Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification - Deans, Richard M; Morgens, David W; Ökesli, Ayşe; Pillay, Sirika; Horlbeck, Max A; Kampmann, Martin; Gilbert, Luke A; Li, Amy; Mateo, Roberto; Smith, Mark; Glenn, Jeffrey S; Carette, Jan E; et al. (Nature chemical biology, 2016)
Keywords: 49/40; 631/154; 631/326/596; 631/92/507; 631/92/555; Antiviral Agents - pharmacology; Biochemical Engineering; Biochemistry; Bioorganic Chemistry; Biosynthesis; Carbazoles - chemistry; Carbazoles - pharmacology; Cell Biology; Cell Line, Tumor; Chemistry; Chemistry/Food Science; Cloning, Molecular; CRISPR-Cas Systems - genetics; Cytotoxicity; Dehydrogenase; Dengue virus; Drug resistance; Drugs; Humans; Lentivirus - drug effects; Lentivirus - physiology; Ribonucleic acid; RNA; RNA, Small Interfering - genetics; Vector-borne diseases; Viruses