Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens - Arbuckle, Jesse H.; Gardina, Paul J.; Gordon, David N.; Hickman, Heather D.; Yewdell, Jonathan W.; Pierson, Theodore C.; Myers, Timothy G.; Kristie, Thomas M. (mBio, 2017)
Keywords: antiviral; Antiviral Agents - pharmacology; chromatin; DNA Replication; Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors; Enzyme Inhibitors - pharmacology; Epigenetic Repression; epigenetics; Herpes Simplex - drug therapy; Herpes Simplex - immunology; Herpes Simplex - virology; herpesvirus; Herpesvirus 1, Human - drug effects; Herpesvirus 1, Human - genetics; Herpesvirus 1, Human - pathogenicity; Herpesvirus 1, Human - physiology; Humans; immune mechanisms; Immunity, Innate; innate immunity; Polycomb Repressive Complex 2 - antagonists & inhibitors; Virus Latency; Virus Replication - drug effects; Zika Virus - drug effects; Zika Virus - genetics; Zika Virus - pathogenicity; Zika Virus - physiology; Zika Virus Infection - immunology; Zika Virus Infection - virology; innate immunity; herpesvirus; immune mechanisms; antiviral; Zika virus; chromatin; epigenetics