Cytochrome P450 2D6 genotype–phenotype characterization through population pharmacokinetic modeling of tedatioxetine - Frederiksen, Trine; Areberg, Johan; Schmidt, Ellen; Stage, Tore Bjerregaard; Brøsen, Kim (CPT: pharmacometrics and systems pharmacology, 2021)
Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Antidepressive Agents - pharmacokinetics; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytochrome; Cytochrome P-450 CYP2D6 - genetics; Datasets; Drug dosages; Drug interactions; Enzymes; Ethnicity; Female; Genotype; Genotype & phenotype; Humans; Laboratories; Male; Metabolism; Metabolites; Middle Aged; Models, Biological; Oral administration; Pharmacokinetics; Phenotype; Plasma; Population; Young Adult