Safety of AAV Factor IX Peripheral Transvenular Gene Delivery to Muscle in Hemophilia B Dogs - Haurigot, Virginia; Mingozzi, Federico; Buchlis, George; Hui, Daniel J; Chen, Yifeng; Basner-Tschakarjan, Etiena; Arruda, Valder R; Radu, Antoneta; Franck, Helen G; Wright, J Fraser; Zhou, Shangzhen; Stedman, Hansell H; et al. (Molecular therapy, 2010)
Keywords: Animals; Antibodies; Antigens; CD4-Positive T-Lymphocytes - metabolism; Cell Line; Cytokines; Dependovirus - genetics; Disease; Dogs; Drug dosages; Enzymes; Factor IX - genetics; Factor IX - metabolism; Flow Cytometry; Genetic Vectors - adverse effects; Genetic Vectors - genetics; Hemophilia; Hemophilia B - metabolism; Hemophilia B - therapy; Hospitals; Humans; Immunoglobulin G - metabolism; Interferon-gamma - metabolism; Interleukin-10 - metabolism; Muscle, Skeletal - metabolism; Muscle, Skeletal - pathology; Original; Peptides; United States--US; Pennsylvania