: 12807 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib13 article-title: Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.3238-06.2006 – volume: 36 start-page: 350 year: 1992 ident: 10.1016/j.neuron.2007.08.003_bib2 article-title: The effect of isoflurane on excitatory synaptic transmission in the rat hippocampus publication-title: Acta Anaesthesiol. Scand. doi: 10.1111/j.1399-6576.1992.tb03480.x – volume: 100 start-page: 7319 year: 2003 ident: 10.1016/j.neuron.2007.08.003_bib46 article-title: In vivo two-photon calcium imaging of neuronal networks publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1232232100 – volume: 7 start-page: 446 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib5 article-title: Large-scale recording of neuronal ensembles publication-title: Nat. Neurosci. doi: 10.1038/nn1233 – ident: 10.1016/j.neuron.2007.08.003_bib27 – volume: 28 start-page: 41 year: 2000 ident: 10.1016/j.neuron.2007.08.003_bib15 article-title: Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP publication-title: Neuron doi: 10.1016/S0896-6273(00)00084-2 – volume: 8 start-page: 1263 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib3 article-title: Millisecond-timescale, genetically targeted optical control of neural activity publication-title: Nat. Neurosci. doi: 10.1038/nn1525 – volume: 97 start-page: 3118 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib51 article-title: Two-photon calcium imaging of network activity in XFP-expressing neurons in the mouse publication-title: J. Neurophysiol. doi: 10.1152/jn.01207.2006 – volume: 3 start-page: e355 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib28 article-title: From art to engineering? The rise of in vivo mammalian electrophysiology via genetically targeted labeling and nonlinear imaging publication-title: PLoS Biol. doi: 10.1371/journal.pbio.0030355 – volume: 91 start-page: 1908 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib30 article-title: In vivo multiphoton microscopy of deep brain tissue publication-title: J. Neurophysiol. doi: 10.1152/jn.01007.2003 – volume: 2 start-page: 13 year: 2003 ident: 10.1016/j.neuron.2007.08.003_bib38 article-title: ScanImage: flexible software for operating laser scanning microscopes publication-title: Biomed. Eng. Online doi: 10.1186/1475-925X-2-13 – volume: 30 start-page: 2272 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib17 article-title: In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope publication-title: Opt. Lett. doi: 10.1364/OL.30.002272 – volume: 22 start-page: 76 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib49 article-title: Influence of genetic background on daily running-wheel activity differs with aging publication-title: Physiol. Genomics doi: 10.1152/physiolgenomics.00243.2004 – volume: 102 start-page: 14063 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib26 article-title: Imaging input and output of neocortical networks in vivo publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0506029102 – volume: 87 start-page: 631 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib29 article-title: High sensitivity of Stark-shift voltage-sensing dyes by one- or two-photon excitation near the red spectral edge publication-title: Biophys. J. doi: 10.1529/biophysj.104.040477 – volume: 9 start-page: 283 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib53 article-title: Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging publication-title: Nat. Neurosci. doi: 10.1038/nn1635 – volume: 433 start-page: 597 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib36 article-title: Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex publication-title: Nature doi: 10.1038/nature03274 – volume: 248 start-page: 73 year: 1990 ident: 10.1016/j.neuron.2007.08.003_bib10 article-title: Two-photon laser scanning fluorescence microscopy publication-title: Science doi: 10.1126/science.2321027 – volume: 1 start-page: 31 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib35 article-title: Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo publication-title: Nat. Methods doi: 10.1038/nmeth706 – volume: 410 start-page: 686 year: 2001 ident: 10.1016/j.neuron.2007.08.003_bib32 article-title: Hyperacute directional hearing in a microscale auditory system publication-title: Nature doi: 10.1038/35070564 – volume: 273 start-page: 1868 year: 1996 ident: 10.1016/j.neuron.2007.08.003_bib1 article-title: Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses publication-title: Science doi: 10.1126/science.273.5283.1868 – volume: 439 start-page: 201 year: 1999 ident: 10.1016/j.neuron.2007.08.003_bib40 article-title: Two-photon Na+ imaging in spines and fine dendrites of central neurons publication-title: Pflugers Arch. – volume: 4 start-page: 73 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib18 article-title: Imaging cellular network dynamics in three dimensions using fast 3D laser scanning publication-title: Nat. Methods doi: 10.1038/nmeth989 – volume: 9 start-page: 816 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib50 article-title: Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo publication-title: Nat. Neurosci. doi: 10.1038/nn1703 – volume: 208 start-page: 561 year: 2005 ident: 10.1016/j.neuron.2007.08.003_bib22 article-title: Rats are able to navigate in virtual environments publication-title: J. Exp. Biol. doi: 10.1242/jeb.01371 – volume: 92 start-page: 3121 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib25 article-title: In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy publication-title: J. Neurophysiol. doi: 10.1152/jn.00234.2004 – volume: 4 start-page: 127 year: 2007 ident: 10.1016/j.neuron.2007.08.003_bib19 article-title: Improved calcium imaging in transgenic mice expressing a troponin C-based biosensor publication-title: Nat. Methods doi: 10.1038/nmeth1009 – volume: 2 start-page: e329 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib9 article-title: Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructure publication-title: PLoS Biol. doi: 10.1371/journal.pbio.0020329 – volume: 9 start-page: 608 year: 2006 ident: 10.1016/j.neuron.2007.08.003_bib6 article-title: Correlating whisker behavior with membrane potential in barrel cortex of awake mice publication-title: Nat. Neurosci. doi: 10.1038/nn1690 – volume: 14 start-page: 675 year: 2004 ident: 10.1016/j.neuron.2007.08.003_bib31 article-title: Persistent neural activity: prevalence and mechanisms publication-title: Curr. Opin. Neurobiol. doi: 10.1016/j.conb.2004.10.017 – volume: 19 start-page: 735 year: 1997 ident: 10.1016/j.neuron.2007.08.003_bib44 article-title: A genetically encoded optical probe of membrane voltage publication-title: Neuron doi: 10.1016/S0896-6273(00)80955-1 – volume: 36 start-page: 685 year: 1980 ident: 10.1016/j.neuron.2007.08.003_bib7 article-title: A simple apparatus to investigate the orientation of walking insects publication-title: Experientia doi: 10.1007/BF01970140
SSID	ssj0014591
Score	2.497551
Snippet	We report a technique for two-photon fluorescence imaging with cellular resolution in awake, behaving mice with minimal motion artifact. The apparatus combines... We report a technique for two-photon fluorescence imaging with cellular resolution in awake behaving mice with minimal motion artifact. The apparatus combines...
SourceID	unpaywall pubmedcentral proquest pubmed crossref elsevier
SourceType	Open Access Repository Aggregation Database Index Database Enrichment Source Publisher
StartPage	43
SubjectTerms	Algorithms Animals Astrocytes - physiology Behavior, Animal Brain - cytology Diagnostic Imaging - instrumentation Diagnostic Imaging - methods Equipment Design Exercise Test - methods Female Fitness equipment Luminescent Proteins - metabolism Male Markov Chains Mice Mice, Transgenic Models, Neurological Motor Activity - physiology Neurons Neurons - physiology Organic Chemicals - metabolism SYSNEURO Wakefulness - physiology Walking
SummonAdditionalLinks	– databaseName: ScienceDirect Free and Delayed Access Journal dbid: IXB link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9swED8hpGl7QQy2UT42P0x7WtYkjuPksVRDgMYexpD6FjmuoxVSt4JWqP89d3aSrUIbE29Vc7Za-3wfzu_uB_Axj8cmlloFlZEaE5RxGiiOnzD2z9Ghj0upHNrie3p6lZyPxGgDhm0tDMEqG9vvbbqz1s03_WY1-_PJpH8ZZjl1LyelpbSGivh4khF9w9nouHuTkAjPmofCAUm35XMO4-V6RtqmkSGBKvnf3NPj8PMxivLl0s7V6l7V9R8u6mQbtprYkg38z38NG8buwO7AYl49XbFPzKE93TX6DrzwJJSrXfhxNnVMRewbgcKDS9w0w6hnB02lPbkEo-taNjR1TahVRnf-XmPZxLLBvboxn9nFrEQLwy7Q8ryBq5OvP4enQcO0EGgRh4sgzaK0EkYlUaY0pSDCSKNNpNGb6zhRYZXlMQV7RpQ6E-OcykpCrlWU6CrJS_4WNu3Mmj1gJuVhWVUqS1VJuWlZRVxjoGEiHBUa0QPeLnChmzbkxIZRFy3e7Lrw20IMmbIgksyQ9yDoRs19G44n5GW7d8WaOhXoKZ4YedhuddEc57sCo2YCD6Er78GH7jEeRHq7oqyZLe9wDome_l8SKRXMiEj24J3XnN9_ReaEbcOxck2nOgFqAr7-xE5-uWbgGD5nYYxzfum0779WaP_ZK3QAr9wFN6EokkPYXNwuzRFGZovyvTt6D1SVN1s priority: 102 providerName: Elsevier
Title	Imaging Large-Scale Neural Activity with Cellular Resolution in Awake, Mobile Mice
URI	https://dx.doi.org/10.1016/j.neuron.2007.08.003 https://www.ncbi.nlm.nih.gov/pubmed/17920014 https://www.proquest.com/docview/1503760284 https://www.proquest.com/docview/20784784 https://www.proquest.com/docview/68360517 https://pubmed.ncbi.nlm.nih.gov/PMC2268027 http://www.cell.com/article/S0896627307006149/pdf
UnpaywallVersion	publishedVersion
Volume	56
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 1097-4199 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0014591 issn: 0896-6273 databaseCode: KQ8 dateStart: 19950201 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVESC databaseName: Elsevier Free Content customDbUrl: eissn: 1097-4199 dateEnd: 20241102 omitProxy: true ssIdentifier: ssj0014591 issn: 0896-6273 databaseCode: IXB dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 1097-4199 dateEnd: 20241102 omitProxy: true ssIdentifier: ssj0014591 issn: 0896-6273 databaseCode: DIK dateStart: 19950101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVLSH databaseName: Elsevier Journals customDbUrl: mediaType: online eissn: 1097-4199 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0014591 issn: 0896-6273 databaseCode: AKRWK dateStart: 19880301 isFulltext: true providerName: Library Specific Holdings
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3db9MwED9trRC88LHxURjFD4gn0uXLcfwYJqaNsQl1VJSnyHYcMdalFWs1lb-eOycpTBVsvEXKnZXEF_t39s-_A3gtw8KGwiivtMJgglIknorwCrG_xAm90EI5tsVJcjCKP4z5eAPawoXEqqQVazdGN99u99RPJemUU3hSAiN3Z0W5Cd2EI_zuQHd08in76tCiTDyyczucUtAOp2yPyzlOl9OIrBrhQiJRRn-bjtbh5jpr8u6imqnllZpM_piS9h_AsD3YUzNRzgeLuR6Yn-s6j7d_24dwvwGoLKvtHsGGrbZgO6swOb9YsjfMUUbdWvwW3KkrWS63YXh44codsY_ELPdOsectI-EPasrUFSoYrfmyPXwSor4y2jiow56dVSy7Uuf2LTueahym2DEOX49htP_-896B15Rr8AwP_bmXpEFScqviIFWG8hhuhTU2MAgJTBgrv0xlSIjRcm1SXkg6m-JHRgWxKWOpoyfQqaaVfQbMJpGvy1KlidKU4OoyiAyiFRugl295D6K213LTaJlTSY1J3pLWvud1X1OZTZFTpU0_6oG38prVWh432Is2IPIGj9Q4I8fp5gbPnTZ-8mZMuMwRehMDCfFAD16tbuPfTCGgKjtdXGIbAuHCvywSOnXDA9GDp3U4_n4VIYkgh77iWqCuDEhJ_Pqd6uybUxRHDJ76IbY5WIX0rb7Q8_91eAH33OI4MTDiHejMfyzsS0R1c92HbnY0_HLUh83D8bt-81f_AowgS9I
linkProvider	Unpaywall
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-NITReEGx8FAbzA-KJ0Hw5Th5LxdRBuwe2SX2zHNfRCplbsVZT_3vu7CRQTTDEW9WcrdY-3_3O-d0dwNsinplYaBVURmgMUGZZoBL8hNi_QIc-K4VybIvTbHSRfp7y6Q4M21wYolU2tt_bdGetm2_6zWr2l_N5_yzMC6peTkpLYU1xD-6nHNEJZfFNP3avElLu2-ahdEDibf6cI3m5opG2qWRIrMrkT_7pNv68TaPcW9ul2tyouv7NRx0_hkcNuGQD__ufwI6x-3AwsBhYX23YO-bonu4efR8e-C6UmwP4enLlWhWxMbHCgzPcNcOoaAdNpX13CUb3tWxo6ppoq4wu_b3Ksrllgxv13bxnk0WJJoZN0PQ8hYvjT-fDUdC0Wgg0j8NVkOVRVnGj0ihXmmIQboTRJtLoznWcqrDKi5jQnuGlzvmsoLySMNEqSnWVFmXyDHbtwpoXwEyWhGVVqTxTJQWnZRUlGpGGiXBUaHgPknaBpW7qkFM7jFq2hLNv0m8LtcgUkrpkhkkPgm7U0tfhuENetHsnt_RJoqu4Y-Rhu9WyOc_XEmEzsYfQl_fgqHuMJ5FeryhrFutrnEOgq_-bREYZMzwSPXjuNefXXxEFkdtwrNjSqU6AqoBvP7HzS1cNHPFzHsY454dO-_5phV7-9wodwd7ofDKW45PTL6_gobvtJkpFegi7qx9r8xph2qp8447hTwcxOoE
linkToUnpaywall	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3fb9MwED6NTghe-LEBKwzwA-KJdPllO36sJqaB2IQ2Ko2nyHEcbaxzq63VVP567uykMFWw8RYpd1YSX-zv7M_fAbxTaW1TaXTUWGkwQalFpDO8QuyvcEKvK6k92-JQ7I_yzyf8ZA26woXEqqQVaz9Gt99u5zguFOmUU3hSAqN2pnVzD9YFR_jdg_XR4dfhd48WlYjIzu9wKkk7nKo7Luc5XV4j0rXChUSizP42Ha3CzVXW5IO5m-rFtR6P_5iS9h7DUXewJzBRzgfzWTUwP1d1Hu_-tk_gUQtQ2TDYPYU16zZgc-gwOb9YsPfMU0b9WvwG3A-VLBebcPTpwpc7Yl-IWR4dY89bRsIf1JQJFSoYrfmyXXwSor4y2jgIYc_OHBte63P7gR1MKhym2AEOX89gtPfx2-5-1JZriAxP41kkikQ03Oo8KbShPIZbaY1NDEICk-Y6bgqVEmK0vDIFrxWdTYkzo5PcNLmqsufQcxNnt4BZkcVV0-hC6IoS3KpJMoNoxSboFVveh6zrtdK0WuZUUmNcdqS1H2XoayqzKUuqtBlnfYiWXtOg5XGLvewComzxSMAZJU43t3hud_FTtmPCVYnQmxhIiAf68HZ5G_9mCgHt7GR-hW1IhAv_shB06oYnsg8vQjj-fhWpiCCHvvJGoC4NSEn85h13duoVxRGDF3GKbQ6WIX2nL_Tyfx1ewUO_OE4MjHwberPLuX2NqG5WvWn_4198JUkr
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Imaging+Large-Scale+Neural+Activity+with+Cellular+Resolution+in+Awake%2C+Mobile+Mice&rft.jtitle=Neuron+%28Cambridge%2C+Mass.%29&rft.au=Dombeck%2C+Daniel+A&rft.au=Khabbaz%2C+Anton+N&rft.au=Collman%2C+rest&rft.au=Adelman%2C+Thomas+L&rft.date=2007-10-04&rft.issn=0896-6273&rft.volume=56&rft.issue=1&rft.spage=43&rft.epage=57&rft_id=info:doi/10.1016%2Fj.neuron.2007.08.003&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0896-6273&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0896-6273&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0896-6273&client=summon