Pharmacokinetics, immunogenicity and bioactivity of the therapeutic antibody catumaxomab intraperitoneally administered to cancer patients - Ruf, Peter; Kluge, Michael; Jäger, Michael; Burges, Alexander; Volovat, Constantin; Heiss, Markus Maria; Hess, Jürgen; Wimberger, Pauline; Brandt, Birgit; Lindhofer, Horst (British journal of clinical pharmacology, 2010)
Keywords: Antibodies, Bispecific - blood; Antibodies, Bispecific - immunology; Antibodies, Bispecific - pharmacokinetics; Antibodies, Monoclonal - blood; Ascites - metabolism; Biological and medical sciences; Biological Availability; catumaxomab; Cytokines - analysis; Enzyme-Linked Immunosorbent Assay - methods; Humans; immunogenicity; Immunologic Factors - blood; Immunologic Factors - immunology; Immunologic Factors - pharmacokinetics; Injections, Intraperitoneal; intraperitoneal infusion; malignant ascites; Medical sciences; Neoplasms - drug therapy; Pharmacodynamics; pharmacokinetics; Pharmacology. Drug treatments; Antineoplastic agent; Human; Immune response; Monoclonal antibody; Malignant tumor; Biological activity; Intraperitoneal; Infusion; Catumaxomab; Treatment; malignant ascites; Immunogenicity; intraperitoneal infusion; Perfusion; Malignant effusion; Pharmacokinetics; Cancer; pharmacokinetics; catumaxomab; immunogenicity