Anaphylaxis induced by indocyanine green during abdominal surgery: A case report

Since 2011, indocyanine green (ICG) has been increasingly used in surgery as a diagnostic tool. Although allergic reactions to this fluorescent dye are considered rare, they can result in anaphylactic shock. We report the case of a 33-year-old woman who developed anaphylaxis immediately after ICG ad...

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Published inSaudi journal of anaesthesia Vol. 18; no. 4; pp. 590 - 592
Main Authors Sasaki, Momoko, Murata, Yuya
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer - Medknow 01.10.2024
Wolters Kluwer Medknow Publications
Edition2
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ISSN1658-354X
0975-3125
DOI10.4103/sja.sja_260_24

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Summary:Since 2011, indocyanine green (ICG) has been increasingly used in surgery as a diagnostic tool. Although allergic reactions to this fluorescent dye are considered rare, they can result in anaphylactic shock. We report the case of a 33-year-old woman who developed anaphylaxis immediately after ICG administration during laparoscopic-assisted high anterior resection. The patient was treated with intravenous adrenaline, and the surgery continued. Elevated plasma histamine and serum tryptase levels immediately after ICG administration and intradermal testing identified ICG as the causative agent. The frequency of ICG use is increasing, and anesthesiologists should recognize ICG as a prevalent perioperative allergen.
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ISSN:1658-354X
0975-3125
DOI:10.4103/sja.sja_260_24