SQ1274, a novel microtubule inhibitor, inhibits ovarian and uterine cancer cell growth - Mills, Kathryn A.; Roach, S. Tanner; Quinn, Jeanne M.; Guo, Lei; Beck, Hollie M.; Lomonosova, Elena; Ilivicky, Anna R.; Starks, Courtney M.; Lawrence, Julie A.; Hagemann, Andrea R.; McCourt, Carolyn; Thaker, Premal H.; et al. (Gynecologic oncology, 2018)
Keywords: Animals; Apoptosis - drug effects; Carcinoma, Ovarian Epithelial; Cell Cycle - drug effects; Cell Growth Processes - drug effects; Cell Line, Tumor; Cystadenocarcinoma, Serous - drug therapy; Cystadenocarcinoma, Serous - genetics; Cystadenocarcinoma, Serous - metabolism; Cystadenocarcinoma, Serous - pathology; Endometrial Neoplasms - drug therapy; Endometrial Neoplasms - genetics; Endometrial Neoplasms - metabolism; Endometrial Neoplasms - pathology; Female; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Glandular and Epithelial - drug therapy; Neoplasms, Glandular and Epithelial - genetics; Neoplasms, Glandular and Epithelial - metabolism; Neoplasms, Glandular and Epithelial - pathology; Ovarian Neoplasms - drug therapy; Ovarian Neoplasms - genetics; Ovarian Neoplasms - metabolism; Ovarian Neoplasms - pathology; Paclitaxel - pharmacology; Proto-Oncogene Proteins - biosynthesis; Proto-Oncogene Proteins - genetics; Receptor Protein-Tyrosine Kinases - biosynthesis; Receptor Protein-Tyrosine Kinases - genetics; RNA, Neoplasm - biosynthesis; RNA, Neoplasm - genetics; Tubulin Modulators - pharmacology; Xenograft Model Antitumor Assays