The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors - Šebera, Jakub; Dubankova, Anna; Sychrovský, Vladimír; Ruzek, Daniel; Boura, Evzen; Nencka, Radim (Scientific reports, 2018)
Keywords: 119/118; 631/114/2397; 631/326/596; Adenosine - analogs & derivatives; Adenosine - chemistry; Adenosine - pharmacology; Antiviral agents; DNA-directed RNA polymerase; Fetuses; Global health; Health risks; Humanities and Social Sciences; Humans; Magnesium; Magnesium - chemistry; Models, Molecular; Molecular Docking Simulation; multidisciplinary; Nucleoside analogs; Nucleosides - chemistry; Nucleotide analogs; Nucleotides - chemistry; Polyphosphates - chemistry; Protein Conformation - drug effects; RNA - chemistry; RNA - genetics; RNA polymerase; RNA Replicase - chemistry; RNA Replicase - genetics; RNA viruses; RNA-directed RNA polymerase; Science; Science (multidisciplinary); Vaccination; Vector-borne diseases; Viral Nonstructural Proteins - chemistry; Viral Nonstructural Proteins - genetics; Virus Replication - genetics; Zika virus; Zika Virus - chemistry; Zika Virus - genetics; Zika Virus - pathogenicity; Zika Virus Infection - genetics; Zika Virus Infection - virology