Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation - Zhu, Haiyan; Guo, Qing; Mattson, Mark P (Brain research, 1999)
Keywords: Alzheimer; Alzheimer Disease - genetics; Animals; Apoptosis; Biological and medical sciences; Body Weight - physiology; Calorie restriction; Cell Death - physiology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Diet; Eating - physiology; Excitatory Amino Acid Agonists - toxicity; Excitotoxicity; Hippocampus - cytology; Hippocampus - physiology; Hyroxynonenal; Kainate; Kainic Acid - toxicity; Lipid Peroxidation - drug effects; Medical sciences; Membrane Proteins - genetics; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neurology; Oxidative stress; Presenilin-1; Oxidative stress; Kainate; Hyroxynonenal; Excitotoxicity; Calorie restriction; Alzheimer; Apoptosis; Nervous system diseases; Rat; Alzheimer disease; Rodentia; Central nervous system; Presenilin; Cerebral disorder; Vertebrata; Mammalia; Mouse; Animal; Central nervous system disease; Degenerative disease; Mutation; Hippocampus; Brain (vertebrata)