Relation of early tumor shrinkage (ETS) observed in first‐line treatment to efficacy parameters of subsequent treatment in FIRE‐3 (AIOKRK0306) - Modest, Dominik P.; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling‐Kaiser, Ursula; Al‐Batran, Salah‐Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; et al. (International journal of cancer, 2017)
Keywords: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols - administration & dosage; bevacizumab; Bevacizumab - administration & dosage; Camptothecin - administration & dosage; Camptothecin - analogs & derivatives; Cancer; cetuximab; Cetuximab - administration & dosage; Clinical trials; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - drug therapy; Colorectal Neoplasms - genetics; Colorectal Neoplasms - pathology; Disease-Free Survival; early tumor shrinkage; Female; Fluorouracil - administration & dosage; Humans; Immunotherapy; Kaplan-Meier Estimate; KRAS; Leucovorin - administration & dosage; Male; Medical research; Metastases; Metastasis; Middle Aged; Monoclonal antibodies; Proto-Oncogene Proteins p21(ras) - genetics; RAS; Remission Induction; sequence; Shrinkage; Survival; Targeted cancer therapy; Treatment Outcome; sequence; colorectal cancer; RAS; bevacizumab; cetuximab; KRAS; early tumor shrinkage